Results 91 to 100 of about 872,123 (298)
WEB-SERVICE. RESTFUL ARCHITECTURE
Автоматизация технологических и бизнес-процессов, 2018 Network technology for interaction between two applications via the HTTP protocol was considered in article.When client works with REST API - it means it works with "resources", and in SOAP work is performed with operations.
M. Melnichuk, Yu. Kornienko, O. Boytsova
doaj +1 more source
Finding novel vulnerabilities of hypomorphic BRCA1 alleles
Molecular Oncology, EarlyView.Synthetic lethality screens performed to identify novel vulnerabilities often model complete gene loss, thereby overlooking patient‐derived hypomorphic mutations. In this study, we have performed genome‐wide CRISPR screens on BRCA1 hypomorphic mutations, showing BRCA1I26A behaves like wild‐type, while BRCA1R1699Q mimics deficiency. Furthermore, we have
Anne Schreuder +10 more
wiley +1 more source
ChEMBL Beaker: A Lightweight Web Framework Providing Robust and Extensible Cheminformatics Services
Challenges, 2014 ChEMBL Beaker is an open source web framework, exposing a versatile chemistry-focused API (Application Programming Interface) to support the development of new cheminformatics applications. This paper describes the current functionality offered by Beaker
Michał Nowotka +3 more
doaj +1 more source
MITF maintains genome stability in nonmelanocyte lineages
Molecular Oncology, EarlyView.MITF is essential for melanocyte survival and acts as an oncogene in 10%–20% of melanomas. We show that MITF depletion causes genome instability in nonmelanocytic cells, leading to LATS2‐mediated P53 activation, cell cycle arrest, and apoptosis. This study highlights the role of MITF as a genome maintenance factor beyond the melanocyte lineage. Created
Drifa H. Gudmundsdottir +13 more
wiley +1 more source
Informes Científicos y Técnicos (Universidad Nacional de la Patagonia Austral)La formulación de consultas ambiguas en plataformas como ChatGPT limita la efectividad de los sistemas de inteligencia artificial para generar respuestas relevantes y precisas.
Lucas GOROSITO, Sandra CASAS
doaj +5 more sources
Cybersäkert REST API för produktionsstyrningssystem
, 2023 Legacy systems are still in widespread use, especially in corporate settings and factories. They often use proprietary communication protocols, making it harder to integrate them with new software and third-party applications.
Lönnbäck, Otto
core +1 more source
An Analysis of RESTful APIs Offerings in the Industry [PDF]
, 2017 Ministerio de Educación, Cultura y Deportes FPU15 ...
Antonio Gamez-Diaz +2 more
openaire +4 more sources
Molecular Oncology, EarlyView.The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka +9 more
wiley +1 more source
Oncogenic DMTF1β promotes cancer cell motility by regulating autophagy through ULK1 stabilization
Molecular Oncology, EarlyView.In the current study, we demonstrate that the oncogene DMTF1β regulates ULK1 stability by reducing its proteasomal degradation in cancer cells. This stabilization enables ULK1 to induce autophagy, which in turn facilitates cancer cell migration. Consequently, reduced DMTF1β levels lead to decreased autophagy and impaired cancer cell migration.
Jun Xu +13 more
wiley +1 more source