Results 41 to 50 of about 346,283 (289)

The role of transcriptional regulators in metal ion homeostasis of Mycobacterium tuberculosis

open access: yesFrontiers in Cellular and Infection Microbiology
Metal ions are essential trace elements for all living organisms and play critical catalytic, structural, and allosteric roles in many enzymes and transcription factors.
Shuxian Wang   +6 more
doaj   +1 more source

An epidemiological survey to assess the clinical use of cephalosporins in community-acquired respiratory tract infections [PDF]

open access: yes, 2017
Background: In outpatient management of respiratory tract infections, the clinicians’ preferences always have  a broad spectrum of antibiotics as an empirical therapy.
Bhargava, Amit   +2 more
core   +2 more sources

Nirsevimab for Prevention of Hospitalizations Due to RSV in Infants [PDF]

open access: yes, 2023
Copyright \ua9 2023 Massachusetts Medical Society.BACKGROUND: The safety of the monoclonal antibody nirsevimab and the effect of nirsevimab on hospitalizations for respiratory syncytial virus (RSV)-associated lower respiratory tract infection when ...
Bangert M   +21 more
core   +1 more source

Characterization and efficacy against carbapenem-resistant Acinetobacter baumannii of a novel Friunavirus phage from sewage

open access: yesFrontiers in Cellular and Infection Microbiology
Carbapenem-resistant Acinetobacter baumannii (CRAB) has become a new threat in recent years, owing to its rapidly increasing resistance to antibiotics and new effective therapies are needed to combat this pathogen.
Zhitao Wang   +9 more
doaj   +1 more source

The effect of profiling report on antibiotic prescription for upper respiratory tract infection [PDF]

open access: yesMalaysian Family Physician, 2013
Introduction: Upper respiratory tract infection (URTI) is a common encounter in primary care and mostly viral in origin. Despite frequent reminders to primary care providers on judicious use of antibiotics for URTI, the practice is still rampant. Methods:
Mohd Fozi K, Kamaliah MN
doaj  

Respiratory Tract Microecology and Bronchopulmonary Dysplasia in Preterm Infants

open access: yesFrontiers in Pediatrics, 2021
Bronchopulmonary dysplasia (BPD) is a severe respiratory complication in preterm infants. Although the etiology and pathogenesis of BPD are complex and remain to be clarified, recent studies have reported a certain correlation between the microecological
Tong Sun, Haiyang Yu, Jianhua Fu
doaj   +1 more source

Crosstalk between gut microbiota and tumor: tumors could cause gut dysbiosis and metabolic imbalance

open access: yesMolecular Oncology, EarlyView.
In this research, we analyzed the relationship between gut microbiota and tumor. We discovered that both subcutaneous and metastatic tumors would alter the composition and metabolic function of gut microbiota. Meanwhile, fecal microbiota transplantation also indicated the anti‐tumor role of the gut microbiota, revealing the crosstalk between tumor and ...
Siyuan Zhang   +8 more
wiley   +1 more source

Romiplostim use in pregnant women with immune thrombocytopenia

open access: yesAmerican Journal of Hematology, Volume 98, Issue 1, Page 31-40, January 2023., 2023
Abstract Treatment for immune thrombocytopenia (ITP) in pregnancy is hampered by the lack of fetal safety evidence of maternally‐administered medications. The Pregnancy Surveillance Program (PSP) collected patient information from 2017–2020 for pregnancy, birth outcomes, and adverse events (AEs) for 186 women exposed to romiplostim from 20 days before ...
James B. Bussel   +7 more
wiley   +1 more source

Comparative study of adenosine 3′‐pyrophosphokinase domains of MuF polymorphic toxins

open access: yesFEBS Open Bio, EarlyView.
With the ultimate goal of understanding the association of toxin‐immunity modules to temperate phages, we characterized toxins from three prophages and examined cross‐protection from immunity proteins. The toxins exhibit adenosine 3′‐pyrophosphokinase activity and are toxic in Escherichia coli.
Eloïse M. Paulet   +6 more
wiley   +1 more source

The oxidant-antioxidant imbalance was involved in the pathogenesis of chronic rhinosinusitis with nasal polyps

open access: yesFrontiers in Immunology
BackgroundAlthough oxidative stress is involved in the pathophysiological process of chronic rhinosinusitis with nasal polyps (CRSwNP), the specific underlying mechanism is still unclear.
Jing Zhou   +17 more
doaj   +1 more source

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