In orden to determine the frequency of bacterial pathogens in the respiratory tract of children between the ages of 0 – 11 years old who attend the emergency service in the Pediatrics ward at the Autonomous Hospital Antonio Patricio de Alcalá in Cumaná ...
Militza Guzmán L+3 more
doaj
Physical exercise and cardiac death due to pneumonia in male teenagers [Iznenadna smrt zbog upalće pluća za vrijeme tjelovježbe u trojice mladića] [PDF]
From 1998 to 2008 we noticed 3 cardiac deaths in male teenagers aged 18-19 during or after physical exercise. The first was working at the site recreatively, the second was engaged in soccer recreatively and the third was professional soccer player.
Duraković, Lejla+3 more
core
Respiratory virus mRNA vaccines: mRNA Design, clinical studies, and future challenges
Abstract Respiratory infectious diseases frequently erupt on a global scale, with RNA viruses, such as SARS‐CoV‐2, RSV, and influenza viruses, posing challenges to vaccine development due to their high mutation rates. Traditional vaccine development cycles are lengthy and struggle to keep pace with rapidly evolving viruses, whereas messenger RNA (mRNA)
Linlin Zheng, Han Feng
wiley +1 more source
Comparison of the pathogenicity of multiple SARS‐CoV‐2 variants in mouse models
We assessed the pathogenicity of various SARS‐CoV‐2 variants using two distinct mouse models. Our findings indicated that earlier variants, including WH‐09, Beta, and Delta, exhibited greater pathogenicity than later variants. Specifically, the Omicron variant demonstrated reduced pathogenicity, characterized by a shorter disease course and diminished ...
Qi Lv+12 more
wiley +1 more source
Cell-Mediated Immunity after Bacterial Infection of the Lower Respiratory Tract [PDF]
J. Robert Cantey+4 more
openalex +1 more source
Diosgenin ameliorates silica‐induced tuberculosis in rats
Silicosis increases susceptibility to tuberculosis due to impaired macrophage function and oxidative stress. This study demonstrates that diosgenin, a steroidal saponin, significantly inhibits Mycobacterium smegmatis (IC₅₀ = 0.006 μg/mL), reduces lung fibrosis, and restores antioxidant enzyme levels (↑SOD, ↑CAT, ↓MDA) in silica‐exposed rats ...
Williams Asamoah Adu+5 more
wiley +1 more source
Synergistic Effect in Viral-Bacterial Infection: Combined Infection of the Murine Respiratory Tract with Sendai Virus and Pasteurella pneumotropica [PDF]
George J. Jakab, Elliot C. Dick
openalex +1 more source
Engineered Hydrogels Revolutionize Locoregional Cancer Immunotherapy
This review systematically summarizes the latest research progress on injectable hydrogels in cancer immunotherapy, highlighting their unique advantages in precise immune activation, local drug‐controlled release, and immune microenvironment remodeling. These features provide innovative solutions to overcome the bottlenecks of systemic side effects and
Jiyong Wei+3 more
wiley +1 more source
Research progress on microecology and childhood respiratory infections via the lung-gut axis
Respiratory tract infections (RTIs) are a complex global public health challenge, with children being the most affected population. Affected children often exhibit gut microbiota-related symptoms, such as dysbiosis, feeding difficulties, and ...
Zhixuan He+3 more
doaj +1 more source
Activation of Alveolar Macrophages after Lower Respiratory Tract Infection [PDF]
James D. Johnson+3 more
openalex +1 more source