Results 291 to 300 of about 119,230 (327)
Some of the next articles are maybe not open access.
Current Treatment Options in Cardiovascular Medicine, 2001
Angiographic restenosis occurs in 30% to 50% of patients after percutaneous transluminal coronary angioplasty (PTCA) with 20% to 30% target vessel revascularization at one year, and is associated with increased morbidity, mortality and health care costs. Intracoronary stents are the first line of therapy against restenosis after angioplasty.
Paul S. Teirstein +2 more
openaire +3 more sources
Angiographic restenosis occurs in 30% to 50% of patients after percutaneous transluminal coronary angioplasty (PTCA) with 20% to 30% target vessel revascularization at one year, and is associated with increased morbidity, mortality and health care costs. Intracoronary stents are the first line of therapy against restenosis after angioplasty.
Paul S. Teirstein +2 more
openaire +3 more sources
Current Cardiology Reports, 2000
This review provides an overview of candidate genes that are currently being evaluated for genetic strategies in vascular gene therapy. We discuss treatment strategies that have proven efficacious in limiting postinterventional restenosis through evaluation with in vivo model systems.
Roy C. Smith, Kenneth Walsh
openaire +3 more sources
This review provides an overview of candidate genes that are currently being evaluated for genetic strategies in vascular gene therapy. We discuss treatment strategies that have proven efficacious in limiting postinterventional restenosis through evaluation with in vivo model systems.
Roy C. Smith, Kenneth Walsh
openaire +3 more sources
The Journal of Cardiovascular Surgery
Endovascular arterial recanalization has become the mainstay therapy for peripheral arterial occlusive disease. Although immediate technical success is achieved in greater than 90% of cases, longer-term results continue to vary based on the clinical presentation, and the treated target lesion.
El Khoury, Rym +5 more
openaire +3 more sources
Endovascular arterial recanalization has become the mainstay therapy for peripheral arterial occlusive disease. Although immediate technical success is achieved in greater than 90% of cases, longer-term results continue to vary based on the clinical presentation, and the treated target lesion.
El Khoury, Rym +5 more
openaire +3 more sources
Approaches for prevention of restenosis
Journal of Biomedical Materials Research Part B: Applied Biomaterials, 2007AbstractCoronary artery disease is characterized by a narrowing (stenosis) of the arteries that supply blood to the tissue of the heart. Continued restriction of blood flow manifests itself as angina and ultimately myocardial infarction (heart attack) for the patient.
Amir Kraitzer +2 more
openaire +3 more sources
2007
The human genome sequence is now known. With the completion of the human genome project, focus has shifted to the immense task of understanding the function of genes and their roles in disease processes. The proteome is defined as the complement of proteins expressed by the genome. The ultimate expression of the genome is the proteome.
Santhi K. Ganesh, Elizabeth G. Nabel
openaire +2 more sources
The human genome sequence is now known. With the completion of the human genome project, focus has shifted to the immense task of understanding the function of genes and their roles in disease processes. The proteome is defined as the complement of proteins expressed by the genome. The ultimate expression of the genome is the proteome.
Santhi K. Ganesh, Elizabeth G. Nabel
openaire +2 more sources
The Genomics of Restenosis [PDF]
, 2007 Interventional cardiology took off in 1977, with the development of percutaneous coronary balloon angioplasty (1). Despite immediate success in regaining vessel patency, long-term results were undermined by luminal loss secondary to the vessel injury induced by the balloon (2,3).
Thomas W Johnson, Karl R. Karsch
openaire +1 more source
Pharmacotherapy of Restenosis [PDF]
, 2007 Restenosis has been recognized as the main limitation of coronary balloon angioplasty since its introduction in 1978. The main causes were the constrictive vessel remodeling (acute and chronic) and the neointimal hyperplasia. The coronary stents were introduced in 1986 and reduced restenosis from 30–40% to 15–20% in certain type of lesions by ...
Pim J. de Feyter, Georgios Sianos
openaire +1 more source
, 2018 Restenosis is an arterial wall healing response to mechanical injury at the site of a previously treated coronary segment. In-stent restenosis (ISR) is an angiographic diagnosis, defined as recurrent diameter stenosis >50% within a stent or at its edges (5 mm segments proximal and distal to the stent).
Roisin Colleran, Robert A. Byrne
openaire +1 more source
New England Journal of Medicine, 2002
Over the past two decades, percutaneous coronary intervention has revolutionized the treatment of symptomatic coronary artery disease, sparing countless patients the need for surgical revascularization. This year, up to a million procedures are likely to be performed in North America alone. The success of percutaneous coronary intervention has been due
openaire +3 more sources
Over the past two decades, percutaneous coronary intervention has revolutionized the treatment of symptomatic coronary artery disease, sparing countless patients the need for surgical revascularization. This year, up to a million procedures are likely to be performed in North America alone. The success of percutaneous coronary intervention has been due
openaire +3 more sources
Trends in Cardiovascular Medicine, 1994
Percutaneous transluminal coronary angioplasty is a widely used technique for recanalizing arteries that are occluded by atherosclerotic plaque, but its usefulness is limited by the occurrence ofrestenosis in a high proportion of patients. The development of new therapies for this currently intractable problem will be facilitated by the use of animal ...
openaire +3 more sources
Percutaneous transluminal coronary angioplasty is a widely used technique for recanalizing arteries that are occluded by atherosclerotic plaque, but its usefulness is limited by the occurrence ofrestenosis in a high proportion of patients. The development of new therapies for this currently intractable problem will be facilitated by the use of animal ...
openaire +3 more sources