Results 191 to 200 of about 762,010 (363)

Comparison of the pathogenicity of multiple SARS‐CoV‐2 variants in mouse models

open access: yesAnimal Models and Experimental Medicine, EarlyView.
We assessed the pathogenicity of various SARS‐CoV‐2 variants using two distinct mouse models. Our findings indicated that earlier variants, including WH‐09, Beta, and Delta, exhibited greater pathogenicity than later variants. Specifically, the Omicron variant demonstrated reduced pathogenicity, characterized by a shorter disease course and diminished ...
Qi Lv   +12 more
wiley   +1 more source

Autosomal Recessive Cerebellar Ataxias: Translating Genes to Therapies

open access: yesAnnals of Neurology, EarlyView.
Autosomal recessive cerebellar ataxias are disabling neurodegenerative genetic conditions affecting balance and coordination. Advancements in genomic testing have improved diagnosis, leading to a new focus on the development of targeted precision therapeutics addressing cellular, biochemical, and genetic disease mechanisms with a resulting emphasis on ...
Brent L. Fogel   +10 more
wiley   +1 more source

Prevalence of Cystic Fibrosis Carrier Status in Chronic Rhinosinusitis Without Nasal Polyp

open access: yes
International Forum of Allergy &Rhinology, EarlyView.
Do‐Yeon Cho   +4 more
wiley   +1 more source

The Comprehensive Roadmap Toward Malaria Elimination Using Graphene and its Promising 2D Analogs

open access: yesAdvanced NanoBiomed Research, EarlyView.
Material based on a diversity of graphene with chemical properties of strong strength, high mobility, high transparency, good heat conductivity, biocompatibility, and chemical stability, advanced devices demonstrating antimalarial characteristics can be used for malaria treatment at different stages of malaria development from the injection of ...
Fangzhou He   +11 more
wiley   +1 more source

Does probiotic consumption reduce antibiotic utilization for common acute infections? A systematic review and meta-analysis. [PDF]

open access: yes, 2019
BackgroundOverall reduction of antibiotic use is a widely adopted public health goal. Given evidence that consuming probiotics reduce the incidence, duration and/or severity of certain types of common acute infections, we hypothesized that probiotics are
Connors, Grant   +9 more
core  

Roadmap to Nanomedical Applications: Nanotoxicology and In Vitro Guidelines for Lanthanide‐Doped Luminescence Nanothermometers

open access: yesAdvanced NanoBiomed Research, EarlyView.
Lanthanide‐based luminescence nanothermometry holds multifaceted potential for nanomedical applications, yet despite significant research advances, clinical translation of the engineered nanomaterials is still controversial and widely disputed. This is related to crucial nanotoxicological aspects that must be addressed at the preclinical level ...
Simona Premcheska   +2 more
wiley   +1 more source

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