Humanitarian law, refugee protection and the Responsibility to Protect
, 2020 The development since 2001 of the doctrine of the Responsibility to Protect (R2P) has been one of the most important normative developments in international relations in the last century.
Maley, William
core +1 more source
Emerging experimental and computational methods for studying redox‐regulated structural transitions
FEBS Letters, EarlyView.Redox reactions can reshape proteins and alter how they behave in cells, with important consequences for health and disease. This review explores emerging experimental and computational approaches for discovering these redox‐sensitive protein switches, revealing their structural effects, and predicting their behavior, opening new opportunities to ...
Tasneem Rass +2 more
wiley +1 more source
Unravelling the paradox of the 'responsibility to protect'
, 2009 This paper explains that the desire to evade Western responsibility is at the heart of the paradox of ‘the responsibility to protect’ (R2P) doctrine, and that this desire for evasion enables us to understand the gap between the rhetorical promise of ...
Chandler, D.C.
core +1 more source
The legitimation and criticism of violence in international law. A po¬litical science perspective [PDF]
Кантовский сборник, 2013 This article considers the practice of justification of arbitrary use of force, which poses a paradox and was not foreseen in Kant’s peace project. It is paradoxical because modern international law — unlike classical law — is aimed not at regulating ...
Brock L.
doaj +1 more source
Responsibility While Protecting: Implementation and the Future of Responsibility to Protect
, 2015 Ten years after the Responsibility to Protect (RtoP) was unanimously adopted by the General Assembly in 2005, the international community is still faced with challenges of ensuring that genocide, crimes against humanity, war crimes, and ethnic cleansing are never again committed.
Powers, Margaret M. +4 more
openaire +2 more sources
Structural and biochemical analysis of a B12 superbinder
FEBS Letters, EarlyView.BtuG proteins are vitamin B12 scavengers in Bacteroides thetaiotaomicron, a dominant human gut bacterium. We present crystal structures of three BtuG homologs bound to cobalamin and its precursor cobinamide, revealing picomolar binding affinities, among the highest known for any natural protein.
Jose M. Martinez Felices +3 more
wiley +1 more source
Reviewing the Responsibility to Protect: Origins, Implementation and Controversies
, 2019 This volume is a collection of some of the key essays by Ramesh Thakur on the origins, implementation and future prospects of the Responsibility to Protect (R2P) norm.
Thakur, Ramesh
core +1 more source
The Shewanella oneidensis Fic enzyme SoFic targets the switch‐I region of EF‐Tu for AMPylation
FEBS Letters, EarlyView.Fic enzymes mediate diverse post‐translational modifications across all domains of life, including AMPylation. Prokaryotic EF‐Tu can be AMPylated and deAMPylated by the conserved Fic enzyme SoFic. Structural and biochemical approaches were used to characterize the effect of AMPylation on EF‐Tu, SoFic's enzymatic activities, and the enzyme‐target ...
Svenja Runge +6 more
wiley +1 more source
The Responsibility to Protect: A Forward-looking Agenda
, 2020 One of the most dramatic normative developments of our time relates to the use of military force to protect human beings by finessing the tension between state sovereignty and international intervention through a redefinition of sovereignty and ...
Thakur, Ramesh
core +1 more source
Protection Norms and Human Rights: A Rights-Based Analysis of the Responsibility to Protect and the Protection of Civilians in Armed Conflict [PDF]
, 2012 In the international context, human rights are rarely secured by the black letter of law, but rather by the soft laws, political policies and moral prescriptions of protection norms .
Breakey, Hugh
core +1 more source