Results 231 to 240 of about 2,487,129 (382)

Randomized, Double‐Blind, Placebo‐Controlled, Multiple‐Dose Studies to Assess the Safety and Efficacy of Elezanumab when Added to Standard of Care in Relapsing and Progressive Forms of Multiple Sclerosis

open access: yesAnnals of Neurology, EarlyView.
Objective Elezanumab is a monoclonal antibody that binds repulsive guidance molecule a (RGMa), an inhibitor of central nervous system regeneration after inflammation or injury. The aim was to assess the safety and efficacy of elezanumab in relapsing and progressive forms of multiple sclerosis (MS).
Bruce A.C. Cree   +6 more
wiley   +1 more source

A Combined Aptamer Pulldown‐DNAzyme Cleavage Assay for Intact Methicillin Resistant Staphylococcus aureus Cells

open access: yesAngewandte Chemie, EarlyView.
Rapid fluorescence and lateral flow assays were developed for methicillin resistant Staphylococcus aureus (SA) by combining a DNA aptamer for selective isolation and an RNA‐cleaving DNAzyme for detection of MRSA. Abstract Accurate and convenient detection of methicillin resistant Staphylococcus aureus (MRSA) plays a vital role in determining ...
Monsur Ali   +4 more
wiley   +2 more sources

Characteristics of upper and lower respiratory tract microbiota after lung transplantation. [PDF]

open access: yesRespir Res
Cai Y   +9 more
europepmc   +1 more source

Deaths associated with respiratory tract infection in childhood. [PDF]

open access: bronze, 1967
P. S. Gardner   +5 more
openalex   +1 more source

Autosomal Recessive Cerebellar Ataxias: Translating Genes to Therapies

open access: yesAnnals of Neurology, EarlyView.
Autosomal recessive cerebellar ataxias are disabling neurodegenerative genetic conditions affecting balance and coordination. Advancements in genomic testing have improved diagnosis, leading to a new focus on the development of targeted precision therapeutics addressing cellular, biochemical, and genetic disease mechanisms with a resulting emphasis on ...
Brent L. Fogel   +10 more
wiley   +1 more source

The FindMNDBiomarker Program: Protein Changes in Motor Neuron Disease/Amyotrophic Lateral Sclerosis Postmortem Tissue and Biofluids

open access: yesAnnals of Neurology, EarlyView.
Objective Biomarkers of disease pathogenesis are critically needed for amyotrophic lateral sclerosis (ALS) to facilitate diagnosis and patient stratification into appropriate therapeutic trials. Proteomic studies offer significant potential to advance this, but reproducibility across laboratories is a key component toward identifying protein changes ...
Gabrielle L. Adler   +2 more
wiley   +1 more source

Profiles of viral pathogens from individuals with acute respiratory tract infections in northern Tanzania. [PDF]

open access: yesIJID Reg
Mollel JS   +8 more
europepmc   +1 more source

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