Results 61 to 70 of about 921,081 (288)

Topological Fractionation of Resting-State Networks

PLoS ONE, 2011
Exploring topological properties of human brain network has become an exciting topic in neuroscience research. Large-scale structural and functional brain networks both exhibit a small-world topology, which is evidence for global and local parallel information processing. Meanwhile, resting state networks (RSNs) underlying specific biological functions
Ding, JR, Liao, W, Zhang, Z, Mantini, D, Xu, Q, Wu, G, Lu, G, Chen, H   +7 more
openaire   +5 more sources

Rested-state contractions and rest potentiation in spontaneously hypertensive rats. [PDF]

Hypertension, 1993
To gain further insight into the excitation-contraction coupling mechanisms in hypertrophy, we studied rested-state contractions, rest decay curves, and rest potentiation under different experimental conditions using papillary muscles of spontaneously hypertensive rats (SHR) and age-matched normotensive Wistar and Wistar-Kyoto (WKY) rats.
Pérez, Néstor Gustavo, Vila Petroff, Martín Gerardo, Mattiazzi, Alicia Ramona   +2 more
openaire   +3 more sources

Function‐driven design of a surrogate interleukin‐2 receptor ligand

FEBS Letters, EarlyView.
Interleukin (IL)‐2 signaling can be achieved and precisely fine‐tuned through the affinity, distance, and orientation of the heterodimeric receptors with their ligands. We designed a biased IL‐2 surrogate ligand that selectively promotes effector T and natural killer cell activation and differentiation. Interleukin (IL) receptors play a pivotal role in
Ziwei Tang, Zelin Cheng, Teng Li, Fulian Wang, Liangminghui Zhang, Xiuxiu He, Lili Liu, Wei Wang, Aibin Liang, Guang Yang   +9 more
wiley   +1 more source

Sequence determinants of RNA G‐quadruplex unfolding by Arg‐rich regions

FEBS Letters, EarlyView.
We show that Arg‐rich peptides selectively unfold RNA G‐quadruplexes, but not RNA stem‐loops or DNA/RNA duplexes. This length‐dependent activity is inhibited by acidic residues and is conserved among SR and SR‐related proteins (SRSF1, SRSF3, SRSF9, U1‐70K, and U2AF1).
Naiduwadura Ivon Upekala De Silva, Puspa Kunwar, Md Ibnul Rifat Rahman, Joanna Koryo Kwao, Nathan Lehman, Zihan Zhang, Trenton Paul, Claire Cheng, Nicholas Truex, Hui‐Ting Lee, Jun Zhang   +10 more
wiley   +1 more source

Resting-state “Physiological Networks” [PDF]

, 2019
AbstractSlow changes in systemic brain physiology can elicit large fluctuations in fMRI time series, which may manifest as structured spatial patterns of temporal correlations between distant brain regions. These correlations can appear similar to large-scale networks typically attributed to coupled neuronal activity.
Chen, Jingyuan E., Lewis, Laura D., Chang, Catie, Fultz, Nina E., Ohringer, Ned A., Rosen, Bruce R., Polimeni, Jonathan R.   +6 more
openaire   +1 more source

Functional connectomics from resting-state fMRI [PDF]

Trends in Cognitive Sciences, 2013
Spontaneous fluctuations in activity in different parts of the brain can be used to study functional brain networks. We review the use of resting-state functional MRI (rfMRI) for the purpose of mapping the macroscopic functional connectome. After describing MRI acquisition and image-processing methods commonly used to generate data in a form amenable ...
Smith, S, Vidaurre, D, Beckmann, C, Beckmann, C, Beckmann, C, Glasser, M, Jenkinson, M, Miller, K, Nichols, T, Nichols, T, Robinson, E, Salimi-Khorshidi, G, Woolrich, M, Woolrich, M, Barch, D, Uǧurbil, K, Van Essen, D   +16 more
openaire   +4 more sources

Cell wall target fragment discovery using a low‐cost, minimal fragment library

FEBS Letters, EarlyView.
LoCoFrag100 is a fragment library made up of 100 different compounds. Similarity between the fragments is minimized and 10 different fragments are mixed into a single cocktail, which is soaked to protein crystals. These crystals are analysed by X‐ray crystallography, revealing the binding modes of the bound fragment ligands.
Kaizhou Yan, Mathew Stanley, Olawale Raimi, Andrew T. Ferenbach, Helge C Dorfmueller, Daan M. F. van Aalten   +5 more
wiley   +1 more source

Alterations in resting-state activity relate to performance in a verbal recognition task. [PDF]

PLoS ONE, 2013
In the brain, resting-state activity refers to non-random patterns of intrinsic activity occurring when participants are not actively engaged in a task.
Rocío A López Zunini, Jean-Philippe Thivierge, Shanna Kousaie, Christine Sheppard, Vanessa Taler   +4 more
doaj   +1 more source

Latent functional connectivity underlying multiple brain states

Network Neuroscience, 2022
Functional connectivity (FC) studies have predominantly focused on resting state, where ongoing dynamics are thought to reflect the brain’s intrinsic network architecture; thought to be broadly relevant because it persists across brain states (i.e ...
Ethan M. McCormick, Katelyn L. Arnemann, Takuya Ito, Stephen José Hanson, Michael W. Cole   +4 more
doaj   +1 more source

Maturation trajectories of cortical resting-state networks depend on the mediating frequency band [PDF]

, 2018
The functional significance of resting state networks and their abnormal manifestations in psychiatric disorders are firmly established, as is the importance of the cortical rhythms in mediating these networks. Resting state networks are known to undergo
Bekhti, Yousra, Bharadwaj, Hari, Ganesan, Santosh, Garel, Keri-Lee A., Gollub, Randy L., Hamalainen, Matti S., Hashmi, Javeria A., Kenet, Tal, Khan, Sheraz, Kitzbichler, Manfred G., Kong, Jian, Mamashli, Fahimeh, Michmizos, Konstantinos, Rana, Kunjan D., Stufflebeam, Steven M., Vaina, Lucia M., Whitfield-Gabrieli, Susan   +16 more
core   +1 more source