Results 41 to 50 of about 251,497 (215)
By dawn or dusk—how circadian timing rewrites bacterial infection outcomes
FEBS Letters, EarlyView.The circadian clock shapes immune function, yet its influence on infection outcomes is only beginning to be understood. This review highlights how circadian timing alters host responses to the bacterial pathogens Salmonella enterica, Listeria monocytogenes, and Streptococcus pneumoniae revealing that the effectiveness of immune defense depends not only
Devons Mo +2 more
wiley +1 more source
Medical Science Liaisons (MSL) in Africa: a perspective
The Pan African Medical Journal, 2019 The role of a Medical Science Liaison (MSL) is of growing importance to pharmaceutical, biotechnology, diagnostic and medical device companies. Through scientific engagement MSLs add value to clinical practice, ultimately benefiting patients.
Dwayne +5 more
doaj +1 more source
Geneza i historia urzędu dziekana
Studia Koszalińsko-Kołobrzeskie, 2020 The Dean’s Office takes its beginning in the Apostolic era, where the Apostles’ assistants were deacons. Through a choreopioscope, Archdeacon and Archpriest, the predecessor of the present Dean, the office changed its character from charitable to charity
Piotr Łowicki
doaj +1 more source
Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?
FEBS Letters, EarlyView.This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes +3 more
wiley +1 more source
Molecular bases of circadian magnesium rhythms across eukaryotes
FEBS Letters, EarlyView.Circadian rhythms in intracellular [Mg2+] exist across eukaryotic kingdoms. Central roles for Mg2+ in metabolism suggest that Mg2+ rhythms could regulate daily cellular energy and metabolism. In this Perspective paper, we propose that ancestral prokaryotic transport proteins could be responsible for mediating Mg2+ rhythms and posit a feedback model ...
Helen K. Feord, Gerben van Ooijen
wiley +1 more source
The Roles and Responsibilities of School Social Workers in the African Context: A Scoping Review [PDF]
E-Journal of Humanities, Arts and Social SciencesThe profession of school social work has been acknowledged as being of critical importance on a global scale. However, little is known about the practice of school social work in the African context, specifically the roles and responsibilities of ...
Gift Khumalo +2 more
doaj +1 more source
The Hematopoietic Cell Transplant Pharmacist: A Call to Action
Pharmacy, 2020 Recently, the required training and credentials for as well as the various roles of the hematopoietic cell transplant (HCT) pharmacist have been endorsed by the leading organizations in cellular therapy, the American Society of Transplant and Cellular ...
Amber Clemmons
doaj +1 more source
Crosstalk between the ribosome quality control‐associated E3 ubiquitin ligases LTN1 and RNF10
FEBS Letters, EarlyView.Loss of the E3 ligase LTN1, the ubiquitin‐like modifier UFM1, or the deubiquitinating enzyme UFSP2 disrupts endoplasmic reticulum–ribosome quality control (ER‐RQC), a pathway that removes stalled ribosomes and faulty proteins. This disruption may trigger a compensatory response to ER‐RQC defects, including increased expression of the E3 ligase RNF10 ...
Yuxi Huang +8 more
wiley +1 more source
THE PUBLIC DEFENDER OFFICE IN THE NEW CIVIL PROCEDURE CODE
Revista Eletrônica de Direito Processual, 2015 It is objective and descriptive study about the main forecasts of the New Code of Civil Procedure on the Public Defender Office, as well as their influences and consequences in the work of the Public Defender in the civil lawsuit.
Renan Barros dos Reis
doaj +1 more source