Rapid and Sensitive Fluorescent RT-RAA Assay for the Detection of a Panel of Six Respiratory Viruses. [PDF]
Guo X +6 more
europepmc +1 more source
Transmission routes of respiratory viruses among humans
Jasmin S Kutter +4 more
semanticscholar +1 more source
SETDB2 epigenetically represses Smad3 transcription by increasing H3K9me3 enrichment at its promoter, thereby mitigating podocyte dysfunction in DKD. The transcription factor TCF21 binds directly to the Setdb2 promoter and enhances its expression in podocytes. Abstract Podocyte dysfunction represents both an early pathological hallmark and a key driver
Lanfang Li +14 more
wiley +1 more source
A CRISPR-assisted passive microfluidic chip for rapid, visual detection of multiple respiratory viruses. [PDF]
Li X, Guo J, Yang H, Wu Y, Xie Z, Li D.
europepmc +1 more source
T-Cell Profiles In Bronchoalveolar Lavage (BAL) Of Wheezing Children With and Without A History Of Respiratory Syncytial Virus (RSV) Lower Respiratory Tract Infection [PDF]
Chang-Kuen Kim +3 more
openalex +1 more source
Alphaviral Capsid Proteins Inhibit Stress Granule Assembly via Competitive RNA Binding With G3BP1
Stress granules exert antiviral functions. This study illustrates a conserved function of alphaviral capsid proteins in modulating stress granules. Oligomerization mediated by a helical motif coupled with a positively charged intrinsically disordered region (IDR) directly competes with G3BP1 for RNA binding, thereby disrupting G3BP1‐RNA liquid–liquid ...
Yun Zhang +10 more
wiley +1 more source
Development of cell combos micromethod to isolate respiratory viruses not detected by molecular techniques. [PDF]
Valade M +5 more
europepmc +1 more source
GPCRs in CAR‐T Cell Immunotherapy: Expanding the Target Landscape and Enhancing Therapeutic Efficacy
Chimeric antigen receptor T cell therapy faces dual challenges of target scarcity and an immunosuppressive microenvironment in solid tumors. This review highlights how G protein‐coupled receptors can serve as both novel targets to expand the therapeutic scope and functional modules to enhance CAR‐T cell efficacy.
Zhuoqun Liu +11 more
wiley +1 more source

