Results 151 to 160 of about 1,615,018 (245)
Topical propranolol for infantile hemangioma: a comprehensive review of mechanisms, clinical efficacy, and novel formulations. [PDF]
Front PediatrChen F +10 more
europepmc +1 more source
Intein‐based modular chimeric antigen receptor platform for specific CD19/CD20 co‐targeting
Molecular Oncology, EarlyView.CARtein is a modular CAR platform that uses split inteins to splice antigen‐recognition modules onto a universal signaling backbone, enabling precise, scarless assembly without re‐engineering signaling domains. Deployed here against CD19 and CD20 in B‐cell malignancies, the design supports flexible multi‐antigen targeting to boost T‐cell activation and
Pablo Gonzalez‐Garcia +9 more
wiley +1 more source
A STUDY ON RESPONSE REDUCTION FACTOR OF RC WATER TANK
International Journal of Advance Engineering and Research Development, 2015 openaire +1 more source
Molecular Oncology, EarlyView.Clinical trials on PARP inhibitors in urothelial carcinoma (UC) showed limited efficacy and a lack of predictive biomarkers. We propose SLFN5, SLFN11, and OAS1 as UC‐specific response predictors. We suggest Talazoparib as the better PARP inhibitor for UC than Olaparib.
Jutta Schmitz +15 more
wiley +1 more source
Exploring microbial signatures in sarcoidosis: etiological and therapeutic implications of host-microbiota interactions. [PDF]
Front ImmunolRizzi L, Larizza G, Suppressa P.
europepmc +1 more source
Molecular Oncology, EarlyView.HDAC4 is degraded by the E3 ligase FBXW7. In colorectal cancer, FBXW7 mutations prevent HDAC4 degradation, leading to oxaliplatin resistance. Forced degradation of HDAC4 using a PROTAC compound restores drug sensitivity by resetting the super‐enhancer landscape, reprogramming the epigenetic state of FBXW7‐mutated cells to resemble oxaliplatin ...
Vanessa Tolotto +13 more
wiley +1 more source
Precision Medicine in Asthma: The Role of Biomarkers. [PDF]
Immunotargets TherQuek E, Horn N, Siddiqui S.
europepmc +1 more source
ASSESSMENT OF RESPONSE REDUCTION FACTOR FOR ASYMMETRIC RC FRAME BUILDING
International Journal of Advance Engineering and Research Development, 2015 openaire +1 more source
Molecular Oncology, EarlyView.Development of therapies targeting cancer‐associated fibroblasts (CAFs) necessitates preclinical model systems that faithfully represent CAF–tumor biology. We established an in vitro coculture system of patient‐derived pancreatic CAFs and tumor cell lines and demonstrated its recapitulation of primary CAF–tumor biology with single‐cell transcriptomics ...
Elysia Saputra +10 more
wiley +1 more source
Study on the effects of zirconia restorations in oral prosthodontics on inflammatory factor levels and masticatory function. [PDF]
Medicine (Baltimore)Zhang W, Zou F, Xiong J.
europepmc +1 more source