Results 181 to 190 of about 265,748 (319)

Maternal RSV vaccination for infant protection: A systematic review and meta‐analysis of phase 3 trials with an integrated economic evaluation

International Journal of Gynecology &Obstetrics, Volume 173, Issue 1, Page 63-73, April 2026.
Abstract Background Respiratory syncytial virus (RSV) is a leading cause of hospitalization and mortality in early infancy. Maternal immunization offers a preventive strategy, but uncertainties regarding safety and economic value have limited its implementation.
Johnatan Torres‐Torres, Lourdes Rojas‐Zepeda, José Rafael Villafan‐Bernal, Raigam Martinez‐Portilla, Salvador Espino‐y‐Sosa, Pablo Cerda‐Flores, Elsa Romelia Moreno‐Verduzco, Irma Eloisa Monroy‐Muñoz, Ameyran Yolanda Gonzalez‐Guerrero, Juan Mario Solis‐Paredes, Javier Perez Duran   +10 more
wiley   +1 more source

Mass‐Standardised Differential Antibody Binding to a Spectrum of SARS‐CoV‐2 Variant Spike Proteins: Wuhan, Alpha, Beta, Gamma, Delta, Omicron BA.1, BA.4/5, BA.2.75 and BA.2.12.1 Variants—Antibody Immunity Endotypes

Immunology, Volume 177, Issue 4, Page 798-809, April 2026.
Fully quantitative, mass‐standardised, antibody responses to ten SARS‐CoV‐2 variants show significant variation in immunity profiles or endotypes. The incidence of the complete response to all variants is significantly improved after three vaccinations.
Philip H. James‐Pemberton, Shivali Kohli, Jordan Twynham, Aaron C. Westlake, Alex Antill, Rouslan V. Olkhov, Andrew M. Shaw   +6 more
wiley   +1 more source

Multivalent Protein Nanorings for Broad and Potent SARS‐CoV‐2 Neutralization

Advanced Healthcare Materials, Volume 15, Issue 10, 13 March 2026.
A protein‐only, modular multivalent nanoscaffold displaying 20 anchor points, decorated with two different binders (10 of each), targeting the SARS‐CoV‐2 receptor‐binding domain is presented. The construct self‐assembles into stable, biocompatible, homogeneous nanoparticles, exhibit synergistic binding with fM IC50 values. It also detects spike at 9 ng 
Molood Behbahanipour, Carla Goldin, Cecilia Arahi Prato, Ana Luz Paletta, Oriol Bárcenas, Susanna Navarro, Jordi Pujols, Daniel H. Murgida, María Virginia Tribulatti, Sebastián Esperante, Damian Alvarez‐Paggi, Salvador Ventura   +11 more
wiley   +1 more source

High‐Throughput In Vivo Screening Using Barcoded mRNA Identifies Lipid Nanoparticles With Extrahepatic Tropism for In Situ Immunoengineering

Advanced Materials, Volume 38, Issue 13, 3 March 2026.
A high‐throughput in vivo mRNA LNP screening platform is developed and employed to screen a large library of 122 mRNA LNPs in vivo for delivery to immune, stromal, and parenchymal cells, identifying promising LNP candidates. A novel small particle flow cytometry‐based protein adsorption analysis method is utilized to interrogate protein corona ...
Alex G. Hamilton, Ajay S. Thatte, Junchao Xu, Zhangyi Luo, Hannah C. Safford, Kelsey L. Swingle, Jenna Muscat‐Rivera, Michael Kegel, Xuexiang Han, Ryann A. Joseph, Amanda M. Murray, Hannah C. Geisler, Ricardo C. Whitaker, Lulu Xue, Roman Spektor, Jilian R. Melamed, Drew Weissman, Michael J. Mitchell   +17 more
wiley   +1 more source

Prevalence of Respiratory Syncytial Virus Among Children Under 5 Years of Age in Sub-Saharan Africa

Global Pediatric Health
Background . Pneumonia and bronchiolitis are common childhood illnesses caused by the respiratory syncytial virus. A systematic analysis of published epidemiological data in sub-Saharan African children under the age of 5 was conducted. Methods .
Habtamu Mitiku MSc, Tewodros Tesfa MSc, Mekuria Edae MSc, Nega Assefa PhD   +3 more
doaj   +1 more source

Sensitivity and Precision of Search Strategies Built Using a Text‐Mining Word Frequency Tool (PubReMiner) Compared to Current Best Practice for Building Search Strategies: A Study Within a Review (SWAR)

