Results 51 to 60 of about 251,497 (215)
This perspective highlights emerging insights into how the circadian transcription factor CLOCK:BMAL1 regulates chromatin architecture, cooperates with other transcription factors, and coordinates enhancer dynamics. We propose an updated framework for how circadian transcription factors operate within dynamic and multifactorial chromatin landscapes ...
Xinyu Y. Nie, Jerome S. Menet
wiley +1 more source
The influence of Islamic mysticism on Iranian education [PDF]
Mysticism can have many effects on our Iranian cultural and spiritual life. This influence can play a significant role in the future of youth education. In this article, we say that mysticism is a kind of individual or personal approach, but education is
Mahmoud Navali
doaj
Labor skillsfor the hardware and construction materials sector in Ocotlán de Morelos, Oaxaca
The objective of this research was to analyze the recruitment and selection process in companies of hardware and construction materials sector, located in the municipality of Ocotlán de Morelos, Oaxaca.
Guadalupe González Pérez +2 more
doaj +1 more source
Disordered but rhythmic—the role of intrinsic protein disorder in eukaryotic circadian timing
Unstructured domains known as intrinsically disordered regions (IDRs) are present in nearly every part of the eukaryotic core circadian oscillator. IDRs enable many diverse inter‐ and intramolecular interactions that support clock function. IDR conformations are highly tunable by post‐translational modifications and environmental conditions, which ...
Emery T. Usher, Jacqueline F. Pelham
wiley +1 more source
Some Aspects of Fight Against Smuggling: Theory and Practice
The article deals with the concept of contraband, it will touch upon the historical aspect and peculiarities of this institute on railway transport. Dependence of smuggling on the level of the state economic development and ways to combat smuggling is ...
Oleg I. Evtushenko
doaj
Background Improvement of knowledge regarding the rights and responsibilities of patients with tuberculosis (TB) (patient charter) through sensitization meeting may have a positive effect on their life and yield better treatment outcomes.
Janmejaya Samal +3 more
doaj +1 more source
Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe +3 more
wiley +1 more source
Multiple ETS family transcription factors bind mutant p53 via distinct interaction regions
Mutant p53 gain‐of‐function is thought to be mediated by interaction with other transcription factors. We identify multiple ETS transcription factors that can bind mutant p53 and found that this interaction can be promoted by a PXXPP motif. ETS proteins that strongly bound mutant p53 were upregulated in ovarian cancer compared to ETS proteins that ...
Stephanie A. Metcalf +6 more
wiley +1 more source

