Results 181 to 190 of about 910,981 (387)
Prescription drug use in breastfeeding mothers and infant exposure: A register‐based cohort study
British Journal of Clinical Pharmacology, EarlyView.Abstract Aims
Breast milk is the optimal infant nutrition; however, many infants may be exposed to prescription drugs if used by their mothers during breastfeeding. The aim of this study was to evaluate the prevalence and patterns of prescription drug use among breastfeeding mothers and to assess the availability of relative infant dose information for Ditte Resendal Gotfredsen, Ida M. Heerfordt, Christoffer Storm Baden, Henrik Horwitz, Christina Gade, Jon Trærup Andersen +5 morewiley +1 more sourceDevelopment of the Gut Microbial Immune and Epithelial Cellular System (GutMICS) to Investigate the Immunological Role of Gut Anaerobes
Biotechnology and Bioengineering, EarlyView.Abstract
The gut microbiota plays an essential role in host health by regulating gut barrier function and immune system homeostasis. However, research into the physiological and immunological functions of the gut microbiota using In Vitro models that mimic the immune environment of the gut remains limited. Herein, we developed the Gut Microbial Immune &Seo‐Young Kwon, Sung‐Hyun Jo, Joonha Park, Ji‐Hyeon Park, Ye‐Rim Kim, Ji‐Hyun Baek, Min‐Gyu Kim, Bo‐Gyeong Choi, Na Youn Hong, Hee Kyoung Jung, Hee‐Wook Ryu, Jessie S. Jeon, Yun‐Gon Kim +12 morewiley +1 more sourceDeciphering the skeletal interoceptive circuitry to control bone homeostasis
BMEMat, EarlyView.This review introduces the skeletal interoceptive circuitry, covering the ascending signals from bone tissues to the brain (sensors), the central neural circuits that integrate this information and dispatch commands (CPU), and the descending pathways that regulate bone homeostasis (effectors).Yefeng Wu, Jiusi Guo, Zhen Chen, Fengwei Zhang, Billy Kwok Chong Chow, Zhuofan Chen, Kelvin Wai‐Kwok Yeung, Wei Qiao +7 morewiley +1 more sourceAn open‐label, single‐arm, multicenter, phase II trial of bireociclib as monotherapy for heavily pretreated HR‐positive, HER2‐negative advanced breast cancer patients: BRIGHT‐1 trial
Cancer Communications, EarlyView.Abstract Background
Bireociclib (XZP‐3287) is a novel selective cyclin‐dependent kinase 4 and 6 (CDK4/6) inhibitor, with a favorable safety profile demonstrated in preclinical and phase I studies. BRIGHT‐1 aimed to further explore the efficacy and safety of bireociclib monotherapy in patients with locally advanced, recurrent or metastatic, hormone ...Jiayu Wang, Qingyuan Zhang, Tao Sun, Huiping Li, Ying Cheng, Zhongsheng Tong, Huihui Li, Wei Li, Jingfen Wang, Yuee Teng, Xinhong Wu, Jing Cheng, Zhendong Chen, Zhengqiu Zhu, Li Wang, Mingming Liu, Xianghui Duan, Lingmei Xu, Binghe Xu +18 morewiley +1 more sourcePromising Prodiginins Biological Activities
Chemistry &Biodiversity, EarlyView.ABSTRACT
