Results 91 to 100 of about 361,308 (287)

Suppression of lung adenocarcinoma migration through organelle alkalization by human lactoferrin – albumin fusion

FEBS Open Bio, EarlyView.
This paper reveals how human lactoferrin–albumin fusion (hLF‐HSA) potently suppresses lung adenocarcinoma cell migration. hLF‐HSA upregulates NHE7, leading to Golgi alkalization, disruption of the Golgi secretome, downregulation of MMP1, and reversal of EMT. These findings suggest a novel Golgi‐targeting strategy to suppress cancer cell migration.
Hana Nopia, Masahiro Kimura, Daisuke Kurimoto, Atsushi Sato   +3 more
wiley   +1 more source

Alterations of Directional Connectivity among Resting-State Networks in Alzheimer Disease [PDF]

, 2013
BACKGROUND AND PURPOSE: AD has been documented as a kind of disconnection syndrome by functional neuroimaging studies. The primary focus of this study was to examine, with the use of resting-state fMRI, whether AD would impact connectivity among RSNs ...
Wu, X (reprint author), Beijing Normal Univ, Sch Informat Sci & Technol, Beijing 100875, Peoples R China., Li, R., Wu, X., Fleisher, A. S., Chen, K., Yao, L., Reiman, E. M.   +6 more
core  

Spectral signatures of reorganised brain networks in disorders of consciousness [PDF]

, 2014
Theoretical advances in the science of consciousness have proposed that it is concomitant with balanced cortical integration and differentiation, enabled by efficient networks of information transfer across multiple scales. Here, we apply graph theory to
Valdas Noreika (645566), Bekinschtein Tristan A., Daniela Cabezas-Soto, Williams, Guy B, Bekinschtein, Tristan A., Arnatkeviciute, Aurina, Chennu Srivas, Adrian M Owen, Francisco Olivares, Bekinschtein, Tristan A, Martin M. Monti (473279), Judith Allanson, Olivares, Francisco, Monti, Martin M, Paola Finoia (645563), Paola Finoia, Canales-Johnson, Andrés, Valdas Noreika, Finoia Paola, Menon, David K, Srivas Chennu, Canales-Johnson Andrés, Guy B Williams, Noreika, Valdas, Olivares Francisco, Aurina Arnatkeviciute (645567), David K Menon, Andrés Canales-Johnson, John D Pickard, Adrian M. Owen (49476), Judith Allanson (645565), Owen, Adrian M, Aurina Arnatkeviciute, Pickard John D., Chennu, Srivas, Cabezas-Soto, Daniela, Monti, Martin M., Andrés Canales-Johnson (343746), Martin M Monti, Menon David K., Allanson Judith, Noreika Valdas, Tristan A. Bekinschtein (589475), Williams, Guy B., Owen Adrian M., Tristan A Bekinschtein, Guy B. Williams (121897), Pickard, John D., Kamau Evelyn, Daniela Cabezas-Soto (645569), Francisco Olivares (645568), Evelyn Kamau (645564), John D. Pickard (645570), Monti Martin M., Pickard, John D, Finoia, Paola, Owen, Adrian M., Evelyn Kamau, Srivas Chennu (297764), David K. Menon (236037), Williams Guy B., Kamau, Evelyn, Menon, David K., Arnatkeviciute Aurina, Cabezas-Soto Daniela, Allanson, Judith   +65 more
core   +1 more source

Pathways and pitfalls: a qualitative study of student experiences in biomedical science education

FEBS Open Bio, EarlyView.
Biomedical science students from underrepresented backgrounds face barriers including financial strain, disrupted laboratory access and cultural exclusion. Peer networks provide vital support when institutional systems are difficult to navigate. To create inclusive learning environments and achieve academic success, educators should blend active, hands‐
Olivia J. Russell, Cassy Ross, Panagiota S. Filippou, Bruno Silvester Lopes, Dominic Gilchrist, Paul Dean, Kamar Ameen‐Ali, Tora K. Smulders‐Srinivasan, Ahmad A. Khundakar   +8 more
wiley   +1 more source

Feasibility and Tolerability of Performing Portable MRI for Neurological Disorders in an Outpatient Neurology Clinic: A Prospective Cohort

