Catheterization and Cardiovascular Interventions, 2023 AbstractBackgroundQuantitative flow ratio (QFR) is a novel, software‐based method to evaluate the physiology of coronary lesions. The aim of this study was to compare QFR with the established invasive measurements of coronary blood flow using instantaneous wave‐free ratio (iFR) or resting full‐cycle ratio (RFR) in daily cathlab routine.Methods102 ...
Jannis Stader +9 more
openaire +2 more sources
Methods and protocols for incremental exercise testing in tetraplegia, using arm-crank ergometry assisted by Functional Electrical Stimulation [PDF]
, 2009 Cervical spinal cord injury (SCI) leads to tetraplegia, with paralysis and loss of sensation in the upper and lower limbs. The associated sedentary lifestyle results in an increased risk of cardiovascular disease.
A.N. McLean +24 more
core +1 more source
Heterogeneity in HIV and cellular transcription profiles in cell line models of latent and productive infection: implications for HIV latency. [PDF]
, 2019 BackgroundHIV-infected cell lines are widely used to study latent HIV infection, which is considered the main barrier to HIV cure. We hypothesized that these cell lines differ from each other and from cells from HIV-infected individuals in the mechanisms
Aran, Dvir +10 more
core +1 more source
Debate: Angiography-derived FFR. The angiographic perspective
REC: Interventional Cardiology (English Ed.), 2020 QUESTION: Compared to the pressure guidewire what possible advantages does coronary angiography-derived fractional flow reserve (FFRangio) have and what is the current clinical evidence?
Ignacio J. Amat Santos
doaj +1 more source
Porous-based rheological model for tissue fluidisation [PDF]
, 2016 It has been experimentally observed that cells exhibit a fluidisation process when subjected to a transient stretch, with an eventual recovery of the mechanical properties upon removal of the applied deformation.
Asadipour, Nina +2 more
core +2 more sources
Export fluxes in a naturally iron-fertilized area of the Southern Ocean – Part 2: Importance of diatom resting spores and faecal pellets for export [PDF]
Biogeosciences, 2015 The biological composition of the material exported to a moored sediment trap located under the winter mixed layer of the naturally fertilized Kerguelen Plateau in the Southern Ocean was studied over an annual cycle.
M. Rembauville +8 more
doaj +1 more source
European Heart Journal, 2020 Abstract Introduction Fractional flow reserve (FFR) is a gold standard method to evaluate functional lesion severity in daily clinical practice. Recently, the resting full-cycle ratio (RFR) which was newly developed resting indices was launched.
H Ohashi +10 more
openaire +1 more source
Physiologically motivated multiplex Kuramoto model describes phase diagram of cortical activity [PDF]
, 2014 We derive a two-layer multiplex Kuramoto model from weakly coupled Wilson-Cowan oscillators on a cortical network with inhibitory synaptic time delays.
Sadilek, Maximilian, Thurner, Stefan
core +2 more sources
A debate: RFF derivada de la angiografía. Perspectiva desde la angiografía
REC: Interventional Cardiology, 2020 PREGUNTA: ¿Qué posibles ventajas tiene respecto a la guía de presión y cuáles son las evidencias clínicas actuales de la reserva fraccional de flujo calculada por angiografía (angio-RFF)?
Ignacio J. Amat Santos
doaj +1 more source
Exploiting metabolic adaptations to overcome dabrafenib treatment resistance in melanoma cells
Molecular Oncology, EarlyView.We show that dabrafenib‐resistant melanoma cells undergo mitochondrial remodeling, leading to elevated respiration and ROS production balanced by stronger antioxidant defenses. This altered redox state promotes survival despite mitochondrial damage but renders resistant cells highly vulnerable to ROS‐inducing compounds such as PEITC, highlighting redox
Silvia Eller +17 more
wiley +1 more source