Results 81 to 90 of about 711,454 (295)
, 2019 Modern seismic design provisions allow structural systems to be designed for reduced forces, which are typically much smaller than the corresponding elastic design loads. This reduction in seismic loads is done by using response modification coefficient.
Erkmen, Bülent, Bulent Erkmen
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Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?
FEBS Letters, EarlyView.This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes +3 more
wiley +1 more source
Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation
FEBS Letters, EarlyView.Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe +3 more
wiley +1 more source
Electronic Journal of Structural Engineering, 2014 In equivalent static analysis procedure, the design seismic force is affected by the response factor related to the inelastic behavior of the structure.
S. B. Talaeitaba +2 more
doaj +1 more source
Difference limen for the Q-factor of room modes
, 2003 A subjective test study was carried out in order to identify the perceptibility of changes in the Q-factor of room modes. The experimental technique concentrates on the identification of difference limen for three levels of Q-factor referring to modes in
Fazenda, Bruno +2 more
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FEBS Letters, EarlyView.This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva +5 more
wiley +1 more source
Archives of Civil Engineering, 2013 Detailed investigation of the effect of the number of end-panel studs on the seismic properties of light-steel shear-panel braces in cold-formed steel frames and in particular the associated response modification coefficients (R) factor, are presented in
Tafti Mohammad Reza Javaheri +1 more
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Role of SUMO-1 modification in transcriptional activation
, 2012 In unstimulated cells, the transcription factor NF-κB is held in the cytoplasm in an inactive state by IκB inhibitor proteins. Activation of NF--KB is mediated by signal induced degradation of IκBα via the ubiquitin proteasome-dependent pathway ...
Pinto Desterro, Maria Joana
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, 2017 The response modification factor is one of the seismic design parameters that determine the nonlinear performance of building structures during strong earthquakes. Most seismic design codes lead to reduced loads.
Abdi, Heshmatollah +8 more
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Glucocorticoid receptor activation by long acting steroids and its modification by inflammation [PDF]
, 2007 s: Glucocorticoids have an effective anti-inflammatory, anti-proliferative and immunomodulatory activity. Therefore this class of drugs is used worldwide for the treatment of inflammatory diseases and to prevent rejection following organ transplantation.
Yang, Jing-Qing
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