Results 31 to 40 of about 53,353 (296)
Frontiers in Physiology, 2018 We investigated the steepened dynamic action potential duration (APD) restitution of rats with pulmonary artery hypertension (PAH) and right ventricular (RV) failure and tested whether the observed APD restitution properties were responsible for negative
Matthew E. L. Hardy +6 more
doaj +1 more source
Reciprocal control of viral infection and phosphoinositide dynamics
FEBS Letters, EarlyView.Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley +1 more source
Experimental study and numerical simulation of the vertical bounce of a polymer ball over a wide temperature range [PDF]
, 2014 The dependence to temperature of the rebound of a solid polymer ball on a rigid slab is investigated. An acrylate polymer ball is brought to a wide range of temperatures, covering its glass to rubbery transition, and let fall on a granite slab while the ...
GILORMINI, Pierre +2 more
core +1 more source
Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?
FEBS Letters, EarlyView.This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes +3 more
wiley +1 more source
FEBS Letters, EarlyView.We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley +1 more source
The dynamic viscoelastic characterisation of the impact behaviour of the GAA sliotar [PDF]
, 2010 In recent years variability in behaviour of the sliotar, a small leather-bound ball used in the Irish sport of hurling, became evident in championship matches. The current standard has not provided adequate repeatability of ball performance. A new method
Kieran Moran +5 more
core +1 more source
, 2023 Background: The experience of living with children with CP is dominated by the voice of the mother while others are rarely reported. Incorporation of the voices of other family members is important for a holistic understanding.
Lymn, J. S. +5 more
core +1 more source
The Role of Local Communities in the Discourse of Controversial Heritage of Norway and Estonia
Ochrona Dziedzictwa Kulturowego, 2022 This chapter analyses paradigm shifts in the discourse of heritage sites connected with tragic personal stories, memories and relics, emphasising local communities’ role in reframing controversial heritage in Norway and Estonia.
Ave Paulus, Arnstein Bard Brekke
doaj +1 more source
Structural insights into an engineered feruloyl esterase with improved MHET degrading properties
FEBS Letters, EarlyView.A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa +5 more
wiley +1 more source
Epidermoid Cyst Arising in the Submandibular Region
Case Reports in Medicine, 2013 Dermoid and epidermoid cysts in the oral cavity frequently develop in the midline or sublingual region of the floor of the mouth. Here, we report a rare case of an epidermoid cyst in the submandibular region.
Masanori Kudoh +3 more
doaj +1 more source