Results 131 to 140 of about 2,951,975 (308)
Comparative analysis of chloroplast genomes from 14 genera of Thymelaeaceae revealed variation in gene content, ranging from 128 to 142 genes, primarily influenced by IR expansion/contraction events and pseudogenization of ndhF, ndhI, and ndhG. Two large inversions were detected within the large single‐copy region, including a synapomorphic inversion ...
Abdullah +8 more
wiley +1 more source
RESPONSIBLE FINANCIAL INNOVATION IN BANKS: COMMITTEES OF NEW PRODUCTS
Organizations adapt to the environment using new management tools as part of the evolution process. Additionally, if complexity is incorporated, the theory help to understand behaviour of agents within an organization.
Casparri, María Teresa +2 more
doaj
CHAU VAN LIEM DURING THE CAMPAIGN TO ESTABLISH THE COMMUNIST PARTY OF VIETNAM IN 1930
The article focuses on clarifying role of Chau Van Liem (1902-1930), that as the highest leader of the Annam Communist Party organization in Cochinchina, has many urgent and responsible activities, making an important contribution to preparing the ...
Le Van Dung, Dang Hoang Sang
doaj +1 more source
Naked cuticle is essential for Drosophila wing development beyond Wingless signaling
Naked cuticle (Nkd), a Wnt signaling inhibitor, assumes extensive roles in Drosophila wing development. Overexpressing Nkd causes smaller, crumpled wings, while also perturbing multiple signaling pathways and developmental genes. A specific region (R1S) is critical for Nkd's function as a signaling integrator, offering new insights for studying its ...
Rui Wang, Ping Wang
wiley +1 more source
Analysis of Treacher Collins syndrome 4‐associated mutations in Schizosaccharomyces pombe
Fission yeast models carrying Treacher Collins syndrome type 4‐associated mutations reveal that impaired processivity of RNA polymerase I leads to defective rRNA transcription. This study highlights the essential role of a conserved arginine residue in Pol I elongation and provides mechanistic insight into the pathogenesis of ribosomopathies.
Kei Kawakami, Hiroaki Kato
wiley +1 more source
SIRT4 positively regulates autophagy via ULK1, but independently of HDAC6 and OPA1
Cells expressing SIRT4 (H161Y), a catalytically inactive mutant of the sirtuin SIRT4, fail to upregulate LC3B‐II and exhibit a reduced autophagic flux under stress conditions. Interestingly, SIRT4(H161Y) promotes phosphorylation of ULK1 at S638 and S758 that are associated with inhibition of autophagy initiation.
Isabell Lehmkuhl +13 more
wiley +1 more source
Clinical analysis reveals significant dysregulation of FGFRL1 in esophageal cancer (EC) patients. RNAi‐coupled next‐generation sequencing (NGS) and in vitro study reveal FGFRL1‐mediated EC progression via EMT, PI3K/Akt, and Notch pathways. Functional assays confirm its role in tumor growth, migration, and invasion.
Aprajita Srivastava +3 more
wiley +1 more source
MAPS - a computerized management analysis and planning system [PDF]
Program lists work structure of projects at all levels. System integrates work item, its schedule, its status against the schedule, responsible personnel, and explanatory comments. structure of MAPS promotes natural organization of project work elements,
Packe, D. R., Raffaeli, G. A.
core +3 more sources
An assessment of counseling needs among international graduate students: implications for university students’ programmes and services [PDF]
Interest in going abroad for studies is getting higher in Indonesia. But foreign students will find it even more problematic, because they face both the normal adjustment problems of studying in university plus adjustment problems of adapting to a ...
Rahaju, Soerjantini
core
We investigated the toxicity of 12 active compounds commonly found in herbal weight loss supplements (WLS) using human liver and colon cell models. Epigallocatechin‐3‐gallate was the only compound showing significant toxicity. Metabolic profiling revealed protein degradation, disrupted energy and lipid metabolism suggesting that the inclusion of EGCG ...
Emily C. Davies +3 more
wiley +1 more source

