Results 41 to 50 of about 2,870,899 (307)

CD25(+) Natural Regulatory T Cells Are Critical in Limiting Innate and Adaptive Immunity and Resolving Disease following Respiratory Syncytial Virus Infection [PDF]

, 2010
Regulatory CD4(+) T cells have been shown to be important in limiting immune responses, but their role in respiratory viral infections has received little attention.
Harker, JA, Johansson, C, Cecilia Johansson, Tregoning, John S, Jürgen Schwarze, Atabani, Sowsan F, Lee, Debbie C P, Atabani, SF, Lee, DC, Harker, James A E, Peter J. M. Openshaw, Schwarze, J, Harker, JAE, James A. E. Harker, Openshaw, Peter J M, Tregoning, JS, Lee, DCP, Johansson, Cecilia, John S. Tregoning, Openshaw, PJ, Schwarze, Jürgen, Openshaw, PJM, Debbie C. P. Lee, Sowsan F. Atabani   +23 more
core   +1 more source

Parental and household smoking and the increased risk of bronchitis, bronchiolitis and other lower respiratory infections in infancy: systematic review and meta-analysis [PDF]

, 2011
Background: Passive smoke exposure increases the risk of lower respiratory infection (LRI) in infants, but the extensive literature on this association has not been systematically reviewed for nearly ten years.
Hashim, Ahmed, Jones, Laura L; id_orcid, Leonardi-Bee, J, Ahmed Hashim, Derek G Cook, Britton, J, John Britton, Laura L Jones, Britton John, McKeever Tricia, Cook, Derek G, Leonardi-Bee, Jo, Jones, LL, Cook Derek G, McKeever, Tricia, Britton, John, Leonardi-Bee Jo, Hashim, A, Jo Leonardi-Bee, McKeever, T, Cook, DG, Hashim Ahmed, Jones Laura L, Tricia McKeever   +23 more
core   +2 more sources

Investigation of human bocavirus in pediatric patients with respiratory tract infection [PDF]

, 2020
Introduction: Human bocavirus (HBoV) is a linear single-stranded DNA virus belonging to the Parvoviridae family. This study aimed to investigate the incidence of HBoV and co-infections in pediatric patients with symptoms of viral respiratory tract ...
Ali Agacfidan, Nuran Karabulut, Sevim Mese, Alaçam, Sema, Ayfer Bakir, Somer, Ayper, Bakir, Ayfer, Sema Alacam, Ayper Somer, Karabulut, Nuran, Agacfidan, Ali, Mese, Sevim   +11 more
core   +1 more source

Iron and vitamin D3 levels in infants admitted with chest infection: A hospital-based study

Zanco Journal of Medical Sciences, 2020
Background and objective: Acute lower respiratory tract infection is one of the major causes of mortality and morbidity in children under five years of age, with many etiologies suggested to be among its predisposing risk factors.
Nevine Jasim Mohammad, Sherwan Rahman Sulaiman   +1 more
doaj   +1 more source

Urinary ATP as an indicator of infection and inflammation of the urinary tract in patients with lower urinary tract symptoms [PDF]

, 2015
BACKGROUND: Adenosine-5'-triphosphate (ATP) is a neurotransmitter and inflammatory cytokine implicated in the pathophysiology of lower urinary tract disease. ATP additionally reflects microbial biomass thus has potential as a surrogate marker of urinary
Baio, Gianluca, Malone-Lee, James, De Iorio, Maria, Sathiananamoorthy, Sanchutha, Horsley, Harry, Wildman, Scott S.P., Rohn, Jennifer L, Gill, Kiren, Khasriya, Rajvinder, Wildman, Scott, Kupelian, Anthony S   +10 more
core   +1 more source

Respiratory viral infection`s frequency and clinical outcome in symptomatic children with cancer: A single center experience from a middle-income country

The Turkish Journal of Pediatrics, 2018
In developing countries, acute respiratory tract infections are a significant cause of morbidity and mortality in children, particularly in pediatric cancer patients. A majority of these illnesses are precipitated by viral infections.
Sema Büyükkapu-Bay, Rejin Kebudi, Ömer Görgün, Sevim Meşe, Bülent Zülfikar, Selim Badur   +5 more
doaj   +1 more source

Treatment of acute respiratory infection in adults: results of a multicenter randomized double-blind placebo-controlled clinical trial

Лечащий Врач, 2021
The results of a multicenter randomized double-blind placebo-controlled clinical trial in parallel groups carried out in 2012–2015 aimed to reveal the efficacy and safety of the antiviral drug ergoferon in the treatment of acute respiratory tract ...
M. P. Kostinov, R. F. Khamitov, A. P. Babkin, E. S. Minina, B. Ya. Bart, M. P. Mikhailusova, M. E. Yanovskaya, A. O. Sherenkov, D. V. Petrov, D. N. Alpenidze, Yu. S. Shapovalova, M. V. Chernogorova, E. F. Pavlysh, R. T. Sardinov   +13 more
doaj   +1 more source

Duration of shedding of respiratory syncytial virus in a community study of Kenyan children [PDF]

, 2010
Background: Our understanding of the transmission dynamics of respiratory syncytial virus (RSV) infection will be better informed with improved data on the patterns of shedding in cases not limited only to hospital admissions.
Lisa J White, Medley, GF, Nokes, D. James, Nokes, DJ, Ngama, Mwanajuma, Ngama, M, Patricia A Cane, White, Lisa, D James Nokes, White, L. J., Okiro, E. A., Emelda A Okiro, Medley, Graham, Graham F Medley, Cane, Patricia, Okiro, EA, Mwanajuma Ngama, Cane, PA   +17 more
core   +2 more sources

An epithelial GPR35 isoform supports tumor‐associated transcriptional and metabolic phenotypes

FEBS Letters, EarlyView.
GPR35 generates two functionally distinct isoforms with previously unresolved roles. GPR35‐short mediates immune‐cell chemotaxis, while GPR35‐long is enriched in colorectal cancer epithelium, where it supports increased metabolism, proliferation, and tumor‐associated transcriptional programs.
Jørgen D. Rønneberg, Martine Hjeltnes, Josephine Krieger, Joshua E. Elias, Maria Stensland, Kristian Holm, Xiaojun Jiang, Chuki Khangsar, Tuula A. Nyman, Arthur Kaser, Johannes R. Hov, Tom H. Karlsen, Nicole C. Kaneider, Frode L. Jahnsen, Georg Schneditz   +14 more
wiley   +1 more source

PANoptosis in the pathogenesis of myelodysplastic syndromes

Molecular Oncology, EarlyView.
PANoptosis, a combination of three types of programmed cell death, is mediated by a large protein complex called a PANoptosome. In healthy bone marrow hematopoietic cells, PANoptosis is restricted by inhibitory signaling. In MDS, bone marrow cells become sensitive to the PANoptotic stimuli due to the aberrant inactivation of inhibitory signaling or ...
Rohit Thalla, Jyoti Lamichhane, Cameron Lewis, Peter Breslin, Jiwang Zhang   +4 more
wiley   +1 more source