Results 61 to 70 of about 1,108,007 (376)
From omics to AI—mapping the pathogenic pathways in type 2 diabetes
FEBS Letters, EarlyView.Integrating multi‐omics data with AI‐based modelling (unsupervised and supervised machine learning) identify optimal patient clusters, informing AI‐driven accurate risk stratification. Digital twins simulate individual trajectories in real time, guiding precision medicine by matching patients to targeted therapies.
Siobhán O'Sullivan +2 more
wiley +1 more source
ANTIBIOTIC THERAPY FOR ACUTE UPPER RESPIRATORY TRACT DISEASES
Медицинский совет, 2017 The article highlights the main differential diagnostic criteria for acute respiratory viral infection, acute tonsillopharyngitis and acute rhinosinusitis, and the differences in the clinical course of viral and bacterial forms of the diseases.
M. L. Derbeneva, A. L. Guseva
doaj +1 more source
Modifiable risk factors associated with bronchiolitis [PDF]
, 2017 Background: We sought to clarify possibly modifiable risk factors related to pollution responsible for acute bronchiolitis in hospitalized infants. Methods: For this observational study, we recruited 213 consecutive infants with bronchiolitis (cases ...
Alessandroni, Claudia +13 more
core +1 more source
A working model for cytoplasmic assembly of H/ACA snoRNPs
FEBS Letters, EarlyView.Dyskerin is the component of nuclear H/ACA ribonucleoproteins (RNPs) endowed with pseudouridine synthase catalytic activity. Two isoforms of human dyskerin have been characterized: the abundant Iso1, mainly nuclear, and the shorter Iso3, mainly cytoplasmic but occasionally imported into nuclei.
Alberto Angrisani, Maria Furia
wiley +1 more source
Molecular Oncology, EarlyView.Nuclear prothymosin α inhibits epithelial‐mesenchymal transition (EMT) in lung cancer by increasing Smad7 acetylation and competing with Smad2 for binding to SNAI1, TWIST1, and ZEB1 promoters. In early‐stage cancer, ProT suppresses TGF‐β‐induced EMT, while its loss in the nucleus in late‐stage cancer leads to enhanced EMT and poor prognosis.
Liyun Chen +12 more
wiley +1 more source
Frontiers in Microbiology, 2014 Previously unknown or unexpected pathogens may be responsible for that proportion of respiratory diseases in which a causative agent cannot be identified. The application of broad-spectrum, sequence independent virus discovery techniques may be useful to
Marta eCanuti +13 more
doaj +1 more source
Viruses associated with pneumonia in adults. [PDF]
, 2012 Viral pneumonia, which is typically associated with disease in childhood, is increasingly recognized as causing problems in adults. Certain viruses, such as influenza virus, can attack fully immunocompetent adults, but many viruses take advantage of more-
Cesario, Thomas C
core +1 more source
FEBS Open Bio, EarlyView.In this research, a rat model of asthma was created using OVA, and polydatin served as an intervention. By inhibiting ferroautophagy mediated by NCOA4 and averting ferroptosis, polydatin has been demonstrated to reduce asthma. This work presents new ideas for investigating the mechanism of polydatin's ability to alleviate asthma, in addition to ...
Wei Li +5 more
wiley +1 more source
Application of Imupret in the Complex Treatment of Chronic Glomerulonephritis in Children
Počki, 2014 The article presents data on clinical efficacy, tolerability and safety of immunoprophylaxis of acute respiratory viral infections and exacerbation of episodes of acute inflammatory diseases of the upper respiratory tract in children with chronic ...
D.D. Ivanov, S.V. Kushnirenko
doaj +1 more source
UPPER RESPIRATORY TRACT INFECTIONS IN CHILDREN: FROM CASE HISTORY TO MANAGEMENT [PDF]
, 2015 Respiratory tract infections are the most common diseases in childhood. The respiratory tract, widely branched system of ducts, is particularly exposed to the action of microorganisms transmitted by air from here the high frequency of infections they ...
BRANCATO, Anna +12 more
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