Cochrane Evidence Synthesis and Methods, Volume 4, Issue 2, March 2026.
ABSTRACT Objective PubReMiner is a text‐mining tool that analyses a seed set of citations to assess word frequency in titles, abstracts, and Medical Subject Headings (MeSH). This study aimed to determine the sensitivity and precision of search strategies developed using the PubReMiner tool compared to conventional search strategies developed by a ...
Andrew Dullea, Marie Carrigan, Lydia O'Sullivan, Isabelle Delaunois, Helen Clark, Martin Boudou, Martina Giusti, Kieran A. Walsh, Patricia Harrington, Susan M. Smith, Máirín Ryan   +10 more
wiley   +1 more source

Influenza virus infection drives upregulation of CD84 across a broad range of immune cells

Clinical &Translational Immunology, Volume 15, Issue 3, March 2026.
Our findings reveal a link between high CD84 expression in humans and recovery from respiratory viral infections. In influenza virus‐infected mice, CD84 is upregulated on a broad range of innate and adaptive immune cell populations, particularly on activated and influenza virus‐specific T‐cell populations and associated with less disease severity ...
Xiaoxiao Jia, Isabelle JH Foo, Hayley A McQuilten, Jeremy Chase Crawford, Aira F Cabug, Deborah Gebregzabher, Janet Chou, Robert C Mettelman, Tanya Novak, Lee‐Ann Van de Velde, Ryan S Thwaites, Adrienne G Randolph, Paul G Thomas, Jianqing Xu, Zhongfang Wang, Katherine Kedzierska, Lukasz Kedzierski, Brendon Y Chua   +17 more
wiley   +1 more source

Viral Immunity in Immunoglobulin Products: Global Immunity Debt and Autoimmunity in the Postpandemic Era

European Journal of Immunology, Volume 56, Issue 3, March 2026.
Immunoglobulin products derived from pooled global plasma reflect population‐level antiviral immunity. Analysis of batches from 2017 to 2023 reveals pandemic‐driven shifts in viral antibody profiles and a concurrent rise in autoantibodies, notably against TRIM21/Ro52, highlighting links between SARS‐CoV‐2, immunity debt, and autoimmunity.
Hannes Lindahl, Katy Shaw‐Saliba, H. Benjamin Larman, C. I. Edvard Smith, Peter Bergman   +4 more
wiley   +1 more source

Heterogeneous Activated B Cell Compartments Arising Early and Transiently After SARS‐CoV‐2 Vaccination

European Journal of Immunology, Volume 56, Issue 3, March 2026.
Characterization of the early antigen‐specific B cell response post‐SARS‐CoV‐2 vaccination reveals novel activated B cell clusters, showing different phenotypes and contraction dynamics. Some short‐lived activated B cells expressed both CD71 and the extrafollicular marker CD11c.
Laura Fernandez Blanco, Lisan H. Kuijper, Laura Y.L. Kummer, Niels J.M. Verstegen, Amélie Bos, Mathieu Claireaux, Mariël C. Duurland, Tineke Jorritsma, Maurice Steenhuis, Gius Kerster, Juan J. Garcia Vallejo, Marit J. van Gils, Koos P.J. van Dam, Eileen W. Stalman, Luuk Wieske, Laura Boekel, Gertjan J. Wolbink, Sander W. Tas, Theo Rispens, Taco W. Kuijpers, Filip Eftimov, Anja ten Brinke, S. Marieke van Ham, of T2B! Immunity Against SARS‐CoV‐2 Study Group   +23 more
wiley   +1 more source

The Burden of Acute Respiratory Infections on Emergency Departments: A Retrospective Study From a University Hospital in Central Italy

Health Science Reports, Volume 9, Issue 3, March 2026.
ABSTRACT Background and Aims Acute respiratory infections (ARIs) have a relevant impact on public health in terms of prevalence and costs associated with the diseases. While the COVID‐19 pandemic highlighted the need to adopt accurate surveillance systems to face new emergencies, the aim of our work is to describe ARIs other then COVID‐19 and their ...
Nunzio Zotti, Francesca Di Serafino, Luca Carmisciano, Laura Baglietto, Michele Cristofano, Francesca Foltran, Ombretta Paolilli, Andrea Davide Porretta, Guglielmo Arzilli, Mauro Pistello, Caterina Rizzo   +10 more
wiley   +1 more source