Results 231 to 240 of about 194,896 (346)

Investigation of an outbreak of acute respiratory disease in an indigenous village in Brazil: Contribution of Influenza A(H1N1)pdm09 and human respiratory syncytial viruses. [PDF]

open access: yesPLoS One, 2019
Cardoso AM   +14 more
europepmc   +1 more source

Protein Target Highlights in CASP16: Insights From the Structure Providers

open access: yesProteins: Structure, Function, and Bioinformatics, Volume 94, Issue 1, Page 25-50, January 2026.
ABSTRACT This article presents an in‐depth analysis of selected CASP16 targets, with a focus on their biological and functional significance. The authors highlight the most relevant features of the target proteins and discuss how well these were reproduced in the submitted predictions.
Leila T. Alexander   +34 more
wiley   +1 more source

Assessment of Protein Complex Predictions in CASP16: Are We Making Progress?

open access: yesProteins: Structure, Function, and Bioinformatics, Volume 94, Issue 1, Page 106-130, January 2026.
ABSTRACT The assessment of oligomer targets in the Critical Assessment of Structure Prediction Round 16 (CASP16) suggests that complex structure prediction remains an unsolved challenge. Even the leading groups can only predict slightly more than half of the targets to high accuracy.
Jing Zhang   +9 more
wiley   +1 more source

Global Epidemiology and Disease Burden of Human Parainfluenza Virus in Adults: A Systematic Review

open access: yesReviews in Medical Virology, Volume 36, Issue 1, January 2026.
ABSTRACT Parainfluenza virus (PIV) is a common cause of respiratory illness in children and immunocompromised adults, but little is known about its epidemiology or disease burden in the general adult population. This review evaluates published global epidemiological and disease burden for PIV in adults, including high‐risk patients (immunocompromised ...
Oliver Martyn   +5 more
wiley   +1 more source

Strategic Preparedness of Broad‐Spectrum Antivirals for Rapid Response Towards Next Pandemics

open access: yesSmall Science, Volume 6, Issue 1, January 2026.
Nanoengineered broad‐spectrum antivirals (BSAs) represent a transformative approach to pandemic preparedness. Unlike virus‐specific drugs requiring separate development, BSAs act across multiple viral families through nanoengineering strategies that enhance solubility, bioavailability, and host‐targeted activity.
Sanoj Rejinold N   +2 more
wiley   +1 more source

First-in-Human Randomized Study to Assess the Safety and Immunogenicity of an Investigational Respiratory Syncytial Virus (RSV) Vaccine Based on Chimpanzee-Adenovirus-155 Viral Vector–Expressing RSV Fusion, Nucleocapsid, and Antitermination Viral Proteins in Healthy Adults [PDF]

open access: hybrid, 2019
Paola Cicconi   +14 more
openalex   +1 more source

Novel Respiratory Disease Diagnosis Tool: Development of an Au‐ReS2‐Functionalized Extended‐gate Field‐Effect Transistor‐Type Aptasensor for Simultaneous Detection of Granzyme B and Perforin

open access: yesSmall Science, Volume 6, Issue 1, January 2026.
The simultaneous GzmB and PRF‐targeting EG‐FET‐type biosensor is developed for the diagnosis of respiratory diseases. The biosensor achieves femtomolar‐level detection of targets in human serum and reflects bronchial function according to cytotoxic immune activity in COPD patients. Therefore, the introduced system is proposed as an accurate, rapid, and
Seokho Jung   +13 more
wiley   +1 more source

Antenatal Corticosteroid Administration and Childhood Respiratory Morbidity: A Regression Discontinuity Study

open access: yesBJOG: An International Journal of Obstetrics &Gynaecology, Volume 133, Issue 2, Page 263-271, January 2026.
ABSTRACT Objective To determine if routine administration of antenatal corticosteroids affects the risk of infant lower respiratory tract infection and/or childhood asthma. Design Linked population‐based cohort analysed using a regression discontinuity design, which better controls for confounding than standard observational studies.
Jennifer A. Hutcheon   +8 more
wiley   +1 more source

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