Results 11 to 20 of about 70,989 (244)
Restenosis, defined as the re-narrowing of an arterial lumen after revascularization, represents an increasingly important issue in clinical practice.
Scott Wilson +10 more
doaj +5 more sources
Restenosis begets restenosis: implications for stent selection [PDF]
Identifying the risk for restenosis is of critical importance in the stent selection process of patients undergoing percutaneous coronary intervention (PCI). Therefore, we sought to determine if a history of clinical recurrence (CR) after PCI increases the risk of CR after treatment of a de novo lesion in another coronary artery.We retrospectively ...
Wijpkema, J. S. +5 more
openaire +3 more sources
Design and testing of hydrophobic core/hydrophilic shell nano/micro particles for drug-eluting stent coating [PDF]
In this study, we designed a novel drug-eluting coating for vascular implants consisting of a core coating of the anti-proliferative drug docetaxel (DTX) and a shell coating of the platelet glycoprotein IIb/IIIa receptor monoclonal antibody SZ-21.
A Arsiwala +62 more
core +1 more source
Bindarit inhibits human coronary artery smooth muscle cell proliferation, migration and phenotypic switching [PDF]
Bindarit, a selective inhibitor of monocyte chemotactic proteins (MCPs) synthesis, reduces neointimal formation in animal models of vascular injury and recently has been shown to inhibit in-stent late loss in a placebo-controlled phase II clinical trial.
Angelo Guglielmotti +12 more
core +7 more sources
In the past decade, tremendous progress has been made in reducing the incidence of restenosis with the advent of the drug-eluting stent (DES). With “plain old balloon angioplasty,” rates of acute and chronic vessel occlusion were unacceptably high at ≈30% to 60%, secondary to acute and chronic recoil and constrictive remodeling.
Farooq, V +2 more
openaire +4 more sources
Pathogen burden, inflammation, proliferation and apoptosis in human in-stent restenosis - Tissue characteristics compared to primary atherosclerosis [PDF]
Pathogenic events leading to in-stent restenosis (ISR) are still incompletely understood. Among others, inflammation, immune reactions, deregulated cell death and growth have been suggested. Therefore, atherectomy probes from 21 patients with symptomatic
Abdelmegui AE +24 more
core +1 more source
Robust optimization of cardiovascular stents: A comparison of methods [PDF]
This is the post-print version of the Article. The official published version can be accssed from the links below. Copyright @ 2004 Taylor & FrancisModern engineering design contains both creative and analytic components.
Atherton, MA, Bates, RA
core +1 more source
Inhibition of in-stent stenosis by oral administration of bindarit in porcine coronary arteries [PDF]
<p><b>Objective:</b> We have previously demonstrated that bindarit, a selective inhibitor of monocyte chemotactic proteins (MCPs), is effective in reducing neointimal formation in rodent models of vascular injury by reducing smooth ...
Baker, A.H. +10 more
core +1 more source
Hyperhomocysteinemia and recurrent carotid stenosis
Background Hyperhomocysteinemia has been identified as a potential risk for atherosclerotic disease in epidemiologic studies. This study investigates the impact of elevated serum homocysteine on restenosis after carotid endarterectomy (CEA). Methods In a
Liewald Florian +3 more
doaj +1 more source
BackgroundIncreasing evidence suggests that insulin resistance is linked to cardiovascular disease and atherosclerosis. The triglyceride–glucose (TyG) index has proven to be a convincing marker to quantitatively evaluate insulin resistance.
Shan-shan Zhao +4 more
doaj +1 more source

