Results 201 to 210 of about 910,981 (387)
Nonvalue of sputum culture in the management of lower respiratory tract infections [PDF]
Joseph R. Lentino, David A. Lucks
openalex +1 more source
Manganese Neurotoxicity and Familial Disorders of Manganese Transport
ABSTRACT Manganese is the 12th most common element in the Earth's crust and is an essential industrial component. Biologically, this metal plays an important role as a constituent of numerous enzymes. While manganese is required for normal biochemical and physiological processes, manganese excess can lead to significant toxicity, particularly to the ...
Sidney M. Gospe Jr.
wiley +1 more source
Lower respiratory tract infections are a common problem in our society. In recurrent lower respiratory tract infections the cause may be either general impairment of immune mechanism, abnormalities of mucus or abnormalities of cilia.
Ihsan-ullah Mahsud, Shahab ud Din
doaj
Model‐Informed Drug Development Applications and Opportunities in mRNA‐LNP Therapeutics
The utilization of lipid nanoparticles (LNP) for encapsulating mRNA has revolutionized the field of therapeutics, enabling the rapid development of COVID‐19 vaccines and cancer vaccines. However, the clinical development of mRNA‐LNP therapeutics faces numerous challenges due to their complex mechanisms of action and limited clinical experience.
Jiawei Zhou+6 more
wiley +1 more source
J. Gerber+14 more
semanticscholar +1 more source
Respiratory tract infections [PDF]
openaire +1 more source
Polymyxins are used against highly resistant Gram‐negative pathogens, and nephrotoxicity (acute kidney injury, AKI) is the major dose‐limiting adverse effect. We aimed to develop a well‐informed population pharmacokinetic/toxicodynamic (PK/TD) model using the largest polymyxin B‐treated critically ill patient population studied to inform polymyxin B ...
Patrick O. Hanafin+19 more
wiley +1 more source
Probiotics for preventing acute upper respiratory tract infections
Q. Hao, B. Dong, Taixiang Wu
semanticscholar +1 more source