Results 111 to 120 of about 12,069,491 (256)

Functional profiling of STXBP1 missense variants using a novel dual‐readout fluorometric assay

Epilepsia, EarlyView.
Abstract Objective STXBP1‐related disorders (STXBP1‐RD) are among the most common genetic neurodevelopmental disorders, marked by early onset epilepsy, global developmental delay, and motor impairments. Many missense variants remain uncharacterized, limiting accurate variant interpretation and hindering development of precision therapies.
Elisa A. Waxman, Jennine M. Dawicki‐McKenna, Ian McSalley, Anna J. Prentice, Torrey A. Chisari, Sarah M. Ruggiero, Jillian L. McKee, Alex J. Felix, Giulia Pavani, Benjamin L. Prosser, Michael J. Boland, Ingo Helbig   +11 more
wiley   +1 more source

Genetic Algorithm‐Driven Analysis of Gravitational Water Vortex Power Plant Runner Performance: A Comparative Study Integrating Experimental and Computational Fluid Dynamics

Energy Science &Engineering, EarlyView.
This study integrates genetic algorithm optimization, CFD simulation, and experimental validation to identify the optimal runner geometry for a gravitational water vortex turbine. The combined approach enhances vortex stability and improves energy conversion efficiency, demonstrating strong agreement between predicted and measured performance ...
Zakaria. A. Mwakitwange, Adam Faraji
wiley   +1 more source

Study on the removal of high contents of ammonium from piggery wastewater by clinoptilolite and the corresponding mechanisms

Open Chemistry, 2019
In this study, a clinoptilolite was applied to remove ammonium from piggery wastewater. The performance of ammonium removal and the correspondingly mechanisms were discussed.
Nan Liu, Yingying Li, Jixiang Li, Dujuan Ouyang, Wenjuan Wang   +4 more
doaj   +1 more source

Optimization of ultrasound-assisted extraction of glycyrrhizic acid from licorice using response surface methodology

Integrative Medicine Research, 2017
Background: The present study optimized ultrasound-assisted extraction conditions to maximize extraction yields of glycyrrhizic acid from licorice. Methods: The optimal extraction temperature (X1), extraction time (X2), and methanol concentration (X3 ...
Seol Jang, A. Yeong Lee, A. Reum Lee, Goya Choi, Ho Kyoung Kim   +4 more
doaj   +1 more source

THE EFFECT OF MACHINING PARAMETERS ON SURFACE ROUGHNESS USING RESPONSE SURFACE METHODOLOGY (RSM)

The effect of machining parameters on surface roughness using response surface methodology (RSM) was investigated. The data used for the work was obtained from the previous work titled ‘’effect of machining parameters on the surface roughness of medium carbon steel using lathe machine’’.
Ihom, A.P., Odeh, Emmanuel Udama, Ayanam, Bassey Sam   +2 more
openaire   +2 more sources

Experimental Investigation and ANN‐Based Prediction of CI Engine Performance Fueled With Waste Plastic Oil–Diesel Blends Containing Al2O3 Nanoparticles

Energy Science &Engineering, EarlyView.
Waste plastic oil–diesel blends enhanced with Al2O3 nanoparticles were experimentally evaluated in a compression ignition engine under varying injection timings and modeled using artificial neural networks (ANNs). The optimized WP20PD + 1000 ppm blend improved brake thermal efficiency and reduced fuel consumption, while ANN prediction achieved high ...
Dudekula Jamal Basha, Upendra Rajak, Abhishek Agarwal, Balram Yelamasetti, Manoj Panchal, Sudheer Kumar, Abhishek Dasore   +6 more
wiley   +1 more source

RSM–ANFIS‐Based Process Optimization of Thermo‐Sonication of Amla Juice: Effect on Enzyme Inactivation, Physico‐Chemical, Phytochemical, Sensory, and Microbiological Quality

Food Chemistry International, EarlyView.
Thermo‐sonication parameters were optimized to maximize PPO inactivation while maintaining overall juice quality. ANFIS demonstrated superior predictive accuracy with higher R2 and lower RMSE compared to RSM. Further, the quality assessment of treated juice highlighted the potential of thermo‐sonication as a sustainable alternative to conventional ...
Sumaiya Fatima, Vivek Kumar
wiley   +1 more source

Profiling of Dietary Fiber From Pumpkin (Cucurbita moschata) Seed Hulls Pertaining to Monosaccharide Composition, Structural, Thermal, and Functional Properties

Food Chemistry International, EarlyView.
Dietary fiber (soluble/insoluble) was recovered from pumpkin seed hulls using hydrothermal extraction. Process parameters were optimized, and a comprehensive profiling of recovered fiber fractions was performed. ABSTRACT Insoluble (IDF) and soluble dietary fiber (SDF) were recovered from pumpkin seed hulls (PSHs) using hydrothermal treatment ...
Rishabh Thakur, H. K. Sharma
wiley   +1 more source

Effect of process parameters on the rheological properties of banana (Musa acuminata) fiber and optimization using response surface methodology

Journal of Agriculture and Food Research
The labor-intensive, time-consuming, and uneconomical nature of manually extracting banana (Musa acuminata) fibers from pseudo-stem sheaths has prompted the exploration of automation as a solution.
Shubham Pandey, R.K. Naik, Vinay Kumar Pandey, Shivangi Srivastava, Gulden Goksen, Shivam Pandey, Sarvesh Rustagi   +6 more
doaj   +1 more source

Optimization of pectinase extraction from mango (Mangifera indica cv. Chokanan) peel using response surface methodology [PDF]

, 2013
Today pectinases (EC 3.2.1.15) have become an integral part of the food and feed industry and plant peel could be a potential source of pectinase. Thus, the main objective of the study was the optimization of pectinase extraction from mango (Mangifera ...
Abd. Manap, Mohd. Yazid, Mehrnoush, Amid
core   +1 more source