FEBS Letters, EarlyView.Enteropathogenic E. coli (EPEC) infects the human intestinal epithelium, resulting in severe illness and diarrhoea. In this study, we compared the infection of cancer‐derived cell lines with human organoid‐derived models of the small intestine. We observed a delayed in attachment, inflammation and cell death on primary cells, indicating that host ...
Mastura Neyazi +5 more
wiley +1 more source
Plasmodium falciparum gametogenesis essential protein 1 (GEP1) is a transmission‐blocking target
FEBS Letters, EarlyView.This study shows Plasmodium falciparum GEP1 is vital for activating sexual stages of malarial parasites even independently of a mosquito factor. Knockout parasites completely fail gamete formation even when a phosphodiesterase inhibitor is added. Two single‐nucleotide polymorphisms (V241L and S263P) are found in 12%–20% of field samples.
Frederik Huppertz +5 more
wiley +1 more source
The creation of the world in time according to Fakhr al-Razi [PDF]
Kom: Časopis za Religijske Nauke, 2017 The eternity or creation of the world in time is a question that many scholars from different fields have tackled, regardless of their religious affiliation. In the Islamic tradition, theologians generally affirmed the temporal creation of the world.
Husain Agha Shiraz
doaj
Thalamo-cortical network activity between migraine attacks: Insights from MRI-based microstructural and functional resting-state network correlation analysis [PDF]
, 2016 Gianluca Coppola +11 more
openalex +1 more source
FEBS Letters, EarlyView.Atovaquone is an antimalarial requiring potentiation for sufficient efficacy. We pursued strategies to enhance its activity, showing that 4‐nitrobenzoate inhibits 4‐hydroxybenzoate polyprenyltransferase, decreasing ubiquinone biosynthesis. Since atovaquone competes with ubiquinol in mitochondria, 4‐nitrobenzoate facilitates its action, potentiating ...
Ignasi Bofill Verdaguer +7 more
wiley +1 more source
LifeBackground: Short-term (5 min) heart rate variability (HRV) analysis is widely used in assessing autonomic nervous system activity during exercise. While shortening the HRV measurement duration can help improve its application efficiency, its accuracy ...
Kai Jin +5 more
doaj +1 more source
Of mice and men: opposing effects of nicotinamide riboside on skeletal muscle physiology at rest and during exercise [PDF]
, 2021 Laís S. S. Ferreira +1 more
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Organoids in pediatric cancer research
FEBS Letters, EarlyView.Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley +1 more source
Theoretical and methodological approaches to the problem of students' health in algorithms of recreation measures. [PDF]
Pedagogìka, Psihologìâ ta Mediko-bìologìčnì Problemi Fìzičnogo Vihovannâ ì Sportu, 2011 In the article is expounded about health and its basic constituents: physical, psychical and social. Description is given to physical development of man and its physical preparedness, physical form and trained, physical activity and functional readiness.
Zaytzev V.P. +2 more
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Replication of Resting State-Task Network Correspondence and Novel Findings on Brain Network Activation During Task fMRI in the Human Connectome Project Study [PDF]
, 2018 Lisa D. Nickerson
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