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background Accessing brain magnetic resonance imaging (MRI) can be challenging, especially for underserved patients, which may lead to disparities in neurological diagnosis. Method This mixed‐methods study enrolled adults with one of four neurological disorders: mild cognitive impairment or dementia of the Alzheimer type, multiple sclerosis ...
Maya L. Mastick, Nomin Enkhtsetseg, Joseph Sadok, Matheus Mochetti, Annabel Sorby Adams, Jennifer Guo, Cristina Trapaga Hacker, Isabella Gomez Hjerthen, Seungwon Lee, Siddharth Satish, Andrew S. Ham, Justin Hill, Denis Balaban, Kevin Kyle, Rebecca L. Gillani, Marcelo Matiello, Aleksandar Videnovic, Eric C. Klawiter, W. Taylor Kimberly, Farrah J. Mateen   +19 more
wiley   +1 more source

Parallel ICA identifies sub-components of resting state networks that covary with behavioral indices

Frontiers in Human Neuroscience, 2012
Parallel Independent Component Analysis (para-ICA) is a multivariate method that can identify complex relationships between different data modalities by simultaneously performing Independent Component Analysis on each data set while finding mutual ...
Timothy eMeier, Joseph eWildenberg, Joseph eWildenberg, Jingyu eLiu, Jingyu eLiu, Jiayu eChen, Jiayu eChen, Vince eCalhoun, Vince eCalhoun, Bharat eBiswal, Mary eMeyerand, Mary eMeyerand, Mary eMeyerand, Rasmus eBirn, Rasmus eBirn, Rasmus eBirn, Vivek ePrabhakaran, Vivek ePrabhakaran, Vivek ePrabhakaran, Vivek ePrabhakaran   +19 more
doaj   +1 more source

Structure–Function Decoupling of the Sensorimotor and Default Mode Networks in Black Americans With MS

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background and Objectives Multiple sclerosis (MS) exhibits racially disparate rates of disease progression. Black people with MS (B‐PwMS) experience a more severe disease course than non‐Hispanic White people with MS (NHW‐PwMS). Here we investigated structural and functional connectivity as well as structure–function decoupling in the ...
Emilio Cipriano, Giacomo Boffa, Maria Petracca, Marta Ponzano, Nicole Graziano, Claire Wigley, Claire Riley, Jonathan Howard, Pietro Bontempi, Sylvia Klineova, Fred Lublin, Matilde Inglese   +11 more
wiley   +1 more source

Effects of Age on Resting‐State Cortical Networks

Human Brain Mapping
ABSTRACT Understanding how ageing affects brain function remains a central challenge in neuroscience. Electrophysiological brain imaging techniques provide a near‐direct measure of neuronal activity, which is useful for characterising neurophysiological health.
Chetan Gohil, Oliver Kohl, Jemma Pitt, Mats W.J. van Es, Andrew J Quinn, Diego Vidaurre, Martin R Turner, Anna C. Nobre, Mark W Woolrich   +8 more
openaire   +2 more sources

Task-related changes in resting state connectivity are affected by temporal interference (TI) stimulation

Brain Stimulation
Background: Resting-state metrics, such as brain network activity and functional connectivity (FC), are influenced by preceding cognitive tasks, such as memory formation.
Danielle Lauren Kurtin, Ketevan Alania, Edward Rhodes, Samuel Vincent, Ines R. Violante, Nir Grossman   +5 more
doaj   +1 more source

Prominent Changes in Cerebro-Cerebellar Functional Connectivity During Continuous Cognitive Processing

Frontiers in Cellular Neuroscience, 2018
While task-dependent responses of specific brain areas during cognitive tasks are well established, much less is known about the changes occurring in resting state networks (RSNs) in relation to continuous cognitive processing.
Gloria Castellazzi, Gloria Castellazzi, Gloria Castellazzi, Stefania D. Bruno, Ahmed T. Toosy, Letizia Casiraghi, Letizia Casiraghi, Fulvia Palesi, Giovanni Savini, Giovanni Savini, Egidio D’Angelo, Egidio D’Angelo, Claudia Angela Michela Gandini Wheeler-Kingshott, Claudia Angela Michela Gandini Wheeler-Kingshott, Claudia Angela Michela Gandini Wheeler-Kingshott   +14 more
doaj   +1 more source