Results 71 to 80 of about 231,538 (286)

Valosin‐containing protein counteracts ATP‐driven dissolution of FUS condensates through its ATPase activity in vitro

open access: yesFEBS Letters, EarlyView.
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura   +2 more
wiley   +1 more source

Discrete particle simulation of bubble and slug formation in a two-dimensional gas-fluidised bed: a hard-sphere approach. [PDF]

open access: yes, 1996
A discrete particle model of a gas-fluidised bed has been developed and in this the two-dimensional motion of the individual, spherical particles was directly calculated from the forces acting on them, accounting for the interaction between the particles
Briels, W.J.   +3 more
core   +3 more sources

Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation

open access: yesFEBS Letters, EarlyView.
Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz   +11 more
wiley   +1 more source

The ubiquitin ligase RNF115 is required for the clearance of damaged lysosomes

open access: yesFEBS Letters, EarlyView.
Upon lysosomal rupture, an E3 ubiquitin ligase RNF115 translocates from the cytosol to the damaged lysosomal membrane. Moreover, RNF115 depletion impairs the clearance of damaged lysosomes, identifying it as a key regulator of lysosomal quality control.
Sae Nakanaga   +3 more
wiley   +1 more source

Specificities of the property restitution procedure under the law of the Republic of Serbia

open access: yesPravo
In all the republics of the former Yugoslavia, including in the Republic of Serbia, property relations were highly dynamic, with the answer to the question of who held ownership rights frequently changing.
Jasna Selaković, Predrag Mirković
doaj   +1 more source

AAA+ protein unfoldases—the Moirai of the proteome

open access: yesFEBS Letters, EarlyView.
AAA+ unfoldases are essential molecular motors that power protein degradation and disaggregation. This review integrates recent cryo‐electron microscopy (cryo‐EM) structures and single‐molecule biophysical data to reconcile competing models of substrate translocation.
Stavros Azinas, Marta Carroni
wiley   +1 more source

Cinq masques de l’Iyoba Idia du royaume de Bénin : vies sociales et trajectoires d’un objet multiple

open access: yesPerspective, 2019
The five ivory masks of the Queen Mother Idia (16th century), which are now in London, New York, Seattle, Stuttgart, and in an English private collection, are without doubt the most iconic art objects from the African continent if we are to judge by ...
Felicity Bodenstein
doaj   +1 more source

Tracer diffusion in granular shear flows

open access: yes, 2002
Tracer diffusion in a granular gas in simple shear flow is analyzed. The analysis is made from a perturbation solution of the Boltzmann kinetic equation through first order in the gradient of the mole fraction of tracer particles.
A. Santos   +35 more
core   +2 more sources

Potential therapeutic targeting of BKCa channels in glioblastoma treatment

open access: yesMolecular Oncology, EarlyView.
This review summarizes current insights into the role of BKCa and mitoBKCa channels in glioblastoma biology, their potential classification as oncochannels, and the emerging pharmacological strategies targeting these channels, emphasizing the translational challenges in developing BKCa‐directed therapies for glioblastoma treatment.
Kamila Maliszewska‐Olejniczak   +4 more
wiley   +1 more source

Collections et bibliothèques d’art spoliées par les nazis, deux pertes irréparables

open access: yesPerspective, 2016
Research in recent years has shed some light on one of the continually undervalued aspects of Nazi violence: the plundering across Europe, and particularly in France, of thousands (or millions) of objects of cultural property.
Martine Poulain
doaj   +1 more source

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