Results 71 to 80 of about 226,037 (263)

Pre–emption right of shareholders to purchase shares for sale in private limited liability companies: the problematic legal remedies

Business: Theory and Practice, 2016
This article analyses the problems that can arise when implementing the rights of shareholders in private limited liability companies to purchase the shares of another shareholder being for sale in priority to others and the possible legal remedies for ...
Virginijus Bitė, Žygimantas Narkevičius   +1 more
doaj   +1 more source

A Mass-Spring-Damper Model of a Bouncing Ball (Conference proceeding) [PDF]

, 2005
The mechanical properties of a vertically dropped ball, represented by an equivalent mass-spring-damper model, are related to the coefficient of restitution and the time of contact of the ball during one bounce with the impacting surface. In addition, it
Huang, Shuguang, Nagurka, Mark L.
core   +1 more source

Cytoplasmic p21 promotes stemness of colon cancer cells via activation of the NFκB pathway

Molecular Oncology, EarlyView.
Cytoplasmic p21 promotes colorectal cancer stem cell (CSC) features by destabilizing the NFκB–IκB complex, activating NFκB signaling, and upregulating BCL‐xL and COX2. In contrast to nuclear p21, cytoplasmic p21 enhances spheroid formation and stemness transcription factor CD133.
Arnatchai Maiuthed, Kerstin Huebner, Katharina Erlenbach‐Wuensch, Chuanpit Hampel, Daniela Thalheim, Adriana Vial‐Roehe, Bodee Nutho, Susanne Merkel, Arndt Hartmann, Pithi Chanvorachote, Regine Schneider‐Stock   +10 more
wiley   +1 more source

CAUSES AND CONSEQUENCES OF ECONOMIC CRIMES LINKAGE IN THE CONTEMPORARY REALITIES OF INTEGRATION PROCESSES

Baltic Journal of Economic Studies, 2020
The economically and socially advanced countries of the world have encountered a number of issues that are not new and examples of the systematic recurrence of which are known in Europe, Asia, America, Africa.
Rostyslav Lemekha, Bogdan Schur
doaj   +1 more source

Coefficient of normal restitution of viscous particles and cooling rate of granular gases

, 1997
We investigate the cooling rate of a gas of inelastically interacting particles. When we assume velocity dependent coefficients of restitution the material cools down slower than with constant restitution.
A. Hatzes, A. Mehta, A. P. Hatzes, C. K. K. Lun, E. Grossman, F. G. Bridges, G. Kuwabara, H. Hertz, I. Goldhirsch, J. Blum, J. M. Luck, K. D. Supulver, K. L. Johnson, K. Shida, N. A. Burnham, N. Schörghofer, N. V. Brilliantov, P. Constantin, P. K. Haff, S. E. Esipov, S. McNamara, S. McNamara, T. Zhou, Thomas Schwager, Thorsten Pöschel, Y. Du, Y. H. Pao   +26 more
core   +1 more source

Cis‐regulatory and long noncoding RNA alterations in breast cancer – current insights, biomarker utility, and the critical need for functional validation

Molecular Oncology, EarlyView.
The noncoding region of the genome plays a key role in regulating gene expression, and mutations within these regions are capable of altering it. Researchers have identified multiple functional noncoding mutations associated with increased cancer risk in the genome of breast cancer patients.
Arnau Cuy Saqués, Aracele Martinez‐Mendez, John Crown, Alex Eustace   +3 more
wiley   +1 more source

Specificities of the property restitution procedure under the law of the Republic of Serbia

Pravo
In all the republics of the former Yugoslavia, including in the Republic of Serbia, property relations were highly dynamic, with the answer to the question of who held ownership rights frequently changing.
Jasna Selaković, Predrag Mirković
doaj   +1 more source

Potential therapeutic targeting of BKCa channels in glioblastoma treatment

Molecular Oncology, EarlyView.
This review summarizes current insights into the role of BKCa and mitoBKCa channels in glioblastoma biology, their potential classification as oncochannels, and the emerging pharmacological strategies targeting these channels, emphasizing the translational challenges in developing BKCa‐directed therapies for glioblastoma treatment.
Kamila Maliszewska‐Olejniczak, Karolina Pytlak, Sandra Jaworowska, Bogusz Kulawiak, Piotr Bednarczyk   +4 more
wiley   +1 more source

Exploiting metabolic adaptations to overcome dabrafenib treatment resistance in melanoma cells

Molecular Oncology, EarlyView.
We show that dabrafenib‐resistant melanoma cells undergo mitochondrial remodeling, leading to elevated respiration and ROS production balanced by stronger antioxidant defenses. This altered redox state promotes survival despite mitochondrial damage but renders resistant cells highly vulnerable to ROS‐inducing compounds such as PEITC, highlighting redox
Silvia Eller, Susanne Ebner, Carmen Haselrieder, Julia K. Günther, Astrid Drasche, Sophie Strich, Chiara Volani, Andrea Medici, Aleksandar Nikolajevic, Alex Deltedesco, Johannes E. Sigmund, Michael J. Blumer, Martin Hermann, Johanna Vanacker, Gerald Brandacher, Eduard Stefan, Omar Torres‐Quesada, Jakob Troppmair   +17 more
wiley   +1 more source

ATF4‐mediated stress response as a therapeutic vulnerability in chordoma

Molecular Oncology, EarlyView.
We screened 5 chordoma cell lines against 100+ inhibitors of epigenetic and metabolic pathways and kinases and identified halofuginone, a tRNA synthetase inhibitor. Mechanistically halofuginone induces an integrated stress response, with eIF2alpha phosphorylation, activation of ATF4 and its target genes CHOP, ASNS, INHBE leading to cell death ...
Lucia Cottone, James Dunford, Eleanor Calcutt, Vicki Gamble, Filiz Senbabaoglu Aksu, Lorena Ligammari, Georgina Wherry, Giorgia Gaeta, John C. Christianson, Adrienne M. Flanagan, Udo Oppermann, Adam P. Cribbs   +11 more
wiley   +1 more source