Prodiginins are a large family of at least 34 pyrrolic compounds, including the well‐studied red pigment prodigiosin. Prodiginins are produced by several microorganisms displaying broad biological activities, including antimicrobial, antiviral, antiparasitic, antiproliferative, and immunosuppressive activities.María F. Ladetto, Melisa E. Gantner, Boris E. Rodenak‐Kladniew, Santiago Rodriguez, María L. Cuestas, Alan Talevi, Guillermo R. Castro +6 morewiley +1 more sourceMortality, morbidity, and hospitalisations due to influenza lower respiratory tract infections, 2017: an analysis for the Global Burden of Disease Study 2017
The Lancet Respiratory Medicine, 2019 C. Troeger, B. Blacker, I. Khalil, Stephanie R M Zimsen, Samuel B. Albertson, D. Abate, Jemal Abdela, Tara Ballav Adhikari, S. Aghayan, S. Agrawal, A. Ahmadi, Amani Nidhal Aichour, Ibtihel Aichour, Miloud Taki Eddine Aichour, A. Al-Eyadhy, Rajaa Al-Raddadi, Fares Alahdab, K. Alene, S. Aljunid, N. Alvis-Guzmán, N. Anber, Mina Anjomshoa, C. Antonio, O. Aremu, Hagos T. Atalay, S. Atique, E. Attia, Euripide Avokpaho, A. Awasthi, A. Babazadeh, H. Badali, A. Badawi, J. Banoub, A. Barać, Q. Bassat, Neeraj Bedi, A. Belachew, D. Bennett, Krittika Bhattacharyya, Z. Bhutta, Ali Bijani, F. Carvalho, C. Castañeda-Orjuela, D. Christopher, L. Dandona, R. Dandona, Anh Kim Dang, A. Daryani, M. G. Degefa, F. M. Demeke, M. Dhimal, Shirin Djalalinia, D. Doku, M. Dubey, E. Dubljanin, Eyasu Ejeta Duken, Dumessa Edessa, M. El Sayed Zaki, H. Fakhim, E. Fernandes, F. Fischer, L. Flor, Kyle Foreman, Teklu Gebrehiwo Gebremichael, D. Geremew, K. Ghadiri, A. Goulart, Jingwen Guo, G. H. Ha, G. B. Hailu, Arvin Haj-Mirzaian, A. Haj-Mirzaian, S. Hamidi, H. Y. Hassen, C. L. Hoang, N. Horita, M. Hostiuc, S. Irvani, Ravi Prakash Jha, J. Jonas, Amaha Kahsay, A. Karch, A. Kasaeian, T. Kassa, A. Kefale, Y. Khader, E. Khan, G. Khan, Md Nuruzzaman Khan, Y. Khang, Abdullah Khoja, J. Khubchandani, R. Kimokoti, A. Kisa, L. Knibbs, S. Kochhar, S. Kosen, P. Koul, A. Koyanagi, B. Kuate Defo, G. Kumar, D. Lal, Prabhat Lamichhane, C. T. Leshargie, M. Levi, Shanshan Li, Erlyn K Macarayan, M. Majdan, Varshil Mehta, A. Melese, Z. Memish, D. T. Mengistu, T. Meretoja, T. Meštrović, Bartosz Miazgowski, G. Milne, B. Milošević, E. Mirrakhimov, B. Moazen, K. Mohammad, S. Mohammed, L. Monasta, L. Morawska, Seyyed Meysam Mousavi, O. Muhammed, S. Murthy, G. Mustafa, A. Naheed, H. Nguyen, N. B. Nguyen, S. H. Nguyen, T. H. Nguyen, M. I. Nisar, M. Nixon, F. Ogbo, A. Olagunju, T. Olagunju, Eyal Oren, J. Ortiz, M. P A, S. Pakhalé, Shanti Patel, Deepak Paudel, D. Pigott, M. Postma, M. Qorbani, Anwar Rafay, A. Rafiei, V. Rahimi-Movaghar, R. Rai, M. S. Rezai, Nicholas Roberts, L. Ronfani, S. Rubino, Saeed Safari, S. Safiri, Z. Saleem, E. Sambala, A. Samy, M. Šantrić Milićević, B. Sartorius, S. Sarvi, M. Savic, M. Sawhney, S. Saxena, S. Seyedmousavi, M. Shaikh, M. Sharif, A. Sheikh, M. Shigematsu, David L. Smith, R. Somayaji, J. Soriano, C. Sreeramareddy, M. Sufiyan, M. Temsah, B. Tessema, Mebrahtu Teweldemedhin, M. Tortajada-Girbés, B. Tran, Khanh B. Tran, Afewerki Gebremeskel Tsadik, K. Ukwaja, I. Ullah, T. Vasankari, G. Vu, Fiseha Wadilo Wada, Yasir Waheed, T. West, C. Wiysonge, Ebrahim M. Yimer, N. Yonemoto, Z. Zaidi, T. Vos, Stephen S. Lim, C. Murray, A. Mokdad, Simon Iain Hay, R. Reiner +198 moresemanticscholar +1 more source