Investigation of an outbreak of acute respiratory disease in an indigenous village in Brazil: Contribution of Influenza A(H1N1)pdm09 and human respiratory syncytial viruses. [PDF]
Cardoso AM +14 more
europepmc +1 more source
Protein Target Highlights in CASP16: Insights From the Structure Providers
ABSTRACT This article presents an in‐depth analysis of selected CASP16 targets, with a focus on their biological and functional significance. The authors highlight the most relevant features of the target proteins and discuss how well these were reproduced in the submitted predictions.
Leila T. Alexander +34 more
wiley +1 more source
Assessment of Protein Complex Predictions in CASP16: Are We Making Progress?
ABSTRACT The assessment of oligomer targets in the Critical Assessment of Structure Prediction Round 16 (CASP16) suggests that complex structure prediction remains an unsolved challenge. Even the leading groups can only predict slightly more than half of the targets to high accuracy.
Jing Zhang +9 more
wiley +1 more source
Global Epidemiology and Disease Burden of Human Parainfluenza Virus in Adults: A Systematic Review
ABSTRACT Parainfluenza virus (PIV) is a common cause of respiratory illness in children and immunocompromised adults, but little is known about its epidemiology or disease burden in the general adult population. This review evaluates published global epidemiological and disease burden for PIV in adults, including high‐risk patients (immunocompromised ...
Oliver Martyn +5 more
wiley +1 more source
Respiratory Syncytial Virus Induces RelA Release from Cytoplasmic 100-kDa NF-κB2 Complexes via a Novel Retinoic Acid-inducible Gene-I·NF-κB-inducing Kinase Signaling Pathway [PDF]
Ping Liu +3 more
openalex +1 more source
Strategic Preparedness of Broad‐Spectrum Antivirals for Rapid Response Towards Next Pandemics
Nanoengineered broad‐spectrum antivirals (BSAs) represent a transformative approach to pandemic preparedness. Unlike virus‐specific drugs requiring separate development, BSAs act across multiple viral families through nanoengineering strategies that enhance solubility, bioavailability, and host‐targeted activity.
Sanoj Rejinold N +2 more
wiley +1 more source
First-in-Human Randomized Study to Assess the Safety and Immunogenicity of an Investigational Respiratory Syncytial Virus (RSV) Vaccine Based on Chimpanzee-Adenovirus-155 Viral Vector–Expressing RSV Fusion, Nucleocapsid, and Antitermination Viral Proteins in Healthy Adults [PDF]
Paola Cicconi +14 more
openalex +1 more source
The simultaneous GzmB and PRF‐targeting EG‐FET‐type biosensor is developed for the diagnosis of respiratory diseases. The biosensor achieves femtomolar‐level detection of targets in human serum and reflects bronchial function according to cytotoxic immune activity in COPD patients. Therefore, the introduced system is proposed as an accurate, rapid, and
Seokho Jung +13 more
wiley +1 more source
Induction of Th-1 and Th-2 Responses by Respiratory Syncytial Virus Attachment Glycoprotein Is Epitope and Major Histocompatibility Complex Independent [PDF]
Anon Srikiatkhachorn +2 more
openalex +1 more source
ABSTRACT Objective To determine if routine administration of antenatal corticosteroids affects the risk of infant lower respiratory tract infection and/or childhood asthma. Design Linked population‐based cohort analysed using a regression discontinuity design, which better controls for confounding than standard observational studies.
Jennifer A. Hutcheon +8 more
wiley +1 more source

