Results 61 to 70 of about 1,451,435 (348)
FEBS Letters, EarlyView.Bone metastasis in prostate cancer (PCa) patients is a clinical hurdle due to the poor understanding of the supportive bone microenvironment. Here, we identify stearoyl‐CoA desaturase (SCD) as a tumor‐promoting enzyme and potential therapeutic target in bone metastatic PCa.
Alexis Wilson +7 more
wiley +1 more source
Structural biology of ferritin nanocages
FEBS Letters, EarlyView.Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley +1 more source
The responsibility to protect and the great powers: the tensions of dual responsibility [PDF]
, 2015 Since the UN’s 2005 adoption of the Responsibility to Protect (R2P) the five permanent members (P5) of the organisation’s Security Council have been burdened with a special dual responsibility, entailing a special responsibility to maintain international
Morris, Justin
core +1 more source
Molecular Oncology, EarlyView.Detection of extrachromosomal circular DNA (eccDNA) in plasma samples from EGFR‐mutated non‐small cell lung cancer patients. Plasma was collected before and during treatment with the EGFR‐tyrosine kinase inhibitor osimertinib. Plasma eccDNA was detected in all cancer samples, and the presence of the EGFR gene on eccDNA serves as a potential biomarker ...
Simone Stensgaard +5 more
wiley +1 more source
Politeja, 2018 The article presents the evolution of the approach to humanitarian intervention that in the 21st century had been framed in the concept of Responsibility to Protect.
Jakub Kościółek
doaj +1 more source
Bringing human rights home: refugees, reparation, and the responsibility to protect [PDF]
, 2015 Human rights, it is often observed, have become a common global language for making moral claims. One consequence of this is that there is a huge range of ways in which states, organisations and other actors draw on, invoke and mobilise human rights in ...
Souter, James
core +1 more source
Molecular Oncology, EarlyView.Liquid biopsy enables minimally invasive, real‐time molecular profiling through analysis of circulating biomarkers in biological fluids. This Perspective highlights the importance of training pathologists through integrative educational programs, such as the European Masters in Molecular Pathology, to ensure effective and equitable implementation of ...
Marius Ilié +13 more
wiley +1 more source
Past, present and future of the «Responsibility to protect»: a bumpy journey [PDF]
Janus.net, 2017 The aim of this article is to study the “Responsibility to Protect”, its evolution since 2000 and what can be expected for its future. Concurrently, the paper takes into account the need to protect populations, victims of certain types of aggression and ...
Vítor Manuel Ramon Fernandes
doaj
ASEAN’s Response to the Myanmar Military Coup: From Non-Intervention to Responsibility to Protect
Revista UNISCI, 2022 This article examines how ASEAN has reacted to the military coup in Myanmar. The February 1, 2021 coup was appalling because Myanmar was progressing toward democracy especially since Suu Kyi’s National League for Democracy (NLD) won a landslide victory ...
Ali Muhammad, Ahmad Sahide
doaj
The legitimation and criticism of violence in international law. A po¬litical science perspective [PDF]
Кантовский сборник, 2013 This article considers the practice of justification of arbitrary use of force, which poses a paradox and was not foreseen in Kant’s peace project. It is paradoxical because modern international law — unlike classical law — is aimed not at regulating ...
Brock L.
doaj +1 more source