Results 61 to 70 of about 361,308 (287)

Hemodynamic and electrophysiological evidence of resting-state network activity in the primate

open access: yes, 2008
An expanding body of literature describes the existence of concerted brain activations in the absence of any external stimuli. Resting-state networks have been identified and demonstrated to be modulated during the performance of specific cognitive ...
Wei Shen   +4 more
core   +1 more source

Dynamic Reconfiguration of Functional Topology in Human Brain Networks: From Resting to Task States

open access: yesNeural Plasticity, 2020
Task demands evoke an intrinsic functional network and flexibly engage multiple distributed networks. However, it is unclear how functional topologies dynamically reconfigure during task performance. Here, we selected the resting- and task-state (emotion
Wenhai Zhang   +3 more
doaj   +1 more source

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

open access: yesFEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa   +5 more
wiley   +1 more source

Stomach-brain synchrony reveals a novel, delayed-connectivity resting-state network in humans

open access: yeseLife, 2018
Resting-state networks offer a unique window into the brain’s functional architecture, but their characterization remains limited to instantaneous connectivity thus far.
Ignacio Rebollo   +3 more
doaj   +1 more source

THE RELATIONSHIP BETWEEN THE DEFAULT MODE RESTING STATE NEURAL NETWORK, RESPIRATORY SINUS ARRHYTHMIA, AND SELF-FOCUSED COGNITION: AN EMPIRICAL ANALYSIS [PDF]

open access: yes, 2013
Functional activity within the default mode resting state neural network (RSNN) and the resting respiratory sinus arrhythmia (RSA) may represent an integrated neural and peripheral cardiovascular index of the baseline, resting state in humans.
Egizio, Victoria
core  

Linking neurogenesis, oligodendrogenesis, and myelination defects to neurodevelopmental disruption in primary mitochondrial disorders

open access: yesFEBS Letters, EarlyView.
Mitochondrial remodeling shapes neural and glial lineage progression by matching metabolic supply with demand. Elevated OXPHOS supports differentiation and myelin formation, while myelin compaction lowers mitochondrial dependence, revealing mitochondria as key drivers of developmental energy adaptation.
Sahitya Ranjan Biswas   +3 more
wiley   +1 more source

Resting-state networks in the macaque at 7T

open access: yesNeuroImage, 2011
Assessment of brain connectivity has revealed that the structure and dynamics of large-scale network organization are altered in multiple disease states suggesting their use as diagnostic or prognostic indicators. Further investigation into the underlying mechanisms, organization, and alteration of large-scale brain networks requires a homologous ...
R. Matthew Hutchison   +5 more
openaire   +5 more sources

Resting state network estimation in individual subjects [PDF]

open access: yesNeuroImage, 2013
Resting state functional magnetic resonance imaging (fMRI) has been used to study brain networks associated with both normal and pathological cognitive functions. The objective of this work is to reliably compute resting state network (RSN) topography in single participants.
Carl D. Hacker   +6 more
openaire   +3 more sources

Modulation of Homer1 EVH1 domain internal dynamics by putative autism‐associated mutations

open access: yesFEBS Letters, EarlyView.
The putative autism‐associated M65I and S97L variants of the EVH1 domain of the postsynaptic scaffold protein Homer1 do not exhibit substantial changes in their overall structure or partner binding. Both of them, but especially the M65I variant, show altered internal dynamics relative to the wild‐type domain on the μs‐ms timescale, indicated by the ...
Fanni Farkas   +6 more
wiley   +1 more source

Multiscale network activity in resting state fMRI [PDF]

open access: yes2016 38th Annual International Conference of the IEEE Engineering in Medicine and Biology Society (EMBC), 2016
The brain is inherently multiscalar in both space and time. We argue that this multiscalar nature is reflected in the blood oxygenation level dependent (BOLD) fluctuations used to map functional connectivity. We present evidence that global fluctuations in activity, quasiperiodic spatiotemporal patterns, and aperiodic time-varying activity coexist ...
Shella D. Keilholz   +7 more
openaire   +2 more sources

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