Results 211 to 220 of about 88,462 (245)

Tunable Enhancement of T Cell Expansion Through Modulation of Stiffness and Adhesion Receptor Engagement in an Engineered Hydrogel Platform

Advanced Materials, EarlyView.
We develop a hydrogel scaffold with controlled substrate stiffness and ligand functionalization for cell culture. Stiff substrates presenting CD3/CD28/CD2 ligands induce 2000‐fold expansion of T cells; this is 68% greater than the clinical standard (Dynabeads) and the first hydrogel capable of large‐scale expansion. Although expanding at a lower yield,
Niroshan Anandasivam, Rabia Ali, Lordean Gustinvil, Matthew J. Rosenwasser, Iain E. Dunlop, Derfogail Delcassian   +5 more
wiley   +1 more source

PiP‐Plex: A Particle‐in‐Particle System for Multiplexed Quantification of Proteins Secreted by Single Cells

Advanced Materials, EarlyView.
Detecting proteins secreted by a single cell while retaining its viability remains challenging. A particles‐in‐particle (PiPs) system made by co‐encapsulating barcoded microparticles (BMPs) with a single cell inside an alginate hydrogel particle is introduced.
Félix Lussier, Byeong‐Ui Moon, Mojra Janta‐Polczynski, Yonatan Morocz, Fabian Svahn, Molly Shen, Ljuboje Lukic, Lidija Malic, Teodor Veres, Andy Ng, David Juncker   +10 more
wiley   +1 more source

Resting-State Networks of Awake Adolescent and Adult Squirrel Monkeys Using Ultra-High Field (9.4 T) Functional Magnetic Resonance Imaging. [PDF]

eNeuro
Yassin W, de Moura FB, Withey SL, Cao L, Kangas BD, Bergman J, Kohut SJ.   +6 more
europepmc   +1 more source

A Soft Microrobot for Single‐Cell Transport, Spheroid Assembly, and Dual‐Mode Drug Screening

Advanced Materials, EarlyView.
A soft, untethered hydrogel microrobot enables precise single‐cell delivery, self‐assembly into 3D spheroids, and real‐time thermal actuation. Driven by light‐induced convection and embedded with gold nanorods and temperature sensors, the microrobot guides cells, modulates local microenvironments, and supports drug testing.
Philipp Harder, Nergishan İyisan, Yukun Wang, Berna Özkale   +3 more
wiley   +1 more source

Aberrant Functional Connectivity of the Salience Network in Adult Patients with Tic Disorders: A Resting-State fMRI Study [PDF]

Linda Orth, Johanna Meeh, Delia Leiding, Ute Habel, Irene Neuner, Pegah Sarkheil   +5 more
openalex   +1 more source

Engineered Protein‐Based Ionic Conductors for Sustainable Energy Storage Applications

Advanced Materials, EarlyView.
Rational incorporation of charged residues into an engineered, self‐assembling protein scaffold yields solid‐state protein films with outstanding ionic conductivity. Salt‐doping further enhances conductivity, an effect amplified in the engineered variants. These properties enable the material integration into an efficient supercapacitor.
Juan David Cortés‐Ossa, Paolo Blesio, Marcial Fernandez‐Castro, Lisa Almonte, Maxence Fernandez, Mantas Liutkus, Perumal Pandurangan, Carlos Sabater, Aitor Villaverde, Manuel Melle‐Franco, Nurit Ashkenasy, Felipe Jiménez‐Ángeles, M. Carmen Morant‐Miñana, M. Reyes Calvo, Aitziber L. Cortajarena   +14 more
wiley   +1 more source

Multifunctional Fluidic Units for Emergent, Responsive Robotic Behaviors

Advanced Materials, EarlyView.
A multifunctional reconfigurable fluidic unit can be used as sensor, valve and actuator is presented. A unique configuration combines the features of the three components as a Responsive self‐oscillating actuator. The remarkable versatility of the fluidic unit is demonstrated by building different robots with the same fluidic units only by varying ...
Mostafa Mousa, Alberto Comoretto, Johannes T.B. Overvelde, Antonio E. Forte   +3 more
wiley   +1 more source

Association between the functional brain network and antidepressant responsiveness in patients with major depressive disorders: a resting-state EEG study [PDF]

Kang‐Min Choi, Hyeon-Ho Hwang, Chaeyeon Yang, Bori Jung, Chang‐Hwan Im, Seung‐Hwan Lee   +5 more
openalex   +1 more source

Beyond Presumptions: Toward Mechanistic Clarity in Metal‐Free Carbon Catalysts for Electrochemical H2O2 Production via Data Science

Advanced Materials, EarlyView.
Metal‐free carbon catalysts enable the sustainable synthesis of hydrogen peroxide via two‐electron oxygen reduction; however, active site complexity continues to hinder reliable interpretation. This review critiques correlation‐based approaches and highlights the importance of orthogonal experimental designs, standardized catalyst passports ...
Dayu Zhu, Hsi‐wen Wu, Xiao Wang, Jie Zhang   +3 more
wiley   +1 more source