ABSTRACT We describe a novel homozygous intragenic deletion in the ALS2 gene in an 8‐year‐old boy with Infantile‐onset Ascending Hereditary Spastic Paraplegia (IAHSP) and oculomotor apraxia, thereby contributing to the expanding genetic landscape of ALS2‐related disorders.
Vito Luigi Colona +15 more
wiley +1 more source
Targeted Medical Therapies for Vascular Anomalies: A Clinical Review
ABSTRACT Vascular anomalies represent a broad spectrum of disorders characterized by aberrant blood or lymphatic vessel development, which can lead to complex clinical phenotypes. Historically, vascular anomalies were classified solely on the basis of their clinical and histopathologic features.
Whitney Eng
wiley +1 more source
Modeling respiratory tract diseases for clinical translation employing conditionally reprogrammed cells. [PDF]
Daneshdoust D +4 more
europepmc +1 more source
Systemic Foot-and-Mouth Disease Vaccination in Cattle Promotes Specific Antibody-Secreting Cells at the Respiratory Tract and Triggers Local Anamnestic Responses upon Aerosol Infection [PDF]
J. Pega +9 more
openalex +1 more source
ABSTRACT Background Chronic rhinosinusitis with nasal polyps (CRSwNP) is a type 2 inflammatory disease often associated with asthma. The global airway hypothesis suggests bidirectional inflammatory interactions between upper and lower airways. Mepolizumab, an anti–IL‐5 therapy, treats conditions systemically, while functional endoscopic sinus surgery ...
Jens Tidemandsen +9 more
wiley +1 more source
The Redox Properties of Polyphenols and Their Role in ROS Generation for Biomedical Applications
The dual redox nature of polyphenols enables antioxidant activity and controlled reactive oxygen species (ROS) generation. This review details the biomedical applications of polyphenols in materials such as nanoparticles, coatings, and hydrogels for antimicrobial, tissue regeneration, and cancer therapies.
Jose Bolaños‐Cardet +7 more
wiley +2 more sources
The Relationship between Fine Particle Matter (PM2.5) Exposure and Upper Respiratory Tract Diseases. [PDF]
Zaręba Ł +6 more
europepmc +1 more source
Upper Respiratory Tract Diseases in Athletes in Different Sports Disciplines. [PDF]
Gałązka-Franta A +3 more
europepmc +1 more source
Early Adaptive Immune Responses in the Respiratory Tract of Foot-and-Mouth Disease Virus-Infected Cattle [PDF]
J. Pega +11 more
openalex +1 more source

