Results 221 to 230 of about 31,452,884 (260)

SMOKING AND PRODUCTIVITY IN THE WORKPLACE. OVERALL REPORT.

, 1984
RESPONSE ANALYSIS
core  

Serum Proteomic Signatures of Rheumatoid Arthritis Risk and Response: Analysis of a Rheumatoid Arthritis Interception Trial. [PDF]

Arthritis Rheumatol
Jasenecova M, Coyle C, Mihalovits A, Ryan S, Pook E, Perucha E, Harker G, Chin M, Norton S, Cope AP.   +9 more
europepmc   +1 more source

Somatostatin receptor 4 (SSTR4) is a tumor suppressor in cutaneous and head & neck squamous cell carcinomas

Molecular Oncology, EarlyView.
This study identifies somatostatin receptor 4 (Sstr4) as a critical tumor suppressor against skin and head/neck cancers (HNSCC, cSCC, and BCC). The loss of Sstr4 removes a check on cell growth, causing hyperactivation of the MAPK‐ERK signaling pathway (↑).
Ali Taqvi, Tuan Khang Huynh, Adway Kadam, Zahra Kardan, Yue Yan, Amina Jamal Laham, Sampath Kumar Loganathan   +6 more
wiley   +1 more source

Genome-wide identification and alkaline stress response analysis of the class III peroxidase (PRX) gene family in Castanea mollissima. [PDF]

BMC Plant Biol
Liu X, Zhang T, Lu G, Li Q, Zhao Y, Wang D, Wang X, Zhang G, Zhang H, Wang X, Yu L.   +10 more
europepmc   +1 more source

Castration‐resistant prostate cancer cells are addicted to the high activity of cyclin‐dependent kinase 2

Molecular Oncology, EarlyView.
We show that emergence of castration‐resistant prostate (CRPC) is associated with significant upregulation of cyclins that positively regulate cyclin‐dependent kinase 2 (CDK2) and concomitant downregulation of CDK4 cyclins. This renders CRPC cells dependent on the high activity of CDK2, and CDK2 inhibitors synergistically sensitize CRPC cells to both ...
Joyeeta Chatterjee, Alessia Marin, Shivani Yalala, Harri M. Itkonen   +3 more
wiley   +1 more source

Comprehensive evaluation and climate response analysis of Ginkgo biloba Linn. wood properties across different regions. [PDF]

BMC Plant Biol
Gao T, Li X, Zhou Y, Shang J, Ma Y, Guo J, Fu F, Wang G.   +7 more
europepmc   +1 more source

Partial FAK suppression promotes tumor growth, an effect reversed by macrophage p110δ PI3K inactivation

Molecular Oncology, EarlyView.
Partial inhibition of focal adhesion kinase (FAK) can paradoxically promote tumor growth, rather than simply producing a weaker antitumor effect than that observed with strong FAK suppression. In breast cancer and melanoma models, targeting p110δ PI3K, particularly in macrophages, counteracted these tumor‐promoting effects, highlighting the importance ...
Lydia Xenou, Niki Tzenaki, Anna Tsapara, Maria Tzardi, Evangelia A. Papakonstanti   +4 more
wiley   +1 more source

APPENDIX D: QUESTIONNAIRE.

, 1988
RESPONSE ANALYSIS
core  

Population pharmacokinetics and exposure-response analysis of levofloxacin in Chinese pediatric patients with severe refractory <i>Mycoplasma pneumoniae</i> pneumonia. [PDF]

Antimicrob Agents Chemother
Tao X, Zhou Y, Xu S, Su Y, Tang Y, Zhang S, Chang Z, Xie F, Lv M.   +8 more
europepmc   +1 more source