Results 61 to 70 of about 882,034 (305)
Summary: Ambient air pollutants are health hazards to children. This study comprised 773,504 emergency department visits (EDVs) at 0–14 years of age with respiratory diseases in southern China.
Miao He+4 more
doaj
Two SOX11 variants cause Coffin–Siris syndrome with a new feature of sensorineural hearing loss
Abstract Coffin‐Siris syndrome (CSS, OMIM#135900) is a rare congenital disorder associated with neurodevelopmental and dysmorphic features. The primary cause of CSS is pathogenic variants in any of 9 BAF chromatin‐remodeling complex encoding genes or the genes SOX11 and PHF6. Herein, we performed whole‐exome sequencing (WES) and a series of analyses of
Qiuquan Wang+5 more
wiley +1 more source
Abstract Objectives Intravenous immunoglobulin (IVIg) is an effective treatment for Guillain–Barré syndrome (GBS), but recovery varies between patients. This study aims to evaluate the pharmacokinetics (PK) and pharmacodynamics (PD) of a single and a second IVIg dose (SID) in patients with GBS.
Sander J. van Tilburg+7 more
wiley +1 more source
The Gut Microbiota and Respiratory Diseases: New Evidence
Human body surfaces, such as the skin, intestines, and respiratory and urogenital tracts, are colonized by a large number of microorganisms, including bacteria, fungi, and viruses, with the gut being the most densely and extensively colonized organ.
Chunxi Li+4 more
semanticscholar +1 more source
ADAPT NXT: Fixed Cycles or Every‐Other‐Week IV Efgartigimod in Generalized Myasthenia Gravis
ABSTRACT Objective This phase 3b, open‐label, randomized ADAPT NXT study investigated the efficacy, safety, and tolerability of efgartigimod administered in either a fixed cycles dosing regimen (3 cycles of 4 once‐weekly infusions, with 4 weeks between cycles) or a cycle followed by every‐other‐week (Q2W) dosing.
Ali A. Habib+16 more
wiley +1 more source
Topical antibacterial therapy in the practice of otolaryngologist
The article highlights the problem of treating the most urgent inflammatory diseases of the upper respiratory tract, namely acute rhinosinusitis and acute otitis media in adults and children.
V. M. Svistushkin, E. A. Shevchik
doaj +1 more source
The prebiotics and probiotics market is constantly growing due to the positive effects of its consumption on human health, which extends beyond the digestive system.
M. Bustamante+5 more
semanticscholar +1 more source
Objective This work aimed to evaluate the pharmacokinetics, efficacy, and safety of upadacitinib, an oral selective JAK inhibitor, in pediatric patients with polyarticular‐course juvenile idiopathic arthritis (pcJIA). Methods In an open‐label, phase 1 study (SELECT‐YOUTH), enrolled patients, aged 2 to <18 years with pcJIA, received body weight–based ...
Hermine I. Brunner+12 more
wiley +1 more source
Application of Imupret in the Complex Treatment of Chronic Glomerulonephritis in Children
The article presents data on clinical efficacy, tolerability and safety of immunoprophylaxis of acute respiratory viral infections and exacerbation of episodes of acute inflammatory diseases of the upper respiratory tract in children with chronic ...
D.D. Ivanov, S.V. Kushnirenko
doaj +1 more source
Probiotics in the comprehensive prevention of respiratory infections in children
Viral infections of the respiratory tract are the most common cause of infectious diseases, especially in children. In most cases, especially when the upper respiratory tract is affected, acute respiratory viral infections are mild to moderate and often ...
S. V. Nikolaeva+3 more
doaj +1 more source