Results 61 to 70 of about 1,193,547 (261)

The Evolution of Representative Claim-Making by the Chinese Communist Party: From Mao to Xi (1949–2019)

open access: yesPolitics and Governance, 2019
This article traces the evolution of representative claim-making by the Chinese Communist Party (CCP) since the proclamation of the People’s Republic of China in 1949 up to the present day.
Emilie Frenkiel, Anna Shpakovskaya
doaj   +1 more source

Moral Hedging and Responding to Reasons [PDF]

open access: yes, 2019
In this paper, I argue that the fetishism objection to moral hedging fails. The objection rests on a reasons-responsiveness account of moral worth, according to which an action has moral worth only if the agent is responsive to moral reasons. However, by
Hicks, Amelia
core  

Interplay between circadian and other transcription factors—Implications for cycling transcriptome reprogramming

open access: yesFEBS Letters, EarlyView.
This perspective highlights emerging insights into how the circadian transcription factor CLOCK:BMAL1 regulates chromatin architecture, cooperates with other transcription factors, and coordinates enhancer dynamics. We propose an updated framework for how circadian transcription factors operate within dynamic and multifactorial chromatin landscapes ...
Xinyu Y. Nie, Jerome S. Menet
wiley   +1 more source

The MS Symptom and Impact Diary (MSSID): psychometric evaluation of a new instrument to measure the day to day impact of multiple sclerosis [PDF]

open access: yes, 2004
OBJECTIVES: This study aimed to develop further a diary originally devised to measure the impact of multiple sclerosis (MS) as part of a cost utility study of beta interferon, and to evaluate its reliability, validity, and responsiveness in an ...
Ford, H   +3 more
core   +2 more sources

Disordered but rhythmic—the role of intrinsic protein disorder in eukaryotic circadian timing

open access: yesFEBS Letters, EarlyView.
Unstructured domains known as intrinsically disordered regions (IDRs) are present in nearly every part of the eukaryotic core circadian oscillator. IDRs enable many diverse inter‐ and intramolecular interactions that support clock function. IDR conformations are highly tunable by post‐translational modifications and environmental conditions, which ...
Emery T. Usher, Jacqueline F. Pelham
wiley   +1 more source

Assessing health systems' responsiveness in tackling COVID-19 pandemic

open access: yesIndian Journal of Public Health, 2020
Health systems' responsiveness is the key to addressing infectious disease threats such as pandemics. The article outlines an assessment of health systems based on World Health Organization's building blocks for select countries.
Sutapa Bandyopadhyay Neogi, G S Preetha
doaj   +1 more source

A generalised approach to torsionality maximisation in longitudinal-torsional ultrasonic devices [PDF]

open access: yes, 2011
A longitudinal-torsional vibration mode has many applications in ultrasonic systems. Obtaining this behaviour could be achieved either by coupling the longitudinal and torsional modes or by degenerating the longitudinal mode, but the results may be ...
Al-Budairi, Hassan   +2 more
core  

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

open access: yesFEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe   +3 more
wiley   +1 more source

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