Results 201 to 210 of about 570,791 (297)

Views of Spanish primary care professionals on respiratory tract infection testing: a qualitative study. [PDF]

BMJ Open
Moragas A, Cots JM, Llor C.
europepmc   +1 more source

A four-gene signature from blood to exclude bacterial etiology of lower respiratory tract infection in adults. [PDF]

Nat Commun
Falsey AR, Peterson DR, Walsh EE, Bhattacharya S, Baran AM, Chu C, Branche AR, Croft DP, Peasley M, Corbett AM, Ashton J, Mariani TJ.   +11 more
europepmc   +1 more source

SV2A expression in blood cells as a possible biomarker candidate for levetiracetam treatment response

Epilepsia, EarlyView.
Abstract Objective This study was undertaken to evaluate whether synaptic vesicle protein 2A (SV2A) expression on peripheral immune cells predicts treatment response to levetiracetam in epilepsy. Methods High‐dimensional flow cytometry was used to prospectively assess SV2A expression on immune cells from levetiracetam responders, nonresponders, and ...
Johannes Lang, Mathias Linnerbauer, Jeanne Cuny, Veit Rothhammer, Hajo Hamer   +4 more
wiley   +1 more source

Secondary Haemophagocytic Lymphohistiocytosis Triggered by Adult-Onset Still's Disease in Mid-trimester Pregnancy Initially Presenting as an Upper Respiratory Tract Infection: A Case Report. [PDF]

Cureus
Hiramoti M, Ruthi NF.
europepmc   +1 more source

Chronic Upper Respiratory Tract Infections [PDF]

Proceedings of the Royal Society of Medicine, 1951
openaire   +2 more sources

Soticlestat as an adjunctive therapy in children and young adults with Dravet syndrome

Epilepsia, EarlyView.
Overview of the phase 3 trial evaluating soticlestat as adjunctive therapy in children and young adults with Dravet syndrome. Abstract Objective This study evaluated the efficacy, safety, and tolerability of soticlestat as adjunctive therapy in children and young adults with Dravet syndrome (DS).
Joseph Sullivan, Kette Valente, Vicente Villanueva, Adam Strzelczyk, Rima Nabbout, Eiji Nakagawa, Yuehua Zhang, Marta Zolnowska, Yasir Khan, Cheng Dong, Samuel Hsiao, Sarah I. Sheikh, Philipp von Rosenstiel, Mahnaz Asgharnejad, Venkatesha Murthy   +14 more
wiley   +1 more source

Host gene expression in the Nasopharynx can discriminate microbiologically confirmed viral and bacterial lower respiratory tract infection. [PDF]

J Clin Transl Sci
Tillekeratne LG, O'Grady N, Iglesias-Ussel MD, Anderson J, Brown A, Obale A, Nix C, Bodinayake CK, Nagahawatte A, Rolfe R, Woodhouse EW, Wijayaratne GB, Weerasinghe S, Dilshan UHBY, Gamage J, Kurukulasooriya R, Premamali M, Jayasinghearachchi HS, Nicholson BP, Ko ER, Tsalik EL, McClain MT, Myers RA, Woods CW, Burke TW.   +24 more
europepmc   +1 more source

An n‐of‐1 gene‐directed drug repurposing trial for an ultrarare genetic condition

Epilepsia, EarlyView.
Abstract Objective Gain‐of‐function (GoF) variants in the KCNC1 potassium channel subunit gene (Kv3.1) cause motor/cognitive delays and hypotonia and have been associated with seizures. Fluoxetine has inhibitory effects on Kv3.1. However, open‐label nonrandomized administration is insufficient to guide clinical decision‐making in ultrarare conditions ...
Vedika Jha, Christina Tsetsos, Mark Bedford, Gregory Costain, Sunita Vohra, Juan Pablo Diaz Martinez, Elise Heon, Jacob Vorstman, Carolina Gorodetsky, Ajoy Vincent, Jesiqua Rapley, Lori Anderson, Evdokia Anagnostou, Danielle A. Baribeau   +13 more
wiley   +1 more source

Protocolized antimicrobial stewardship following filmarray pneumonia plus panel testing in mechanically ventilated patients with severe lower respiratory tract infection. [PDF]

Sci Rep
Cano S, Clari MÁ, Albert E, Liñan J, Juan M, Olea B, Carbonell N, Navarro D.   +7 more
europepmc   +1 more source

Intestinal microbiome alterations in pediatric epilepsy: Implications for seizures and therapeutic approaches

Epilepsia Open, EarlyView.
Abstract The intestinal microbiome plays a pivotal role in maintaining host health through its involvement in gastrointestinal, immune, and central nervous system (CNS) functions. Recent evidence underscores the bidirectional communication between the microbiota, the gut, and the brain and the impact of this axis on neurological diseases, including ...
Teresa Ravizza, Greta Volpedo, Antonella Riva, Pasquale Striano, Annamaria Vezzani   +4 more
wiley   +1 more source