Results 251 to 260 of about 935,849 (402)

Clinically Important Endpoints in Individuals With Leukodystrophy: A Multisite Study

open access: yesAnnals of the Child Neurology Society, EarlyView.
ABSTRACT Importance Leukodystrophies are a diverse group of rare disorders that disrupt central myelination. These disorders present with a broad spectrum of neurological severity and are associated with a range of potential secondary complications, such as scoliosis and failure of independent feeding.
Emma R. Kotes   +31 more
wiley   +1 more source

Microbiological aetiology of paediatric respiratory tract infections in Kyrgyzstan. [PDF]

open access: yesBMC Infect Dis
Osmonbaeva N   +19 more
europepmc   +1 more source

The Release of Leukotrienes in the Respiratory Tract during Infection with Respiratory Syncytial Virus: Role in Obstructive Airway Disease

open access: bronze, 1988
Benjamin Volovitz   +4 more
openalex   +1 more source

Safety, Tolerability, and Pharmacokinetics of the Long‐Acting SARS‐CoV‐2–Neutralizing Monoclonal Antibody Combination AZD7442 (Tixagevimab/Cilgavimab) in Healthy Chinese Adults

open access: yesClinical Pharmacology in Drug Development, EarlyView.
Abstract AZD7442, a combination of extended half‐life monoclonal antibodies tixagevimab and cilgavimab, was shown to neutralize previously circulating SARS‐CoV‐2 variants. This study evaluated safety, tolerability, pharmacokinetics, and pharmacodynamics of AZD7442 in healthy Chinese adults. In this randomized, placebo‐controlled, Phase 1 study, AZD7442
Nanyang Li   +11 more
wiley   +1 more source

Profiles of viral pathogens from individuals with acute respiratory tract infections in northern Tanzania. [PDF]

open access: yesIJID Reg
Mollel JS   +8 more
europepmc   +1 more source

A survey of virus infections of the respiratory tract of cattle and their association with disease

open access: bronze, 1980
E. J. Stott   +7 more
openalex   +1 more source

Model‐Informed Drug Development Applications and Opportunities in mRNA‐LNP Therapeutics

open access: yesClinical Pharmacology &Therapeutics, EarlyView.
The utilization of lipid nanoparticles (LNP) for encapsulating mRNA has revolutionized the field of therapeutics, enabling the rapid development of COVID‐19 vaccines and cancer vaccines. However, the clinical development of mRNA‐LNP therapeutics faces numerous challenges due to their complex mechanisms of action and limited clinical experience.
Jiawei Zhou   +6 more
wiley   +1 more source

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