Strategies to Improve the Lipophilicity of Hydrophilic Macromolecular Drugs
Advanced Healthcare Materials, EarlyView.Hydrophilic macromolecular drugs can be successfully lipidized by covalent attachment of lipids, by hydrophobic ion pairing with negatively or positively charged surfactants, and by dry or wet reverse micelle formation. Lipophilicity enhancement of hydrophilic macromolecules has several benefits including stability and bioavailability improvement ...
Sera Lindner +8 more
wiley +1 more source
Microbiota diversity and differences in the respiratory tract of children with pneumonia
Pediatric InvestigationImportance Although studies have examined the link between microbiota and airways, the understanding of microbial imbalances in the upper respiratory tract (URT) and lower respiratory tract (LRT) in pediatric pneumonia remains limited.
Dandan Ge +4 more
doaj +1 more source
[The efficacy of OM85-BV in the treatment of recurrent upper respiratory tract infection with adenoid hypertrophy and the preliminary exploration of potential therapeutic mechanism]. [PDF]
, 2020 Wenxin Chen +5 more
openalex +1 more source
Multipathogen Detection in Patients with Respiratory Tract Infection: Identification of Non-respiratory Viruses Using Multiplex Real-time Polymerase Reaction [PDF]
, 2022 Khosrow Agin +6 more
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Smart Catheters for Diagnosis, Monitoring, and Therapy
Advanced Healthcare Materials, EarlyView.This study presents a comprehensive review of smart catheters, an emerging class of medical devices that integrate embedded sensors, robotics, and communication systems, offering increased functionality and complexity to enable real‐time health monitoring, diagnostics, and treatment. Abstract This review explores smart catheters as an emerging class of
Azra Yaprak Tarman +12 more
wiley +1 more source
Impact of respiratory infection in the results of cardiac surgery in a tertiary hospital in Brazil
Brazilian Journal of Cardiovascular Surgery, 2015 Objective:To assess the impact of respiratory tract infection in the postoperative period of cardiac surgery in relation to mortality and to identify patients at higher risk of developing this complication.Methods:Cross-sectional observational study ...
Isaac Newton Guimarães Andrade +2 more
doaj +1 more source
Advanced Healthcare Materials, EarlyView.Antimicrobial peptide (AMP)‐loaded nanocarriers provide a multifunctional strategy to combat drug‐resistant Mycobacterium tuberculosis. By enhancing intracellular delivery, bypassing efflux pumps, and disrupting bacterial membranes, this platform restores phagolysosome fusion and macrophage function.
Christian S. Carnero Canales +11 more
wiley +1 more source
Microbiota regulates immune defense against respiratory tract influenza A virus infection [PDF]
, 2011 Takeshi Ichinohe +6 more
openalex +1 more source
Assessing the Clinical and Economic Benefits of Implementing Point-of-care C-Reactive Protein Test to Manage Respiratory Tract Infections: Insights From Clinician Interviews in Four European Countries [PDF]
, 2023 Enyal Lani +6 more
openalex +1 more source
Advanced Healthcare Materials, EarlyView.This review explores the evolving role of microneedle systems in psoriasis management, highlighting their potential for enhanced drug delivery, diagnosis, and disease monitoring. It also discusses unmet clinical needs for psoriasis management and technical challenges, while outlining strategic directions to advance microneedle integration into routine ...
Fatma Moawad +3 more
wiley +1 more source