Results 61 to 70 of about 251,497 (215)

LandXML Encoding of Mixed 2D and 3D Survey Plans with Multi-Level Topology

ISPRS International Journal of Geo-Information, 2017
Cadastral spatial units around the world range from simple 2D parcels to complex 3D collections of spaces, defined at levels of sophistication from textural descriptions to complete, rigorous mathematical descriptions based on measurements and ...
Rodney James Thompson, Peter van Oosterom, Kean Huat Soon   +2 more
doaj   +1 more source

Conserved structural motifs in PAS, LOV, and CRY proteins regulate circadian rhythms and are therapeutic targets

FEBS Letters, EarlyView.
Cryptochrome and PAS/LOV proteins play intricate roles in circadian clocks where they act as both sensors and mediators of protein–protein interactions. Their ubiquitous presence in signaling networks has positioned them as targets for small‐molecule therapeutics. This review provides a structural introduction to these protein families.
Eric D. Brinckman, Anna E. Lester, Brian D. Zoltowski   +2 more
wiley   +1 more source

Roles, Responsibilities, and Functions of Village Health, Sanitation, and Nutrition Committees in India: A Qualitative Evidence Synthesis

Indian Journal of Public Health
National Health Mission instituted the Village Health, Sanitation, and Nutrition Committees (VHSNCs) in 2005, with an aim of ensuring health and well-being for local communities in India.
Sathish Rajaa, Senthilkumar Ramalingam, Maulik Chokashi, Tushar Mokashi   +3 more
doaj   +1 more source

An upstream open reading frame regulates expression of the mitochondrial protein Slm35 and mitophagy flux

FEBS Letters, EarlyView.
This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva, Ariann E. Mendoza‐Martínez, P. Abril Medina‐Flores, Carlos Campero‐Basaldua, Alexander DeLuna, Soledad Funes   +5 more
wiley   +1 more source

Human Duties and Rights in an Intercultural Perspective

Age of Human Rights Journal, 2022
This paper reflects on the possibility of opening new ways of revaluing the role of human responsibilities and duties by establishing a relationship with rights that goes further than a simple correspondence between correlative terms.
Emilia Bea
doaj  

Les institutions et les acteurs en santé au travail au Québec et en France : regard croisé

Perspectives Interdisciplinaires sur le Travail et la Santé, 2010
In Québec, as in France, the institutional environment in the occupational health and safety field is extremely important. The Québec law of December 21, 1979, orchestrating its entire organization, placed the Commission de la santé et de la sécurité du ...
Nathalie Ferre
doaj   +1 more source

PICALM::MLLT10 translocated leukemia

FEBS Letters, EarlyView.
This comprehensive review of PICALM::MLLT10 translocated acute leukemia provides an in‐depth review of the structure and function of CALM, AF10, and the fusion oncoprotein (1). The multifaceted molecular mechanisms of oncogenesis, including nucleocytoplasmic shuttling (2), epigenetic modifications (3), and disruption of endocytosis (4), are then ...
John M. Cullen, Antonia C. Nakatsugawa, Natalie Barton, Henry Haines, Gary S. Stein, Janet L. Stein, Daniel S. Wechsler, Jessica L. Heath   +7 more
wiley   +1 more source

Pharmacy Technicians’ Roles and Responsibilities in the Community Pharmacy Sector: A Welsh Perspective

Pharmacy, 2020
Background: Healthcare delivery models in Wales are changing in response to unprecedented pressure on the National Health Service UK (NHS). Community pharmacies will be prioritised to address public health and clinical needs at a local level.
Rebecca Chamberlain, Jan Huyton, Delyth James   +2 more
doaj   +1 more source

Inhibiting stearoyl‐CoA desaturase suppresses bone metastatic prostate cancer by modulating cellular stress, mTOR signaling, and DNA damage response

FEBS Letters, EarlyView.
Bone metastasis in prostate cancer (PCa) patients is a clinical hurdle due to the poor understanding of the supportive bone microenvironment. Here, we identify stearoyl‐CoA desaturase (SCD) as a tumor‐promoting enzyme and potential therapeutic target in bone metastatic PCa.
Alexis Wilson, Mackenzie K Herroon, Shane Mecca, Laimar C Garmo, Jacob Lindquist, Shrila Rajendran, Steve M. Patrick, Izabela Podgorski   +7 more
wiley   +1 more source

Teacher educators' challenges: focusing on teacher training colleges in Laos

Frontiers in Education
Understanding challenges faced by teacher educators further contributes to improvement suggestions on their professional development. It is a pressing study on their working in developing countries where teacher education has experienced reforms to ...
Khampheng Sengsoulintha
doaj   +1 more source