Results 181 to 190 of about 346,283 (289)
Metabolic alterations in human pulmonary artery smooth muscle cells treated with PDGF‐BB
Animal Models and Experimental Medicine, EarlyView.Metabolic abnormalities are considered to play a key regulatory role in vascular remodeling of pulmonary arterial hypertension. We analyzed the metabolome in the culture supernatants of human pulmonary artery smooth muscle cells (PASMC) during the malignant proliferation phenotype transition via a targeted metabolomics method. Significant and extensive
Meng‐Jie Zhang +9 more
wiley +1 more source
The Aetiology of Respiratory Tract Cancer in the South African Bantu
, 1955 P. Keen +5 more
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CATARRHO-PYOGENIC AND TUBERCULOUS INFECTIONS OF THE LOWER RESPIRATORY TRACT: Being the Bolingbroke Lecture delivered before the South-West London Medical Society, June, 1925, [PDF]
, 1925 H. B. Shaw
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Animal Models and Experimental Medicine, EarlyView.Schematic diagram of the mechanism of DEK regulating RhoA activation Ezrin. Upon house dust mite (HDM) stimulation, HDM‐specific immunoglobulin E (IgE) and inflammatory factors such as interleukin 4 (IL‐4), IL‐5, IL‐13, and eosinophils increased in the nasal mucosa.
Longzhu Dai +8 more
wiley +1 more source
Antibacterial Siderophores of Pandoraea Pathogens and Their Impact on the Diseased Lung Microbiota
Angewandte Chemie, EarlyView.Genome mining of environmental and pathogenic Pandoraea species identified a conserved NRPS gene cluster and led to the discovery of novel siderophores, pandorabactins, which exert their antibacterial activity by depleting iron from competitors. Bioinformatic analysis of sputum from cystic fibrosis patients coupled with bioassays indicates that ...
Elena Herzog +8 more
wiley +2 more sources
Establishment of rat model for aspiration pneumonia and potential mechanisms
Animal Models and Experimental Medicine, EarlyView.Aspiration pneumonia was induced in Sprague Dawley rats by intratracheal instillation of hydrochloric acid (HCl, 1.5 μL/g.wt, pH = 1) followed by lipopolysaccharide (LPS, 20 μg/g.wt) after 1 h. The model reproduced hallmark features of acute lung injury, including histological lung damage, microvascular dysfunction, inflammation, hypoxemia, and ...
Hanbing Hu +7 more
wiley +1 more source
Animal Models and Experimental Medicine, EarlyView.Here, we developed a novel Chinese hamster genetic quality detection system using single‐nucleotide polymorphism (SNP) markers following this process. To obtain SNP loci, we conducted whole genome sequencing on 24 Chinese hamsters. Then, we employed an SNP loci screening criterion that we set up previously and initially screened 214 SNP loci with wide ...
Minghe Sun +14 more
wiley +1 more source
J‐SUPPORT research policy for oral mucositis associated with cancer treatment
Cancer Medicine, Volume 11, Issue 24, Page 4816-4829, December 2022., 2022 Abstract Background Oral mucositis is one of the main areas of research in supportive and palliative care of cancer patients. However, the methodology of prospective clinical trials on oral mucositis has not been established, despite its uniqueness.
Tomoya Yokota +7 more
wiley +1 more source
Annals of Neurology, EarlyView.Objective Accurate personalized survival prediction in amyotrophic lateral sclerosis is essential for effective patient care planning. This study investigates whether grey and white matter changes measured by magnetic resonance imaging can improve individual survival predictions.
Isabelle Lajoie +3 more
wiley +1 more source
Extramedullary plasmacytoma: Tumor occurrence and therapeutic concepts—A follow‐up
Cancer Medicine, Volume 11, Issue 24, Page 4743-4755, December 2022., 2022 This paper provides an overview of the extramedullary plasmacytoma cases reported between 1999 and 2021. The global patients’ cohort and the current therapy options are compared to our previous report from 1999. Abstract Background Extramedullary plasmacytoma (EMP) is a solitary tumor consisting of neoplastic plasma cells, with very little to no bone ...
Adrian Holler +7 more
wiley +1 more source