Results 241 to 250 of about 885,071 (345)

Efficacy, Safety, Pharmacokinetics, and Immunogenicity of ABBV‐154 in Adults With Glucocorticoid‐Dependent Polymyalgia Rheumatica: A Phase 2, Randomized, Double‐Blind, Placebo‐Controlled Trial

Arthritis &Rheumatology, EarlyView.
Objective An unmet need exists for glucocorticoid‐sparing treatments for patients with polymyalgia rheumatica (PMR). The antibody‐drug conjugate ABBV‐154 comprises adalimumab conjugated to a glucocorticoid receptor modulator. We evaluated ABBV‐154 versus placebo in patients with glucocorticoid‐dependent PMR.
Robert F. Spiera, Valerie Devauchelle‐Pensec, Claire E. Owen, Federico Díaz‐González, Tsutomu Takeuchi, Edit Drescher, Jaclyn Anderson, Dilek Arikan, Ronilda D'Cunha, Julie Parmentier, Denise T. Kruzikas, Weihan Zhao, Yang Yang, Karen Stellpflug, Frank Buttgereit   +14 more
wiley   +1 more source

Long‐Term Safety and Efficacy of Mepolizumab in Eosinophilic Granulomatosis With Polyangiitis

Arthritis &Rheumatology, EarlyView.
Objective Eosinophilic granulomatosis with polyangiitis (EGPA) is a rare, relapsing, inflammatory disease. Management of EGPA predominantly relies on oral corticosteroids (OCS), which are associated with many adverse effects. The phase 3 MIRRA trial demonstrated efficacy and safety of mepolizumab, anti‐interleukin‐5 biologic, for EGPA.
Michael E. Wechsler, Jared Silver, Gerhard Wolff, Robert G. Price, Rejina Verghis, Peter F. Weller, Peter A. Merkel, Paneez Khoury, on behalf of the EGPA Mepolizumab Open‐Label Extension study group, Arnaud Bourdin, Pascal Chanez, Anoop Chauhan, Vincent Cottin, Gerald Gleich, Berhnard Hellmich, Tomonori Ishii, David Jayne, Jean‐Emmanuel Kahn, Peter Kern, Nader Khalidi, Ina Koetter, Carol Langford, Amy Markezich, Paul Monach, Shamsa Naveed, Peter Oelzner, Kenneth Pinna, Xavier Puechal, Emory H. Robinette, Florence Roufosse, Reinhard Voll, Andrew Schafer, Kaharu Sumino, Masami Taniguchi, Phillip Lieberman   +34 more
wiley   +1 more source

Lower Respiratory Tract Diseases Caused by Common Respiratory Viruses among Stem Cell Transplantation Recipients: A Single Center Experience in Korea. [PDF]

Yonsei Med J, 2017
Hong KW, Choi SM, Lee DG, Cho SY, Lee HJ, Choi JK, Kim SH, Park SH, Choi JH, Yoo JH, Lee JW.   +10 more
europepmc   +1 more source

Diseases of the Respiratory Tract

, 2014
openaire   +2 more sources

Respiratory and Alimentary Tract Diseases [PDF]

Archives of Disease in Childhood, 1987
openaire   +2 more sources

Expert perspective: How, When, and Why to Potentially Stop Anti‐resorptive Drugs in Osteoporosis

Arthritis &Rheumatology, Accepted Article.
Osteoporosis is a chronic disease and anti‐resorptive treatments are often continued for many years. Despite their established efficacy in reducing fracture risk, the most commonly used anti‐resorptive treatments bisphosphonates and denosumab have short and longer term risks that, coupled with their benefits and other unique characteristics, influence ...
Giovanni Adami, Kenneth G Saag
wiley   +1 more source

Prevalence of Chlamydia pneumoniae in Acute Respiratory Tract Infection and Detection of Anti-Chlamydia pneumoniae-speciflc lgE in Japanese Children with Reactive Airway Disease.

, 2001
Shigeru Ikezawa
openalex   +2 more sources

Time‐dependent effect of prophylactic trimethoprim‐sulfamethoxazole on the incidence of serious infections in ANCA‐associated vasculitis: A target trial emulation study

Arthritis &Rheumatology, Accepted Article.
Objectives To investigate the effect of prophylactic trimethoprim‐sulfamethoxazole (TMP‐SMX) on the incidence of serious infections in patients with anti‐neutrophil cytoplasmic antibody‐associated vasculitis (AAV). Methods This multicenter cohort study designed to emulate a target trial studied 296 patients with AAV treated with rituximab or ...
Yun Kyu Kim, Jeffrey R Curtis, Se Rim Choi, Jina Yeo, Min Jung Kim, Yun Jong Lee, Eun Bong Lee, Jun Won Park   +7 more
wiley   +1 more source

Breastfeeding decreases hospitalizations for lower respiratory tract disease in infancy: a meta-analysis

, 2001
Virginia R. Galton Bachrach, Eleanor Bimla Schwarz, Lela Bachrach   +2 more
openalex   +1 more source

Development of a potent respiratory syncytial virus-specific monoclonal antibody for the prevention of serious lower respiratory tract disease in infants

, 2002
J YOUNG
openalex   +1 more source