Hemodynamic and electrophysiological evidence of resting-state network activity in the primate
An expanding body of literature describes the existence of concerted brain activations in the absence of any external stimuli. Resting-state networks have been identified and demonstrated to be modulated during the performance of specific cognitive ...
Wei Shen +4 more
core +1 more source
Dynamic Reconfiguration of Functional Topology in Human Brain Networks: From Resting to Task States
Task demands evoke an intrinsic functional network and flexibly engage multiple distributed networks. However, it is unclear how functional topologies dynamically reconfigure during task performance. Here, we selected the resting- and task-state (emotion
Wenhai Zhang +3 more
doaj +1 more source
Structural insights into an engineered feruloyl esterase with improved MHET degrading properties
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa +5 more
wiley +1 more source
Stomach-brain synchrony reveals a novel, delayed-connectivity resting-state network in humans
Resting-state networks offer a unique window into the brain’s functional architecture, but their characterization remains limited to instantaneous connectivity thus far.
Ignacio Rebollo +3 more
doaj +1 more source
THE RELATIONSHIP BETWEEN THE DEFAULT MODE RESTING STATE NEURAL NETWORK, RESPIRATORY SINUS ARRHYTHMIA, AND SELF-FOCUSED COGNITION: AN EMPIRICAL ANALYSIS [PDF]
Functional activity within the default mode resting state neural network (RSNN) and the resting respiratory sinus arrhythmia (RSA) may represent an integrated neural and peripheral cardiovascular index of the baseline, resting state in humans.
Egizio, Victoria
core
Mitochondrial remodeling shapes neural and glial lineage progression by matching metabolic supply with demand. Elevated OXPHOS supports differentiation and myelin formation, while myelin compaction lowers mitochondrial dependence, revealing mitochondria as key drivers of developmental energy adaptation.
Sahitya Ranjan Biswas +3 more
wiley +1 more source
Resting-state networks in the macaque at 7T
Assessment of brain connectivity has revealed that the structure and dynamics of large-scale network organization are altered in multiple disease states suggesting their use as diagnostic or prognostic indicators. Further investigation into the underlying mechanisms, organization, and alteration of large-scale brain networks requires a homologous ...
R. Matthew Hutchison +5 more
openaire +5 more sources
Resting state network estimation in individual subjects [PDF]
Resting state functional magnetic resonance imaging (fMRI) has been used to study brain networks associated with both normal and pathological cognitive functions. The objective of this work is to reliably compute resting state network (RSN) topography in single participants.
Carl D. Hacker +6 more
openaire +3 more sources
Modulation of Homer1 EVH1 domain internal dynamics by putative autism‐associated mutations
The putative autism‐associated M65I and S97L variants of the EVH1 domain of the postsynaptic scaffold protein Homer1 do not exhibit substantial changes in their overall structure or partner binding. Both of them, but especially the M65I variant, show altered internal dynamics relative to the wild‐type domain on the μs‐ms timescale, indicated by the ...
Fanni Farkas +6 more
wiley +1 more source
Multiscale network activity in resting state fMRI [PDF]
The brain is inherently multiscalar in both space and time. We argue that this multiscalar nature is reflected in the blood oxygenation level dependent (BOLD) fluctuations used to map functional connectivity. We present evidence that global fluctuations in activity, quasiperiodic spatiotemporal patterns, and aperiodic time-varying activity coexist ...
Shella D. Keilholz +7 more
openaire +2 more sources

