Results 21 to 30 of about 126,896 (285)

CAF08 adjuvant enables single dose protection against respiratory syncytial virus infection in murine newborns

Nature Communications, 2022
Respiratory syncytial virus is a major pathogen with burden observed and associated with childhood infection. Here the authors characterise a cationic adjuvant formulation and show single immunisation results in protection in a murine neonate model of ...
Simon D. van Haren, Gabriel K. Pedersen, Azad Kumar, Tracy J. Ruckwardt, Syed Moin, Ian N. Moore, Mahnaz Minai, Mark Liu, Jensen Pak, Francesco Borriello, Simon Doss-Gollin, Elisabeth M. S. Beijnen, Saima Ahmed, Michaela Helmel, Peter Andersen, Barney S. Graham, Hanno Steen, Dennis Christensen, Ofer Levy   +18 more
doaj   +1 more source

Genetic relatedness of infecting and reinfecting respiratory syncytial virus strains identified in a birth cohort from rural Kenya [PDF]

, 2012
Background: Respiratory syncytial virus (RSV) reinfects individuals repeatedly. The extent to which this is a consequence of RSV antigenic diversity is unclear.
Alexander G. Mwihuri, Anderson, Cane, Cane, Cane, Cane, Cane, Charles J. Sande, Charles N. Agoti, Choi, Clayton O. Onyango, Collins, D. James Nokes, Falsey, Falsey, Glezen, Graham F. Medley, Gunson, Hall, Hall, Hall, Henderson, Johnson, Johnson, Melero, Mufson, Mufson, Nair, Nokes, Nokes, Ohuma, Okiro, Parveen, Patricia A. Cane, Peret, Peret, Posada, Sande, Scott, Sullender, Sullender, Tamura, Trento, Trento, Trento, Venter, Waris, White, Xia, Yamaguchi, Zlateva   +50 more
core   +1 more source

First report of two consecutive respiratory syncytial virus outbreaks by the novel genotypes ON‐1 and NA‐2 in a neonatal intensive care unit

Jornal de Pediatria (Versão em Português), 2020
Objective: Respiratory syncytial virus is a pathogen frequently involved in nosocomial outbreaks. Although several studies have reported nosocomial outbreaks in neonatal intensive care units, molecular epidemiology data are scarce.
Daniella Gregoria Bomfim Prado da Silva, Flávia Jacqueline Almeida, Mariana Volpe Arnoni, Marco Aurélio Palazzi Sáfadi, Marcelo Jenne Mimica, Daniel Jarovsky, Gabriela Pereira de Almeida Rossetti, Mauricio Magalhães, Danielle Bruna Leal de Oliveira, Luciano Matsumiya Thomazelli, Thais Cristina Colmanetti, Edison Luiz Durigon, Eitan Naaman Berezin   +12 more
doaj   +3 more sources

Possible therapeutic effect of orally administered ribavirin for respiratory syncytial virus-induced acute respiratory distress syndrome in an immunocompetent patient: a case report

Journal of Medical Case Reports, 2017
Background Human respiratory syncytial virus usually causes self-limiting upper respiratory infection and occasionally causes pneumonia in immunocompromised hosts.
Byung Woo Yoon, Seung Hyeun Lee
doaj   +1 more source

The natural history of respiratory syncytial virus in a birth cohort: the influence of age and previous infection on reinfection and disease. [PDF]

, 2012
This study aimed to quantify the effect of age, time since last infection, and infection history on the rate of respiratory syncytial virus infection and the effect of age and infection history on the risk of respiratory syncytial virus disease.
Bottomley, C, Cane, PA, Medley, GF, Nokes, DJ, Ochola, R, Ohuma, EO, Okiro, EA, Sande, CJ   +7 more
core   +2 more sources

Urgent Hospitalizations Related to Viral Respiratory Disease in Children during Autumn and Winter Seasons 2022/2023

Viruses, 2023
Aim: The loosening of social distancing measures over the past two years has led to a resurgence of seasonal epidemics associated with respiratory viral infections in children.
Francesca Peri, Beatrice Lorenzon, Carolina Cason, Alessandro Amaddeo, Stefania Norbedo, Manola Comar, Egidio Barbi, Giorgio Cozzi   +7 more
doaj   +1 more source

Respiratory virus infections in hospitalized and non-hospitalized children: determinants of severe course of the disease

Journal of Infection in Developing Countries, 2022
Introduction: Viral respiratory disease constitutes a great burden worldwide mainly among children. Objective: One pursued to compare disease characteristics of children who required hospitalization from those who did not require hospitalization due to ...
Lourenço Faria Costa, Hélio Lopes da Silveira, Divina Aparecida Oliveira Queiróz, Orlando Cesar Mantese, Jonny Yokosawa   +4 more
doaj   +1 more source

A new subunit vaccine based on nucleoprotein nanoparticles confers partial clinical and virological protection in calves against bovine respiratory syncytial virus [PDF]

, 2010
Human and bovine respiratory syncytial viruses (HRSV and BRSV) are two closely related, worldwide prevalent viruses that are the leading cause of severe airway disease in children and calves, respectively.
Bernadet, Philippe, Bernard, Julie, Bernex, Florence, Castagné, Nathalie, Deplanche, Martine, Deville, Sébastien, Dubosclard, Virginie, Dubuquoy, Catherine, Durand, Guillaume, Eléouët, Jean-François, Meyer, Gilles, Petit-Camurdan, Agnès, Riffault, Sabine, Schwartz-Cornil, Isabelle, Soulestin, Marion   +14 more
core   +2 more sources

Identification of group B respiratory syncytial viruses that lack the 60-nucleotide duplication after six consecutive epidemics of total BA dominance at coastal Kenya [PDF]

, 2013
Respiratory syncytial virus BA genotype has reportedly replaced other group B genotypes worldwide. We report the observation of three group B viruses, all identical in G sequence but lacking the BA duplication, at a coastal district hospital in Kenya in ...
Agoti, Charles N., Cane, Patricia, Gitahi, Caroline W., Medley, Graham, Nokes, D. James   +4 more
core   +1 more source

Respiratory infections in children up to two years of age on prophylaxis with palivizumab

Revista Paulista de Pediatria, 2014
OBJECTIVE:To identify the viruses involved in acute respiratory tract infections and to analyze the rates of hospitalization and death in children on palivizumab prophylaxis.METHODS: Prospective cohort of 198 infants up to one year old who were born ...
Ana Isabel M. P. Monteiro, Nancy Cristina J. Bellei, Alessandra Ramos Sousa, Amélia Miyashiro N. dos Santos, Lily Yin Weckx   +4 more
doaj   +1 more source