Results 171 to 180 of about 1,368,419 (314)

Cellular Responses to Mechanical Cues Across Scales: From Fundamental Insights to Translational Potential

Advanced Healthcare Materials, EarlyView.
This review examines how cellular behavior is regulated by mechanical cues transmitted through soft biomaterials, from single‐cell mechanosensing to tissue‐level adaptation. It highlights why physiological relevance, rather than model complexity alone, is critical for translational mechanobiology and introduces a scoring framework linking material ...
Mathias Polz, Manuel P. Kainz, Niklas Haider, Theresa Rienmüller, Kerstin Lenk, Rupert Kargl, Michele Terzano, Gerhard Sommer, Gerhard A. Holzapfel, Julia Fuchs   +9 more
wiley   +1 more source

The impact of traumatic injury on the respiratory system; a narrative review of injury-associated and clinically-induced mechanisms of trauma-associated pneumonia. [PDF]

Front Med (Lausanne)
Howroyd F, Weblin J, Smith FG, Duggal NA, Ahmed Z.   +4 more
europepmc   +1 more source

Gardiquimod Nanoemulsion Targets Cutaneous Leishmaniasis Lesions Reducing Systemic Toxicity and Parasite Burden

Advanced Healthcare Materials, EarlyView.
Nanoemulsion delivery of a TLR7 agonist enhances safety and promotes colocalization with Leishmania‐infected macrophages in skin lesions, enabling a ∼2‐log reduction in parasite burden. However, tissue‐level constraints and TLR‐driven regulatory feedback generate a mixed immune response that limits complete parasite clearance.
Carmen Palomino‐Cano, M. Carmen Mera‐Delgado, Esther Moreno, Esther Larrea, Lecnia Aguirre, Jonathan Miguel Zanatta, Sónia Barros‐Carvalho, Iola F. Duarte, Ricardo Silvestre, Juan M. Irache, Javier Carrión, Socorro Espuelas   +11 more
wiley   +1 more source

Association of pre-pandemic respiratory system diseases with long COVID: a population-based case-control study. [PDF]

BMC Infect Dis
Lindberg P, Lindblom S, Ljunggren G, Lee S, Kolosenko I, Runold M, Fedorowski A, Wachtler C, Piontkovskaya K, Wheelock ÅM, Carlsson AC.   +10 more
europepmc   +1 more source

Inflammation Unchecked: Concurrent Kawasaki Disease and Stevens‐Johnson Syndrome in an 18‐Month‐Old Child

Arthritis Care &Research, EarlyView.
Catherine Deffendall, Jodi Backalar, Elizabeth Acevedo Zapata, Adriana Della Porta, Lorin Bibb, Tyler Reese, Charlotte M. Brown   +6 more
wiley   +1 more source

Engineering Nanoplatforms for Alzheimer's Disease Detection via Biomolecular Corona Proteomic and Lipidomic Profiling

Advanced Healthcare Materials, EarlyView.
Engineered nanoparticles capture disease‐specific biomolecular coronas that uncover hidden molecular features of Alzheimer's disease. Combined proteomic and lipidomic analyses reveal a characteristic shift in ribosomal machinery and energy metabolism, generating a multiomic fingerprint that supports accurate disease detection and opens new ...
Antonietta Greco, Roberto Baretta, Andrea Di Fonzo, Andrea Armirotti, Stefano Cinti, Mara Mirasoli, Marco Frasconi, Claudia Corbo   +7 more
wiley   +1 more source

Breathomics to monitor interstitial lung disease associated with systemic sclerosis

ERJ Open Research
Thibault Massenet, Judith Potjewijd, Rachid Tobal, Fanny Gester, Delphine Zanella, Monique Henket, Makon-Sébastien Njock, Thibaut Dejong, Gregory Gridelet, Laurie Giltay, Françoise Guissard, Béatrice André, Clio Ribbens, Renaud Louis, Pieter Van Paassen, Julien Guiot, Pierre-Hugues Stefanuto   +16 more
doaj   +1 more source

The Toxic Effects of Hydrated Cement, Autoclaved Aerated Concrete, and Demolition Dusts on the Respiratory System in Rats. [PDF]

Toxics
Kilic M, Gokturk N, Vardi N, Ozhan O, Koca G, Turkoz MA, Biyikli M, Turgut P, Turkoz Y, Parlakpinar H, Karadag E, Colak C.   +11 more
europepmc   +1 more source

A Lightweight, 3D‐Printable, Low‐Cost, “One‐Click” Dorsal Skin Window for High‐Quality Long‐Term Multimodal Subcutaneous Tumor Imaging

Advanced Healthcare Materials, EarlyView.
An innovative, lightweight 3D‐printed skinfold chamber system is presented for long‐term intravital imaging. This affordable, biocompatible platform simplifies surgical implantation and allows high‐resolution, multimodal visualization of the tumor microenvironment for up to four weeks.
Iván Cortés Domínguez, Xabier Morales Urteaga, Maider Esparza, Lucía Grande, Ainhoa Urbiola, Cristina Ederra, Tomas Muñoz Santoro, Beatrice Pinci, Alvaro Teijeira, Carlos Ortiz de Solórzano   +9 more
wiley   +1 more source

Melatonin Inhibits COVID-19-induced Cytokine Storm by Reversing Aerobic Glycolysis in Immune Cells: A Mechanistic Analysis

Medicine in Drug Discovery, 2020
Russel J. Reiter, Ramaswamy Sharma, Qiang Ma, Alberto Dominquez-Rodriguez, Paul E. Marik, Pedro Abreu-Gonzalez   +5 more
doaj   +1 more source