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The Microbiome and the Respiratory Tract. [PDF]
Although the notion that "the normal lung is free from bacteria" remains common in textbooks, it is virtually always stated without citation or argument.
R. Dickson+3 more
semanticscholar +4 more sources
The microbiota of the respiratory tract: gatekeeper to respiratory health [PDF]
The respiratory tract is a complex organ system that is responsible for the exchange of oxygen and carbon dioxide. The human respiratory tract spans from the nostrils to the lung alveoli and is inhabited by niche-specific communities of bacteria.
W. H. Man+2 more
semanticscholar +6 more sources
Antimicrobial use Guidelines for Treatment of Respiratory Tract Disease in Dogs and Cats: Antimicrobial Guidelines Working Group of the International Society for Companion Animal Infectious Diseases [PDF]
Respiratory tract disease can be associated with primary or secondary bacterial infections in dogs and cats and is a common reason for use and potential misuse, improper use, and overuse of antimicrobials.
M. Lappin+10 more
semanticscholar +5 more sources
Decoding the Distribution of Glycan Receptors for Human-Adapted Influenza A Viruses in Ferret Respiratory Tract [PDF]
Ferrets are widely used as animal models for studying influenza A viral pathogenesis and transmissibility. Human-adapted influenza A viruses primarily target the upper respiratory tract in humans (infection of the lower respiratory tract is observed less
Aarthi Chandrasekaran+6 more
core +23 more sources
Influenza virus and SARS-CoV-2: pathogenesis and host responses in the respiratory tract
Influenza viruses cause annual epidemics and occasional pandemics of respiratory tract infections that produce a wide spectrum of clinical disease severity in humans.
T. Flerlage+4 more
semanticscholar +1 more source
Since its discovery in 2019, multiple variants of severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) have been identified. This study investigates virus spread and associated pathology in the upper and lower respiratory tracts of Syrian golden ...
F. Armando+14 more
semanticscholar +1 more source
Background Early-life respiratory tract infections might affect chronic obstructive respiratory diseases, but conclusive studies from general populations are lacking.
E. V. van Meel+68 more
semanticscholar +1 more source
Tissue resident memory T cells in the respiratory tract
Owing to their capacity to rapidly spread across the population, airborne pathogens represent a significant risk to global health. Indeed, several of the past major global pandemics have been instigated by respiratory pathogens.
Ming Z M Zheng, L. Wakim
semanticscholar +1 more source
The Diagnostic Value of Metagenomic Next–Generation Sequencing in Lower Respiratory Tract Infection
Lower respiratory tract infections are associated with high morbidity and mortality and significant clinical harm. Due to the limited ability of traditional pathogen detection methods, anti-infective therapy is mostly empirical.
Yan Zheng, X. Qiu, Ting Wang, Jie Zhang
semanticscholar +1 more source