Results 241 to 250 of about 23,753,211 (302)

Predictive and prognostic biomarkers of Bacillus Calmette‐Guérin therapy failure in bladder cancer patients: A systematic review

open access: yesMolecular Oncology, EarlyView.
High‐risk bladder cancer is typically treated with Bacillus Calmette‐Guérin (BCG), but 30–40% of patients relapse. No FDA‐ or CE‐approved biomarkers currently predict or prognosticate BCG failure. We systematically reviewed the literature and identified 72 eligible studies, revealing several promising biomarkers associated with BCG treatment response ...
Rui Ribeiro‐Pereira   +7 more
wiley   +1 more source

Using memory recall response time on digital cognitive testing to detect subtle cognitive changes among cognitively unimpaired older adults. [PDF]

open access: yesAlzheimers Dement
Kim H   +11 more
europepmc   +1 more source

NAPRT loss promotes lung tumor initiation and growth through AKT signaling independently of NAD+ biosynthesis

open access: yesMolecular Oncology, EarlyView.
Loss of NAPRT promotes lung tumor initiation and growth through a noncanonical mechanism, independent of its role in NAD+ biosynthesis. Mechanistically, NAPRT depletion activates the mTORC2‐driven AKT/β‐catenin signaling axis to enhance clonogenic and invasive phenotypes. Furthermore, lung‐specific Naprt deletion significantly increases tumor burden in
Myung Joon Oh   +11 more
wiley   +1 more source

Urban traffic accidents in Isfahan city: a study of prehospital response time intervals. [PDF]

open access: yesInt J Emerg Med
Nasr Isfahani M   +4 more
europepmc   +1 more source

Linking the neural signature of response time variability to Alzheimer's disease pathology and cognitive functioning. [PDF]

open access: yesNetw Neurosci
Teng J   +4 more
europepmc   +1 more source

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