Results 21 to 30 of about 2,693 (98)

Short-term caloric restriction or resveratrol supplementation alters large-scale brain network connectivity in male and female rats

Frontiers in Nutrition
IntroductionDietary interventions such as caloric restriction (CR) exert positive effects on brain health. Unfortunately, poor compliance hinders the success of this approach.
Judith R. A. van Rooij, Judith R. A. van Rooij, Monica van den Berg, Monica van den Berg, Tamara Vasilkovska, Johan Van Audekerke, Johan Van Audekerke, Lauren Kosten, Daniele Bertoglio, Daniele Bertoglio, Mohit H. Adhikari, Mohit H. Adhikari, Marleen Verhoye, Marleen Verhoye   +13 more
doaj   +1 more source

Alterations of the nigrostriatal pathway in a 6-OHDA rat model of Parkinson's disease evaluated with multimodal MRI. [PDF]

PLoS ONE, 2018
Parkinson's disease is characterized by neurodegeneration of the dopaminergic neurons in the substantia nigra pars compacta. The 6-hydroxydopamine (6-OHDA) rat model has been used to study neurodegeneration in the nigro-striatal dopaminergic system.
Vincent Perlbarg, Justine Lambert, Benjamin Butler, Mehdi Felfli, Romain Valabrègue, Anne-Laure Privat, Stéphane Lehéricy, Alexandra Petiet   +7 more
doaj   +1 more source

Hypoxia’s Impact on Hippocampal Functional Connectivity: Insights from Resting-State fMRI Studies

Brain Sciences
The hippocampus is one of the brain’s most vulnerable structures to hypoxia, playing a crucial role in memory and spatial navigation. This sensitivity makes it a key region for understanding the effects of hypoxia on brain connectivity.
Julia Micaux, Abir Troudi Habibi, Franck Mauconduit, Marion Noulhiane   +3 more
doaj   +1 more source

Recent developments in representations of the connectome

NeuroImage, 2021
Research into the human connectome (i.e., all connections in the human brain) with the use of resting state functional MRI has rapidly increased in popularity in recent years, especially with the growing availability of large-scale neuroimaging datasets.
Janine D. Bijsterbosch, Sofie L. Valk, Danhong Wang, Matthew F. Glasser   +3 more
doaj   +1 more source

A Depolarizing Leak in Sodium Bicarbonate Cotransporter NBCe1 Causes Brain Edema

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objectives SLC4A4 encodes electrogenic sodium bicarbonate cotransporter NBCe1, prominently expressed in kidney and brain. Recessive loss‐of‐function variants in SLC4A4 cause proximal renal tubular acidosis, no brain edema. In the brain, NBCe1 is expressed by astrocytes, where it regulates pH and mediates astrocyte volume changes.
Quinty Bisseling, Mark D. Parker, Sven Kerst, Richard A. Pasternack, Jacob Tondreau, Marjolein Breur, Gemma M. van Rooijen‐van Leeuwen, Davide Tonduti, Ettore Salsano, Alejandra Darling, Joanna A. E. van Wijk, Susanna Törnroth‐Horsefield, Marianna Bugiani, Petra J. W. Pouwels, Quinten Waisfisz, Marjo S. van der Knaap, Rogier Min   +16 more
wiley   +1 more source

Resting-State Functional MRI in Dyslexia: A Systematic Review

Biomedicines
Background/Objectives: The present review addresses and systematically analyses the most frequently reported neuropsychological and functional connectivity (FC) alterations in individuals with dyslexia compared to controls.
Bruce Martins, Isabel A. B. Verrone, Mariana M. I. Sakamoto, Mariana Y. Baba, Melissa E. Yvata, Katerina Lukasova, Mariana P. Nucci   +6 more
doaj   +1 more source

Effectiveness of rTMS on Working Memory and Inhibitory Impairments in Patients With Post‐Stroke Executive Deficits

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Considerable efforts have been dedicated to developing effective treatments for post‐stroke executive impairment (PSEI), among which repetitive transcranial magnetic stimulation (rTMS) has shown great potential. This study aimed to investigate the therapeutic effects of high‐frequency rTMS on working memory (WM) and response ...
Mengting Lao, Rongwei Du, Zhujun Wang, Yang Gao, Meiling Cheng, Xianglong Wang, Wen Wu   +6 more
wiley   +1 more source

The YOUth cohort study: MRI protocol and test-retest reliability in adults

Developmental Cognitive Neuroscience, 2020
The YOUth cohort study is a unique longitudinal study on brain development in the general population. As part of the YOUth study, 2000 children will be included at 8, 9 or 10 years of age and planned to return every three years during adolescence ...
Elizabeth E.L. Buimer, Pascal Pas, Rachel M. Brouwer, Martijn Froeling, Hans Hoogduin, Alexander Leemans, Peter Luijten, Bastiaan J. van Nierop, Mathijs Raemaekers, Hugo G. Schnack, Jalmar Teeuw, Matthijs Vink, Fredy Visser, Hilleke E. Hulshoff Pol, René C.W. Mandl   +14 more
doaj   +1 more source

Memory and Resting‐State Connectivity in Acute Transient Global Amnesia: A Case–Control fMRI Study

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background and Objectives Transient global amnesia (TGA) is a striking model of isolated amnesia. While hippocampal lesions are well described, the network‐level mechanisms and the precise neuropsychological profile remain debated. Our objective was thus to characterize functional and neuropsychological correlates of acute TGA and their ...
Elias El Otmani, Emmanuel Barbeau, Béatrice Lemesle, Emilie Milongo‐Rigal, Sophie Fernandez, Sandrine Charpentier, Jean‐François Albucher, Nicolas Raposo, Fabrice Bonneville, Patrice Péran, Jérémie Pariente   +10 more
wiley   +1 more source

Presbycusis Disrupts Spontaneous Activity Revealed by Resting-State Functional MRI

Frontiers in Behavioral Neuroscience, 2018
Purpose: Presbycusis, age-related hearing loss, is believed to involve neural changes in the central nervous system, which is associated with an increased risk of cognitive impairment.
Yu-Chen Chen, Yu-Chen Chen, Huiyou Chen, Liang Jiang, Fan Bo, Jin-Jing Xu, Cun-Nan Mao, Richard Salvi, Xindao Yin, Guangming Lu, Jian-Ping Gu   +10 more
doaj   +1 more source