Results 71 to 80 of about 1,463,699 (265)
Cryptochrome and PAS/LOV proteins play intricate roles in circadian clocks where they act as both sensors and mediators of protein–protein interactions. Their ubiquitous presence in signaling networks has positioned them as targets for small‐molecule therapeutics. This review provides a structural introduction to these protein families.
Eric D. Brinckman +2 more
wiley +1 more source
Welfare studies are increasingly involving the application of Precision Livestock Farming (PLF) sensors, rather than the use of animal-based indicators directly assessed.
Gaia Pesenti Rossi +4 more
doaj +1 more source
This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva +5 more
wiley +1 more source
Sandrart.net describes itself as a 'research platform for the history of art and culture of the 17th century'. It is a digital edition of Joachim von Sandrart’s magnum opus, the 'Teutsche Academie', published between 1675 and 1680 in a German and between
Patrick Sahle
doaj +1 more source
In situ molecular organization and heterogeneity of the Legionella Dot/Icm T4SS
We present a nearly complete in situ model of the Legionella Dot/Icm type IV secretion system, revealing its central secretion channel and identifying new components. Using cryo‐electron tomography with AI‐based modeling, our work highlights the structure, variability, and mechanism of this complex nanomachine, advancing understanding of bacterial ...
Przemysław Dutka +11 more
wiley +1 more source
Background: Short-term (5 min) heart rate variability (HRV) analysis is widely used in assessing autonomic nervous system activity during exercise. While shortening the HRV measurement duration can help improve its application efficiency, its accuracy ...
Kai Jin +5 more
doaj +1 more source
Sequence determinants of RNA G‐quadruplex unfolding by Arg‐rich regions
We show that Arg‐rich peptides selectively unfold RNA G‐quadruplexes, but not RNA stem‐loops or DNA/RNA duplexes. This length‐dependent activity is inhibited by acidic residues and is conserved among SR and SR‐related proteins (SRSF1, SRSF3, SRSF9, U1‐70K, and U2AF1).
Naiduwadura Ivon Upekala De Silva +10 more
wiley +1 more source
I will consider, first, the positive charge of energeia in Aristotle, who identified it with the actuality of the actual. Then, I will pay attention to the negative charge that re-signifies the term, bestowing on it the exact opposite sense of ...
Michael Marder
doaj +1 more source
’Blessed are the Dead Which Die in the Lord’: Andrew Fuller on the Beatific Vision
This essay examines the funeral sermon given by the Baptist theologian Andrew Fuller (1754–1815) for his friend and deacon Beeby Wallis in 1792 as a vantage-point from which to pursue reflection on Fuller’s concept of heaven and the beatific vision.
Haykin Michael A. G., Burns E. D.
doaj +1 more source
Performance evaluation of microservices communication with REST, GraphQL, and gRPC [PDF]
Microservice architecture has become the design paradigm for creating scalable and maintainable software systems. Selecting the proper communication protocol in microservices is critical to achieving optimal system performance.
Muhammad Niswar +3 more
doaj +1 more source

