Results 141 to 150 of about 1,402,994 (298)

Response to Allopurinol and Febuxostat According to the Fractional Excretion of Urate in Men With Gout

open access: yesArthritis Care &Research, EarlyView.
Objective Body mass index (BMI), glomerular filtration rate (GFR), and pretreatment urate levels have been reported to influence the urate‐lowering response to allopurinol. We investigated whether the fractional excretion of uric acid (FEUA) also modulates this response and relates to oxypurinol concentrations.
Pascal Richette   +13 more
wiley   +1 more source

Navigating the complexities of AI and digital governance: the 5W1H framework

open access: yesJournal of Responsible Technology
As AI and digital technologies advance rapidly, governance frameworks struggle to keep pace with emerging applications and risks. This paper introduces a ''5W1H'' framework to systematically analyze AI governance proposals through six key questions: What
S. Matthew Liao   +3 more
doaj   +1 more source

Combining development, capacity building and responsible innovation in GCRF-funded medical technology research. [PDF]

open access: yesDev World Bioeth, 2022
Bezuidenhout L   +5 more
europepmc   +1 more source

Towards a dialogic management of cognitive competence [PDF]

open access: yes
In this paper we examine the nature of the competences needed for promoting innovation and change. Taking our experiences as the starting point, we examined the literature and interviewed managers and those responsible for innovation in enterprises and ...
Aline Dupouy   +3 more
core  

A theoretical model for design in Management science : the paradigm shift in the design profession for management as a constraint to management science as an opportunity [PDF]

open access: yes, 2008
Design Management has changed greatly since 1990 Peter Gorb definition .The purpose of this paper is to synthetize the various models of Design Management and to explain their limits in front of the paradigm shift of the design profession, changing “from
Borja de Mozota, B
core  

Validation of a Genetic Risk Score Combined With Clinical Variables for Predicting Pulmonary Fibrosis in Early Rheumatoid Arthritis

open access: yesArthritis Care &Research, EarlyView.
Objective Pulmonary fibrosis (PF) is a severe extra‐articular manifestation of rheumatoid arthritis (RA). This study aimed to externally validate a genetic risk score (GRS) and a combined risk score (CRS) for predicting the risk of RA‐associated PF in an independent cohort of patients with early RA.
Mikael Brink   +3 more
wiley   +1 more source

Responsible innovation in health and health system sustainability: Insights from health innovators' views and practices. [PDF]

open access: yesHealth Serv Manage Res, 2022
Lehoux P   +4 more
europepmc   +1 more source

Performance Characteristics of Anti–Collagen II Antibodies in Relapsing Polychondritis and Related Diseases: Prospective Analysis, Systematic Review, and Meta‐Analysis

open access: yesArthritis Care &Research, EarlyView.
Objective Relapsing polychondritis (RP) is a rare disease defined by recurrent cartilaginous inflammation. Anti–collagen II (Col2) antibodies have been proposed as a diagnostic biomarker for RP, but their performance characteristics are not well defined.
Karyssa Stonick   +6 more
wiley   +1 more source

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