Results 311 to 320 of about 24,845,891 (383)

Advances and Strategies in Enhancing mRNA Cancer Vaccines

open access: yesAdvanced Materials, EarlyView.
Messenger RNA (mRNA) vaccines offer a powerful approach for cancer immunotherapy, but their clinical impact remains limited by delivery challenges and suboptimal immune activation. This review discusses key biological barriers and design strategies—including structural optimization, immunomodulation, organ targeting delivery, and advanced nanocarriers ...
Miao Zhang   +4 more
wiley   +1 more source

A Hydro‐Expansive and Degradable Biomaterial Enabling Shape Recovery of Film‐Based Devices in Biofluids

open access: yesAdvanced Materials, EarlyView.
A chitosan‐based bio‐composite exhibits stable and strong tensile strength during volumetric expansion in body fluids, serving as a functional coating that enables a thin film‐based device to self‐flatten from its tubular shape required for catheter delivery.
Ruoxing Wang   +11 more
wiley   +1 more source

scMoresDB: A comprehensive database of single-cell multi-omics data for human respiratory system. [PDF]

open access: yesiScience
Chen K   +9 more
europepmc   +1 more source

Bacteria‐Responsive Nanostructured Drug Delivery Systems for Targeted Antimicrobial Therapy

open access: yesAdvanced Materials, EarlyView.
Bacteria‐responsive nanocarriers are designed to release antimicrobials only in the presence of infection‐specific cues. This selective activation ensures drug release precisely at the site of infection, avoiding premature or indiscriminate release, and enhancing efficacy.
Guillermo Landa   +3 more
wiley   +1 more source

An Anti‐Myd88 Peptide Synergistically Enhances the Anti‐Inflammatory Effects of Extracellular Vesicles from Naïve Umbilical Cord MSC or HEK293F CD24 Overexpressing Cells

open access: yesAdvanced Materials Interfaces, EarlyView.
This study confirms that extracellular vesicles (EVs) derived from mesenchymal stem cells (MSCs) or HEK293F cells overexpressing CD24 have anti‐inflammatory effects in macrophages and monocytes. Further loading either of these EVs with an anti‐Myd88 peptide synergistically enhanced the anti‐inflammatory effects of the EVs.
Burçin İrem Abas   +6 more
wiley   +1 more source

A Modular, Lego‐Like Microfluidic Platform for Multimodal Analysis of Biofilm Formation and Antimicrobial Response

open access: yesAdvanced Materials Interfaces, EarlyView.
A modular microfluidic platform with integrated electrodes enables real‐time, label‐free monitoring of biofilm formation, treatment, and regrowth. The system evaluates both antibiotic response and antimicrobial coating efficacy on P. aeruginosa. Its LEGO‐like design supports dynamic migration studies, offering a clinically relevant, scalable tool for ...
Deema Islayem   +9 more
wiley   +1 more source

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