Results 111 to 120 of about 235,919 (281)
Molecular Oncology, EarlyView.Generation of two normal and tumour (cancerous) paired human cell lines using an established tissue culture technique and their characterisation is described. Cell lines were characterised at cellular, protein, chromosome and gene expression levels and for HPV status.
Simon Broad +12 more
wiley +1 more source
Victim Restitution and other Financial Remedies, September 27, 2012 [PDF]
, 2012 Restitution is court ordered payment of crime related expenses to a victim by an offender. The Judge can order restitution as part of the offender’s sentence.
core
Molecular Oncology, EarlyView.The noncoding region of the genome plays a key role in regulating gene expression, and mutations within these regions are capable of altering it. Researchers have identified multiple functional noncoding mutations associated with increased cancer risk in the genome of breast cancer patients.
Arnau Cuy Saqués +3 more
wiley +1 more source
Bulgaria. A relatively short organic history [PDF]
, 2003 Organic agriculture in Bulgaria has a relatively short history. The concept of organic agriculture was only introduced after the fall of the communist regime in 1990, when the process of land restitution started.
Apostolov, Stoylko, Heeb, Marlene
core
Strength through diversity: how cancers thrive when clones cooperate
Molecular Oncology, EarlyView.Intratumor heterogeneity can offer direct benefits to the tumor through cooperation between different clones. In this review, Kuiken et al. discuss existing evidence for clonal cooperativity to identify overarching principles, and highlight how novel technological developments could address remaining open questions.
Marije C. Kuiken +3 more
wiley +1 more source
Potential therapeutic targeting of BKCa channels in glioblastoma treatment
Molecular Oncology, EarlyView.This review summarizes current insights into the role of BKCa and mitoBKCa channels in glioblastoma biology, their potential classification as oncochannels, and the emerging pharmacological strategies targeting these channels, emphasizing the translational challenges in developing BKCa‐directed therapies for glioblastoma treatment.
Kamila Maliszewska‐Olejniczak +4 more
wiley +1 more source
Exploiting metabolic adaptations to overcome dabrafenib treatment resistance in melanoma cells
Molecular Oncology, EarlyView.We show that dabrafenib‐resistant melanoma cells undergo mitochondrial remodeling, leading to elevated respiration and ROS production balanced by stronger antioxidant defenses. This altered redox state promotes survival despite mitochondrial damage but renders resistant cells highly vulnerable to ROS‐inducing compounds such as PEITC, highlighting redox
Silvia Eller +17 more
wiley +1 more source
Implementasi Hak Restitusi Terhadap Korban Tindak Pidana Perdagangan Orang
Lareh Law ReviewRestitution can be interpreted as the right of victims of criminal acts provided by the perpetrators or third parties as a form of loss recovery and legal protection for victims, which can be in the form of compensation for material and/or immaterial ...
Annisa Novianti, Teno Frimer
doaj
Affectio Societatis, 2014 In Seminar VI, Desire and its Interpretation (1958- 59), Jacques Lacan examines and interprets the dream and fantasies of an Ella Sharp's patient.
Ana Victoria Saldarriaga
doaj
ATF4‐mediated stress response as a therapeutic vulnerability in chordoma
Molecular Oncology, EarlyView.We screened 5 chordoma cell lines against 100+ inhibitors of epigenetic and metabolic pathways and kinases and identified halofuginone, a tRNA synthetase inhibitor. Mechanistically halofuginone induces an integrated stress response, with eIF2alpha phosphorylation, activation of ATF4 and its target genes CHOP, ASNS, INHBE leading to cell death ...
Lucia Cottone +11 more
wiley +1 more source