Results 31 to 40 of about 8,736,512 (307)

Immune Microenvironment and Response in Prostate Cancer Using Large Population Cohorts

Frontiers in Immunology, 2021
Immune microenvironment of prostate cancer (PCa) is implicated in disease progression. However, previous studies have not fully explored PCa immune microenvironment.
Xiaohan Ren, Xiaohan Ren, Xinglin Chen, Xinglin Chen, Xu Zhang, Xu Zhang, Silin Jiang, Silin Jiang, Tongtong Zhang, Tongtong Zhang, Guangyao Li, Guangyao Li, Zhongwen Lu, Zhongwen Lu, Dong Zhang, Dong Zhang, Shangqian Wang, Shangqian Wang, Chao Qin, Chao Qin   +19 more
doaj   +1 more source

Rapid Response to Trametinib Combined With Chemotherapy for Infant BRAF‐Fused Chiasmatic Glioma

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Infants, less than 1 year, with chiasmatic gliomas (ICG) present a major therapeutic challenge due to large tumor size, decreased vision, rapid progression, and poor response to vincristine/carboplatin chemotherapy. The majority have a BRAF fusion, which may respond to downstream MEK inhibitors but response time is slow. There are no safety or
Helen Toledano, Alexander Yelak, Walid Kaadan, Shlomo Caduri, Rivka Friedland, Orli Michaeli, Gad Dotan, Osnat Konen   +7 more
wiley   +1 more source

Response rate of patients with baseline brain metastases from recently diagnosed non‐small cell lung cancer receiving radiotherapy according to EGFR, ALK and KRAS mutation status

Thoracic Cancer, 2020
Background Previous studies have identified that patients with EGFR mutations tend to have better responses to targeted therapy, as well as chemotherapy; however, the effect of genetic alterations in terms of radiotherapy (RT)‐related outcomes has not ...
Oscar Arrieta, Laura‐Alejandra Ramírez‐Tirado, Enrique Caballé‐Perez, Alberto Mejia‐Perez, Zyanya Lucia Zatarain‐Barrón, Andrés F. Cardona, Francisco Lozano‐Ruíz, Manuel Segura‐González, Graciela Cruz‐Rico, Federico Maldonado, Rafael Rosell   +10 more
doaj   +1 more source

Effectiveness of immunosuppressant use for the treatment of immune checkpoint inhibitor-induced liver injury: A systematic review and meta-analysis

Frontiers in Oncology, 2023
BackgroundImmune-mediated liver injury caused by checkpoint inhibitors (ILICI) is a challenging clinical management issue. Although immunosuppressants are widely used to manage ILICI, no large-scale studies have proved definitive evidence for the most ...
Kefan Chen, Kefan Chen, Junhao He, Junhao He, Jing Xu, Jie Chen   +5 more
doaj   +1 more source

Cognitive Functioning in Vorinostat‐Treated Pediatric and Young Adult Patients Over the First 180 Days After Hematopoietic Stem Cell Transplant

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Purpose Cognitive and psychological difficulties could negatively interfere with treatment adherence and quality of life before and after hematopoietic stem cell transplant (HSCT). Methods to mitigate these changes may have positive effects on treatment success.
Kristen L. Votruba, Michelle Rozwadowski, Thomas Braun, April Rahrig, Edward Peres, Kirsten M. Williams, Vanessa Fabrizio, Julie‐An Talano, Carrie L. Kitko, Nicolas Parnell, Pavan Reddy, Sung Won Choi   +11 more
wiley   +1 more source

Establishment of a cohort for deep phenotyping of the immune response to influenza vaccination among elderly individuals recruited from the general population

Human Vaccines & Immunotherapeutics, 2017
Elderly individuals have the highest burden of disease from influenza infection but also the lowest immune response to influenza vaccination. A better understanding of the host response to influenza vaccination in the elderly is therefore urgently needed.
Manas K. Akmatov, Peggy Riese, Marcus May, Leonhard Jentsch, Malik W. Ahmed, Damaris Werner, Anja Rösel, Megan Tyler, Kevin Pessler, Jana Prokein, Inga Bernemann, Norman Klopp, Blair Prochnow, Stephanie Trittel, Aravind Tallam, Thomas Illig, Christoph Schindler, Carlos A. Guzmán, Frank Pessler   +18 more
doaj   +1 more source

Immune Response to Hepatitis B Virus Vaccine Among People Living With HIV: A Meta-Analysis

Frontiers in Immunology, 2021
BackgroundThere is conflicting evidence about whether a double dose of the hepatitis B virus (HBV) vaccine induces better immunity than the standard-dose vaccine for people living with HIV (PLWH).
Yakun Tian, Wei Hua, Yaxin Wu, Tong Zhang, Wen Wang, Hao Wu, Caiping Guo, Xiaojie Huang   +7 more
doaj   +1 more source

The transient response of global-mean precipitation to increasing carbon dioxide levels [PDF]

, 2010
The transient response of global-mean precipitation to an increase in atmospheric carbon dioxide levels of 1% yr(-1) is investigated in 13 fully coupled atmosphere-ocean general circulation models (AOGCMs) and compared to a period of stabilization ...
Bala G, Meehl G A, Mitchell J F B, Piers M Forster, Timothy Andrews, Wild M   +5 more
core   +1 more source

A PRSZT Registry Analysis of Prognostic Factors Influencing Survival and Relapse Rates After Second Allogeneic Hematopoietic Stem Cell Transplantation in Pediatric Acute Lymphoblastic Leukemia

Pediatric Blood &Cancer, EarlyView.
ABSTRACT A second allogeneic (allo‐)hematopoietic stem cell transplantation (HSCT2) is a potential curative option for pediatric patients with acute lymphoblastic leukemia (ALL) following relapse after first allogeneic transplantation (HSCT1), but its efficacy is limited by high relapse rates and transplant‐related toxicity in highly pretreated ...
Ava Momm, Imme Haubitz, Rita Beier, Martin Zimmermann, Andrej Lissat, Peter Bader, Matthias Eyrich, Jan‐Henning Klusmann, Matthias Wölfl, Paul‐Gerhardt Schlegel, Verena Wiegering   +10 more
wiley   +1 more source

Surveys from inside: An assessment of unit nonresponse bias with internal criteria

Survey Research Methods, 2007
The article uses the so called “internal criteria of representativeness” to assess the unit nonresponse bias in five European comparative survey projects.
Ulrich Kohler
doaj   +1 more source