Results 141 to 150 of about 1,193,547 (261)
OpenPING: A Reflective Middleware for the Construction of Adaptive Networked Game Applications [PDF]
, 2004 The emergence of distributed Virtual Reality (VR) applications that run over the Internet has presented networked game application designers with new challenges.
Blair, Gordon S., Okanda, P.
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Molecular Oncology, EarlyView.The cancer problem is increasing globally with projections up to the year 2050 showing unfavourable outcomes in terms of incidence and cancer‐related deaths. The main challenges are prevention, improved therapeutics resulting in increased cure rates and enhanced health‐related quality of life.
Ulrik Ringborg +43 more
wiley +1 more source
Immigrants Responsiveness to Labor Market Conditions [PDF]
Using data from the Spanish Labor Force Survey (Encuesta de Población Activa) from 1999 through 2004, we explore the role of regional employment opportunities in explaining the increasing immigrant flows of recent years despite the limited internal ...
Amuedo Dorantes, Catalina +1 more
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Cell surface interactome analysis identifies TSPAN4 as a negative regulator of PD‐L1 in melanoma
Molecular Oncology, EarlyView.Using cell surface proximity biotinylation, we identified tetraspanin TSPAN4 within the PD‐L1 interactome of melanoma cells. TSPAN4 negatively regulates PD‐L1 expression and lateral mobility by limiting its interaction with CMTM6 and promoting PD‐L1 degradation.
Guus A. Franken +7 more
wiley +1 more source
Asymmetric Response to Monetary Policy Surprises at the Long-End of the Yield Curve [PDF]
This paper provides a dynamic analysis of the responsiveness of asset markets to monetary policy path revisions. In an era of increased transparency and gradualism in policy making, one might expect an increased response to path revisions in asset ...
Kamil Yilmaz, Selva Demiralp
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Molecular Oncology, EarlyView.Pharmacologic ascorbate (vitamin C) increases ROS, disrupts cellular metabolism, and induces DNA damage in CRPC cells. These effects sensitize tumors to PARP inhibition, producing synergistic growth suppression with olaparib in vitro and significantly delayed tumor progression in vivo. Pyruvate rescue confirms ROS‐dependent activity.
Nicolas Gordon +13 more
wiley +1 more source
Wage responsiveness and labor market disequilibrium [PDF]
The objectives of this paper are : (i) to empirically probe on the validity of the hypothesis that wages are relatively unresponsive to labor market disequlibrium; and (ii) to investigate whether the dramatically diverse rates of unemployment observed ...
Lopez, Ramon E., Riveros, Luis A.
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Supervisor Cultural Responsiveness and Unresponsiveness in Cross-Cultural Supervision [PDF]
, 2006 Thirteen supervisees’ of color and 13 European American supervisees’ experiences of culturally responsive and unresponsive cross-cultural supervision were studied using consensual qualitative research.
Burkard, Alan W. +7 more
core +1 more source
Plecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin
Molecular Oncology, EarlyView.The ruthenium‐based metallodrug plecstatin exerts its anticancer effect in hepatocellular carcinoma (HCC) primarily through selective targeting of plectin. By disrupting plectin‐mediated cytoskeletal organization, plecstatin inhibits anchorage‐dependent growth, cell polarization, and tumor cell dissemination.
Zuzana Outla +10 more
wiley +1 more source